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Pharmaceutical Substances Syntheses, Patents, Applications - Part 40

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10.6.1977).. 28.7.1977).. Use: antibiotic RN MF: C,,H,3N,04S, MW: 525.64. CN: (6R-trans)-7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[l-[2-(dimethyla~no)ethyl]-lH-tetrazol-5- yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. RN MF: C,,H,3N,04S3 . 24.12.1974. 21.3.1978. 20.12.1974. 27.8.1977. 27.3.1979. 29.8.1977. Use: antibiotic RN MF: Cl,H1,N,O,S, MW: 427.46 EINECS LD. CN: (GR-cis)-3-[[(aminocarbonyl)oxyJmethyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)aminoJ-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. RN MF: C,,H,,N,NaO,S, MW: 449.44 EINECS LD. 3(S)-hydroxymethyl-7-methoxy- 7-[Z-(2-thienyl)acetamido]- 3-cephem-4-carboxylic acid potassium salt. a,c US Merck &. 27.10.1981. DOS Merck &. 26.1.1972. 27.1.1971).. US...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 41

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28.4.1983. 18.6.1984. 20.6.1983).. 17.7.1981).. 21.8.1984. 2.10.1979).. 1.10.1980. 16.4.1983).. 10.4.1984. 10.9.1982).. Use: antibiotic RN MF: C,,H,,N,O,S, MW: 440.49. 10.4.1968. RN MF: C13H13N,0,S2 MW: 383.41. RN MF: C13H13NS05S2. RN MF: Cl,HI,N,NaO,S, MW: 405.39 LD. 24.1.1984. RN MF: CI8HI8N8O7S3 MW: 554.59 EINECS: 277-405-6. RN MF: C18H,6N,Na,07S3 MW: 598.55 EINECS LD,: 2200 mgkg (M, i.v. 14.2.1984. 17.2.1981).. RN MF: C,6H16N408S M W : 424.39...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 42

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Use: diagnostic (for pancreatic function), stimulant of gastric secretory RN MF: C5RH73N1302LS2 MW: 1352.42. RN MF: C2,H,,BrN0 MW: 448.57. RN MF: CxHSoCINO MW: 404.12. Use: vasodilator (peripheral) RN MF: C,,,H3,N0,S MW: 349.54 EINECS: 238-028-2. RN MF: C2,,H3,N02S . Use: non-sedative antihistaminic RN MF: C21H25C1N203 MW: 388.90. RN MF: C21H25CIN203 .2HCI MW: 461.82 LD,: 365 mg/kg (R, p.0.);. 10.4.1996).. 4.10.1996).. 11.7.1996).....

Pharmaceutical Substances Syntheses, Patents, Applications - Part 43

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10 mglkg (M, i.v. numerous combination preparations. 1100 mglkg (M, p.o.1;. 1500 mglkg (M, p.0.);. 300 mglkg (M, p.0.);. RN MF: C,,H,,ClN,O. 1400 mglkg (M, p.0.);. 1260 mglkg (M, p.0.);

Pharmaceutical Substances Syntheses, Patents, Applications - Part 44

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500 mg/kg (dog, p.0.). Use: fungistatic, antifungal RN MF: C,,H,,CIN, MW: 256.74 EINECS: 222-998-9. RN MF: C,,H,,ClN,. D07AB Use: topical glucocorticoid RN MF: C,,H,CIO, MW: 434.92 EINECS: 237-919-3. RN MF: C13HI,C1N,0. RN MF: C,,H2,C1N3 . Trade Name(s):. 105 mg/kg (M, i.p.). 438 mg/kg (M, p.0.). 3 1 1 mglkg (M, p.0.);. RN MF: C,8H26CIN,. RN MF: C,8H2,CIN3. RN MF: C,,H,CIN....

