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Pharmaceutical Substances Syntheses, Patents, Applications - Part 180

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Use: ulcer therapeut~c RN MF: C,,H,,ClN,O, MW: 370.79. et al.: Chem. RN MF: CI,H2,NO3 MW: 313.40. RN MF: C,,HZ3NO3 . ATC: NOlAH06 Use: analgesic RN MF: C2,H2,N20S MW: 376.45. RN MF: C20H2xN205 . RN MF: C,,H2,BrN,0, MW: 371.28. RN MF: C,,H,,BrN,O. RN MF: C2,H3,N2O4 MW: 452.60 I. RN MF: C44H7,CaN40, MW: 823.14 racemate. RN MF: C2,H,,N,04 MW: 452.60. et al.:...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 181

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combination preparations;. numerous combination preparations. 432mglkg (M, 1.v.);4100mg/kg(M,p.o.). generics and circa 300 combination preparations A 313. Vitamine A Faure (ThBa) numerous combination preparations. J: numerous combination preparations. and circa 300 combination preparations. GB: only combination preparations:. combination preparations:

Pharmaceutical Substances Syntheses, Patents, Applications - Part 182

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10.8.1976).. Use: antibiotic (tuberculosis agent) RN MF: C43H58N4012 MW: 822.95 EINECS: 236-312-0. 24.10.1978. 12.8.1958).. RN MF: C47H,N40,2 MW: 877.05 EINECS CN: 3-[[(4-Cyclopentyl-l-piperazinyl)iminv]methyl]rifamycin. RN MF: C,HSIN,O,, MW: 785.89 LD,: >2 glkg (R, p.0.);. 18.12.1979. RN MF: C2,H2,Cl2N6O3 . RN MF: C,,,H,6N20 MW: 180.25 EINECS LD. RN MF: C,oH,6N20. RN MF: C,,H,,N20. 17.12.1973. 26.10.1976. 26.12.1973. RN MF: C,H,F,N,OS MW: 234.20 LD. use...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 183

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16.9.1995. 11.2.1994).. b WO Abbott Labs.. 26.9.1994. WO Abbott Labs.. 17.7.1995. 29.7.1994).. 30.4.1994. I WO Abbott Labs.. 25.2.1995).. 31.8.1994).. RN MF: C,,Hz2N2O2 MW: 250.34. RN MF: CIsHl,N. RN MF: C,,Hl,Ns MW: 269.35. 19.5.1995. 24.5.1994).. RN MF: C1,HI4O4S MW: 314.36

Pharmaceutical Substances Syntheses, Patents, Applications - Part 184

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29.7.1996).. 2.10.1994. 12.9.1995. 16.9.1994).. 15.5.1995. 15.5.1996. 18.5.1995).. 9.10.1995. 18.12.1995. 12.5 mg Trade Name(s):. denvative, treatment of leukopenia associated with cancer radiotherapy RN MF: C43H7RN6013 MW: 887.13. 9.10.1986).. Use: antihyperlipoproteinemic, fibrate serum antihyperlipidemic RN MF: C19H,oClN05 MW: 377.82. Use: dopamine-D,-agonist, antiparkinsonian RN MF: C,,H,N,O MW: 260.38. RN MF: C,6H,N,0 . WO Smith Kline &. 7.12.1982).. US Smith Kline &. AU Smith...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 185

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W O SmithKline Beecham. c W O SmithKline Beecham. d W O SmithKline Beecham. W SmithKline Beecham. RN MF: C,7H14N203 MW: 294.31 EINECS CN: l-ethyl-l,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid sodium salt. RN MF: Cl7HI3N2NaO3 MW: 316.29. RN MF: C1,H2,N204 MW: 348.44 LD. RN MF: C. ATC: JOlMAlO Use: antibacterial RN MF: C17H18FN303S . RN MF: C,7H,,FN303S MW: 363.41. RN MF: C,,,H,CaN,O,S, MW: 404.44...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 186

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metered-dose aerosol 0.12 mg. powder 0.12 mg, 0.24 mg. 300 mglkg (M, p.0.);. 980 mglkg (R, p.0.) CN: 2-hydroxybenzamide. S p i r s i u r e ) Use: keratolytic, antipyretic, antirheumatic RN: 69-72-7 MF: C,H,O, MW: 138.12 EINECS: 200-712-3. 184 mglkg (M, i.v. 480 mglkg (M, p.0.);. 891 mglkg (R, p.0.) CN: 2-hydroxybenzoic acid monosodium salt. 560 mglkg...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 187

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et al.: Arzneim.-Forsch. RhGne- Poulenc). Use: diagnostic, hormon (pancreatic) RN MF: unspecified MW: unspecified EINECS: 215-733-3. 23.10.1 973. et al.. et al.: J . et al.: Chern. et al.: Chem. ATC: N048D01 Use: antiparkinsonian RN MF: Ci3HI7N MW: 187.29. RN MF: C1,H,,N . 30.5.1988).. (Peking) (JCCOAV) 18, I61 (1951) Jung et al.: J. RN MF: C,,H,,O, MW: 354.45 LD. RN...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 188

