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Signaling pathways

Tìm thấy 20+ kết quả cho từ khóa "Signaling pathways"

Transcriptomic profiling revealed key signaling pathways for cold tolerance and acclimation of two carp species

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Candidate genes up-regulated in groups III and IV (f and g) during cold acclimation of Barbless carp were mainly enriched in signaling pathways such as insulin signaling pathway, PPAR signaling pathways, adipocyto- kine signaling pathway and ribosome biogenesis in eukaryotes (Fig.

Pathways involved in pony body size development

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This result implies that the SNP in GHR pro- moters might alter the binding motifs and lead to the different gene expression levels in the two breeds.. 6 Signaling pathways regulating short stature in the Debao pony. a The GHR signaling pathway regulates short stature in the Debao pony. b The WNT5A and TLR2 signaling pathways regulate short stature in the Debao pony.

Genome-wide expression and network analyses of mutants in key brassinosteroid signaling genes

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Our analysis identified ABA signaling as a mainly com- pensatory pathway, and hormone signaling pathways re- lated to ethylene, auxin, and ROS, as pathways involved in partially restoring the bri1–5 expression phenotype to WS2 levels.

Identification of the molecular regulation of differences in lipid deposition in dedifferentiated preadipocytes from different chicken tissues

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The expression levels of DEGs related to lipid metabolism determined by qRT-PCR in the DIMFPs and DAFPs. 0.05) in DIMFPs and DAFPs. 6 Proposed regulatory network for the difference in lipid deposition in DIMFPs and DAFPs based on DEGs and enriched signaling pathways. Forty-seven enriched pathways were screened, including the well-known path- ways affecting lipid metabolism (MAPK, TGF beta, Wnt, calcium, and PPAR signaling pathways as well as the pathways related to cell communication).

Identification and characterization of circRNAs in the skin during wool follicle development in Aohan fine wool sheep

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A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. NF-kappaB in the epidermis. Involvement of a novel Tnf receptor homologue in hair follicle induction. Controlling hair follicle signaling pathways through polyubiquitination. Generation of the primary hair follicle pattern. Edar signaling in the control of hair follicle development. EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction.

Transcriptome dynamics in early in vivo developing and in vitro produced porcine embryos

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During the morula to the hatched blastocyst transition, both in vivo developed and in vitro produced embryos displayed an enrichment of the pathways 14–3-3-medi- ated signaling, xenobiotic metabolism general signaling pathways, and NRF2-mediated oxidative stress response..

Phytohormone and integrated mRNA and miRNA transcriptome analyses and differentiation of male between hermaphroditic floral buds of andromonoecious Diospyros kaki Thunb

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In the auxin signaling pathways, the AUX/IAA genes and one of the ARFs (CL2880.Contig4_All) were upregu- lated, whereas the other ARF (CL2880.Contig6_All) was downregulated in the male floral buds at stage 2.. In the gibberellin signaling pathways, the DELLA genes and one TF (CL4250.Contig11_All) were highly upregu- lated in the male floral buds at stage 2..

Gene co-expression network analysis reveals key pathways and hub genes in Chinese cabbage (Brassica rapa L.) during vernalization

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In summary, we tried to find the biological function of two different bolting Chinese cabbage accessions during the vernalization process: the early-bolting ‘ XBJ ’ could bolt and flower faster at 25 DAT, which was promoted by the shoot system morphogenesis and polysaccharide and sugar metabolism, while late-bolting ‘ JWW ’ enriched chitin, ABA, and ethylene-activated signaling pathways at 35 DAT, indicating that these regulatory. pathways may promote bolting resistance in Chinese cabbage.

Hydrogen cyanamide induces grape bud endodormancy release through carbohydrate metabolism and plant hormone signaling

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Differentially expressed genes and proteins involved in metabolic, ribosomal, and hormonal signaling pathways are significantly enriched between HC treatment and a control treatment [13]. b Developmental stages of the grape buds sampled in this study. On 16 d, the bud breaking rate was 97.85 and 57.62% in the HC treatment group and CK group, respectively.

The seasonal development dynamics of the yak hair cycle transcriptome

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For example, genes involved in the synthesis of intermediate filament and. keratin filament, the Wnt signaling pathway, signaling pathways regulating the pluripotency of stem cells, the Hippo signaling pathway and the MTOR and Hedgehog signaling pathways are greatly enriched among the genes that show peak expression in the anagen and catagen (Clusters C1, C2 and C3).