Pharmaceutical Substances Syntheses, Patents, Applications - Part 45

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20 mglkg (M, i.v. 121 mglkg (M, p.0.);. 1 18 mglkg (R, p.0.). 26.1 mglkg (M, i.v. 306 mglkg (R, p.0.);. as maleate)-comb.. as maleate). as maleate) Atrohist (Medeva. as maleate) Codimal (Schwarz. as maleate) Dallergy 1 (Laser. as maleate) Extendryl (Fleming. as maleate) Kronofec (Ferndale. as maleate) Notamine (Carnrick. as maleate) Ornace (SmithKline Beecham. as maleate) Pediacof (Sanofi. as...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 46

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Trade Name(s):. RN MF: unspecified MW: unspecified EINECS LD5,: >7.5 g/kg (M, p.0.);. >4 glkg (R, p.0.) CN: cholestyramine. powder 4 g Trade Name(s):. Co.) GB: Questran (Bristol-Myers USA: Locholest (Warner Chilcott. 300 mglml Trade Name(s):. CN: 2-hydroxy-N,N,N-trimethylethanaminium hydroxide. Choline hydroxide. RN MF: C5H14N0 . CN: 2-hydroxy-N,N,N-trimethylethanaminium salicylate (1: I). 500 mg1100 ml Trade Name(s):. Use: anti-inflammatory, liver therapeutic RN...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 47

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Use: diuretic, antihypertensive RN MF: C14H,2ClN02 MW: 261.71. RN MF: C,4H,2ClN02~ HCl MW: 298.17. Use: glucocorticoid RN MF: C32HuClN07 MW: 590.16 EINECS: 289-141-9. Use: antispasmodic, anticholinergic RN MF: C22H3,BrN0 MW: 408.42 EINECS: 249-687-0. Use: antifungal RN MF: C,,H,,NO, MW: 207.27 EINECS CN: 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone. RN MF: C,,H,,N02 . Use: immunosuppressive RN MF: C,,Hll,N,,O,, MW: 1202.64. et al.: Helv. Use: choleretic, hepatic...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 48

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RN MF: C,,H,,N,S MW: 252.35. 150 mg/kg (M, i.v. 2550 mglkg (M, p.0.);. 206 mg/kg (dog, i.v. US Smith Kline &. 20.4.1972).. 28.12.1976. DOS Smith Kline &. 13.4.1976. 29.2.1972 and 20.9.1972). 21.9.1977: GB-prior. GB Smith Kline &. 20.8.1976. 20.8.1975 and . FR Smith Kline &French. 16.8.1976. valid from 9.3.1972).. DAS Smith Kline &. 19.4.1977. 4.12.1975. 22.3.1977. 5.10.1976. BE 853 954...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 49

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RN MF: C13H,4C1203 MW: 289.16 EINECS CN dichlorocyc1opropyl)phenoxy]-2-mehy1propanoic acid. S03AA07 Use: antibacterial RN MF: C17H,,FN303 MW: 331.35. RN MF: C17H,,FN303 . RN MF: Cl,H18FN303 . RN MF: C17H18FN303. RN MF: CI7Hl8FN3O3. 28.10.1986. Use: gastrokinetic, promotility RN MF: C2,H2,C1FN,O4 MW: 465.95 EINECS: 279-689-7. RN MF: C2,H2,C1FN,O4 . RN MF: CS3H,2N20,r 2C6H503S MW: 1243.50. RN MF: C,,H,2N20,2 MW: 929.16. Use: antineoplastic RN...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 50

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RN MF: C6H,,N303. RN MF: C,,H,,CIN,O, MW: 285.69 CN: 2-chloro-2'-deoxyadenosine. Use: P-lactamase inhibitor RN MF: C,H,NO, MW: 199. RN MF: C,H,NNa05 MW: 221.14 EINECS LD. Use: anti-emetic, specific antagonist of peripheral and central dopamine receptors, reversible MAO-inhibitor RN MF: CzoHz4CIN,02 MW. 4850 mglkg (R, s.c.) CN: 4-amino-5-chloro-2-methoxy-N-[l-(phenylmethyl)-4-piperidinyl]benzamide. RN MF: C2,H2,C1N30. RN MF: C,,Hz4CIN,0z . R06AA04 Use: antiallergic, antihistaminic RN MF:...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 51

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29.1.1970. Use: antibiotic RN MF: C,,H&1N,05S MW: 424.99 EINECS LDso: 2618 m g k g (R, s.c.). RN MF: C,,H&IN205S . 245 mglkg (M, i.v. 24.12.1968. 28.10.1969. 28.4.1970. 30.4.1968).. RN MF: C2,H3,0, MW: 468.59. 255 mglkg (M, i.p. 1800 mglkg (M, p.0. 410 mglkg (M, s.c.);. A 0 0 0 mglkg (R, p.o.1. 2200 mglkg (R, s.c.) CN: 2,2'-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methylbutanoic acid]....

