Academia.edu no longer supports Internet Explorer.
To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to upgrade your browser.
2010 •
Molecular Psychiatry
The molecular genetic architecture of human personality: beyond self-report questionnaires2006 •
2005 •
2006 •
1998 •
Mediterranean Journal of Hematology and Infectious Diseases
Association of VDBP rs4701 variant, but not VDR/RXR-α over-expression with bone mineral density in pediatric β-Thalassemia patients2020 •
Introduction: The reduced rate of bone formation despite the availability of vitamin D has been reported in β-thalassemia. This suggests genetic factors together with environmental one can be implicated in this condition. Since vitamin D binding protein (VDBP) maintains bioavailability of vitamin D which binds to vitamin D receptor (VDR)-retinoid X receptor alpha (RXRA) heterodimer to exert its molecular actions, we speculated that vitamin D metabolic-axis expression signature and variants could be potential molecular candidates for bone turnover/disease in thalassemia. To this end, this study aims to analyze VDR/RXRA expression signature, and two VDBP variants in a pilot sample of Egyptian β-thalassemia children in correlation with bone mineral density (BMD). Patients and methods: Forty-four β-thalassemia children and 40 unrelated controls were enrolled. The serum bone chemistry profile was measured. Peripheral blood mononuclear cells (PBMN) VDR/RXRA expression levels were quantif...
Community genetics
Attitudes towards genetic diagnosis in Pakistan: a survey of medical and legal communities and parents of thalassemic children2007 •
2011 •
Magnetic Resonance in Medicine
Effects of Myocardial Water Exchange onT1 Enhancement during Bolus Administration of MR Contrast Agents1995 •
International Journal of Construction Management
Risk factors influencing the building projects in Pakistan: from perspective of contractors, clients and consultants2019 •
2013 •
2014 •
arXiv (Cornell University)
Is the dynamical quantum Cheshire cat detectable?2022 •