RNA-Seq reveals differential expression profiles and functional annotation of genes involved in retinal degeneration in Pde6c mutant Danio rerio

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Twenty-four genes are involved in insulin signaling pathways, and they are down-regulated in mutant zebra- fish. Our results showed that all the insulin signaling pathway genes are downregulated in the mutant zebra- fish and may be involved in the retinal degeneration mechanism.

Proteome of larval metamorphosis induced by epinephrine in the Fujian oyster Crassostrea angulata

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The unique signaling pathways in the PL-einSEN group included adrenergic signaling in cardiomyocytes, dopaminergic synapse, insulin signaling pathway, and. Although the expression of these proteins was down-regulated in the eSEN group, only three proteins (calmodulin, ryanodine receptor, calcium/calmodulin-dependent protein kinase).

Integrated mRNA and miRNA transcriptome analysis reveals a regulatory network for tuber expansion in Chinese yam (Dioscorea opposita)

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PE2.1 and PE53 are the members of pectinesterase (PE) super- family, which may be involved in the regulation of starch and sucrose metabolism and signaling pathways. Tuber morphogenesis is a complex biological process involving many specific genes and proteins, espe- cially at yam tuber expansion stage.

Ontogeny of hepatic metabolism in mule ducks highlights different gene expression profiles between carbohydrate and lipid metabolic pathways

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Data on early chicken embryogenesis suggest that hepatic induction of the anterior endoderm via an interaction with the “cardiac” mesoderm [14] in- volves many of the pathways depicted in Fig. Nevertheless, al- though much of the cell proliferation and hepatic differ- entiation arise at the earliest stages of liver development [17], our results suggest that these signaling pathways.

Chicken cecal DNA methylome alteration in the response to Salmonella enterica serovar Enteritidis inoculation

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The enriched Wnt signaling path- way, TGF-β signaling pathway and mTOR signaling pathway may indicate that SE inoculation would affect the chicken immune and metabolism through altering gene DNA methylation in related signaling pathways.. HOX genes, a conserved gene family, play crucial roles in embryonic development and is involved in the reproduction and development of cells [64].

Hair follicle regional specificity in different parts of bay Mongolian horse by histology and transcriptional profiling

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The hair follicle size, density, and cycle among different types of hair follicles are suggested to be related to ALP activity, angiogenesis, stem cells, WNT, and IGF signaling pathways. These factors and pathways may regulate the regional specificity by control- ling the hair follicle morphogenesis and pigmentogenesis..

MicroRNA profiling in the Weddell seal suggests novel regulatory mechanisms contributing to diving adaptation

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For example, VEGF signaling was targeted by both novel and annotated miRNAs in the seal heart, highlighting the importance of vascular development in cardiac tissue. 0.05, see Methods) for the targets of miRNAs that were highest in the brain and 31 pathways were enriched for targets of muscle-elevated miRNAs, which are primarily signaling pathways.

Transcriptome analysis of the transdifferentiation of canine BMSCs into insulin producing cells

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All of the DEGs, including upregulated and downregu- lated transcripts, were annotated to signaling pathways related to the GO terms. stage 1” DEGs were mapped to 230 KEGG pathways, while the “stage 1 vs. stage 2,” “stage 2 vs. 3 Top 20 KEGG signaling pathways of known transcripts, the size of bubbles represented for mapped gene numbers of the item, and the color was measured by the Qvalue. a KEGG analysis of “ BMSCs vs stage 1. b KEGG analysis of “ stage 1 vs stage 2. c KEGG analysis of “ stage

A global analysis of CNVs in Chinese indigenous fine-wool sheep populations using whole-genome resequencing

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In addition, Wnt- related signaling pathways were also enriched in some of the CNVR-harboring genes in the AMS_no group. Through the analysis of KEGG signaling pathways, it was found that some of the CNVR-harboring genes were enriched for signaling pathways correlated with wool growth and development. It has been reported that, as one of the important pathways in the follicle development process, the Jak-STAT signaling pathway can stimulate MAPK to influence follicle development [44].

Sirt2-associated transcriptome modifications in cisplatin-induced neuronal injury

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Cisplatin-induced differential signaling pathways which are associated with Sirt2 status. Pathway analysis showed a significant difference of cisplatin-induced pathways dependent on Sirt2 status (Fig. Fewer pathways were induced by cisplatin in Sirt2-expressing cells than in Sirt2-deficient cells. Fur- thermore, the following pathways were induced only in Sirt2-deficient cells: p53, ECM–receptor interaction, and cytokine–cytokine receptor interaction pathways.