Opting for local region in SHOX2 promoter as a DNA methylation biomarker for lung cancer diagnosis

In this study, formalin-fixed, paraffin-embedded (FFPE) tissue samples were collected from 30 lung cancer patients and 30 patients suffering from non-cancerous pulmonary diseases. The methylation level of SHOX2 was evaluated in two CpG-riched regions of the promoter by using qMSP.