Pharmaceutical Substances Syntheses, Patents, Applications - Part 52

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IJse: glucocorticoid RN MF: C2,H2,C1FO4 MW: 41 0.9 1 EINECS: 225-406-7. RN MF: C2,H,,C1F05 MW: 495.03 EINECS caproate. RN MF: C2,H,,ClF05 MW: 509.06 EINECS: 225-513-9. as pivalate-comb.) pivalate and capronate) Kaban (Asche. as and capronate-comb.) capronate)-comb.. ATC: GOlAXOl Use: fungicide RN MF: CI,HI,CI3N,O2S MW: 347.69 EINECS LDS. (Clodronic acid disodium salt) Use: calcium metabolism regulator RN MF: CH2CI,Na,0,P, MW: 288.86...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 53

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6.12.1958. 12.1.1959).. 5.12.1959. 6.12.1958).. ATC: JOIAAII Use: antibiotic RN MF: C2,H,,C1N,0, MW. Use: anticonvulsant RN MF: C15HloC1N,03 MW: 3 15.72 EINECS . 31.12.1963. 2.12.1960).. 17.4.1964).. Use: antihypertensive RN MF: CYHyCl2N, MW: 230.10 EINECS . RN MF: CYHyCl2N. DE 1303 141 (Boehringer Ing.. 9.10.1961).. US Boehringer Ing.. BE 653 933 (Boehringer Ing.. 2.10.1964. 4.10.1963. GB Boehringer Ing.. 2.10.1962. 28.9.1964. 12.7.1968).. Catapresan...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 54

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23.10.1978. vial 30 mg Trade Name(s):. Use: bronchodilator RN MF: CIIHl,CINO MW: 213.71 EINECS: 223-291-8. RN MF: C,lH16C1N0 . RN MF: Cl,HI4ClN MW: 183.68 CN: 2-chloro-a,a-dimethylbenzeneethanamine hydrochloride. RN MF: Cl,H14ClN . 10.12.1968. 50 mg Trade Namefs):. RN MF: Cl,H,7C10, MW: 322.88 EINECS: 214-133-9. 26.10.1M6. Use: anxiolytlc, benzodiazepine analog RN MF: C,,H,,ClN,OS MW: 318.83 EINECS: 251-627-3. 5 mg, 10 mg, 20...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 55

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LDm: 535 mg/kg (M, p.0.) hydriodide. RN MF: C40H80NOHP. Use: antibiotic (macrocyclic peptide) RN MF: unspecified MW: unspecified EINECS: 213-907-3. RN MF: H204S . RN MF: unspecified MW: unspecified EINECS LD,&. Use: glucocorticoid RN MF: C3,H3,N20s MW: 530.67 EINECS: 214-175-8. Use: cardiac preparation, cardiac stimulant RN MF: C4H,,N,04P MW: 197.13 EINECS: 230-011-8. RN MF: C4H,,N,Na,04P MW: 241.10. RN MF: C,,H,5CIN20...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 56

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with crotetarnide) Trade Name(s):. 10 % Trade Name(s):. 25.10.1974. 10.10.1978. 200 mg, 400 mg Trade Name(s):. RN MF: Cl,H,2N2. RN MF: C,,H,,N,O. RN MF: C,,,H,,N . 4820 mglkg (R, p.0.) CN: a-ethyl-1-hydroxycyclohexaneacetic acid monosodium salt. RN MF: C,,H,,Na03 MW: 208.23 EINECS calcium salt. RN MF: C,,H,,O,~ xCa MW: unspecified betaine salt (1:l). RN MF: CI,,H1703 . 100 mg, 200 mg,...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 58

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Shealy, J.E et al.: J. RN MF: C2,H,,N02 MW: 337.46 EINECS LD. et al.: J. RN MF: C,4HI,,N40s MW: 314.26 EINECS LD. RN MF: C,,H,N,NaO. SOlEXO2 Use: antipsychotic, antiglaucoma RN MF: C,,H,,N, MW: 325.46. 260 mglkg (M, i.p.). RN MF: C,,H,,NS. 250 mglkg (M, p.0.);. 1 .@kg (R, p.o.1. et al.: Org. RN MF: C,H,,NO,, MW: 527.53 EINECS LD. 5...