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et al.: J. Weizmann et al.: J. Use: anesthetic (inhalation) RN MF: C,H,F,O MW: 200.05. 10.8 g k g (R, p.0. 28800 p p d 3 H (R, inhal.) CN hexafluoro-2-(fluorornethoxy)propane. 28.10.1969. 17.10.1989. Use: antidepressant, anorexic RN MF: CI ,H2,C1N . RN MF: C1,H2,C1N MW anhydrous hydrochloride. RN MF: Cl ,H2,C1N . RN MF: CI7H2,ClN MW hydrochloride. RN MF: C,,H2,C1N...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 189

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RN MF: C22H74N4010 MW: 514.53 LD. >I glkg (M, p.0.);. RN MF: C,H,Au04S . RN MF: C,H,Au04S MW: 346.14 EINECS: 246-034-1. RN MF: C,,H,,NaO,S MW: 444.57 EINECS CN: sulfobutanedioic acid 1,4-bis(2-ethylhexyl) ester sodium salt. RN MF: C20H,7K0,S MW: 460.67 EINECS: 231-308-5. RN MF: C,,H,,NNa,O,S, MW: 481.41 EINECS LD. Use: ulcer therapeutic RN MF: C,,H,,,O, MW: 450.53. 131 mglkg(M,i.v.);>10g/kg(M, p.0.);. numerous...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 190

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22.6.1962).. 15.12.1964. 5200 mglkg (dog, p.0.) CN: spiramycin. 5.12.1961. et al.: Antibiot. RN MF: C2,H,,,N20SS2 . 6.12.1982. 12.3.1987. 12.3.1987).. 19.12.1983. 31.10.1986. 28.10.1987. et al.: Synthesis (SYNTBF) 1986, 81.. et al.: Tetrahedron (TETRAB . 12.12.1961. 22.12.1960. 10.12.1959. et al.: J. 1.10.1963).. 12.6.1973. 22.10.1973. 4.10.1973. 5.10.1972).. 1.12.1978. 2.12.1977).. et al.: Chem. RN MF: C2,H2,N904 . 22.6.1965. et al.: Gazz. 22.7.1964. Use: anti-AIDS...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 191

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20.2.1992. 11.6.1992. 23.12.1992. 17.8.1992. 29.12.1992. 12.5.1988. 25.6.1992. 5.12.1992. Use: mucolytic, hepatic protectant RN MF: C,,H,,NO,S, MW: 273.33 EINECS: 276-587-4. >2500 mgtkg (R, p.0.) CN: N-[1-oxo-2-[(2-thienylcarbonyl)thio]propyl]glycine. RN MF: C,,H,,NNaO,S, MW: 295.32. Use: fibrinolytic (plasminogen activator) RN MF: unspecified MW: unspecified EINECS: 232-647-1. RN MF: C,,H,,N,O,Z. JWA Use: tuberculostatic RN MF: C,,H,N,,O,, MW: 700.71. RN MF: C2,H,NloO1,. ATC: LOIAD04 Use: antineoplastic RN...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 192

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Use: ulcer therapeutic RN MF: C,2H54A116075SN MW: 2086.73 EINECS LD. 11.3.1969. 3.11.1966. Use: narcotic, analgesic RN MF: C2,H1,N20,S MW: 386.56. RN MF: C,2H,,N20,S , C,H,O, MW: 578.68 EINECS LD. 11.3.1976).. lactamase inhibitor RN MF: C8H,lNOSS MW: 233.24 EINECS: 269-878-2. RN MF: C,H,,NNaO,S MW: 255.23 EINECS: 273-984-4. Use: antibiotic RN MF: C,,HIRN2O,S2 MW: 414.46 EINECS: 252-209-3. RN MF: C,,H,,N,Na,O,S, MW: 458.42...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 193

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j 4-acetomidobenzene- sulfonyl chloride. CN: 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)henzenesulfonamide. 250 mg, 500 mg Trade Name(s):. CN: 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide. 4-acetomidobenzene- sulfonyl chloride. Trade Name(s):. CN: 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide. sulfonyl chloride 1 J.4-thiadiazole. CN: 4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide. 500 mg Trade Name(s):. CN: 4-amino-N-(arninoiminornethyl)benzenesulfonamide. Use: chemotherapeutic (depot sulfonamide). 400 mg Trade Name(s):. Use: chemotherapeutic (depot sulfonamidc). CN: 4-amino-N-(3-methoxypyrazinyl)benzenesulfonamide. 2 g Trade Name(s):. Use: chemotherapeutic (sulfonamide), antibacterial. CN: 4-amino-N-(4-methyl-2-pyrimld~nyl)benzenesulfonamlde sodium salt. CN:...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 194

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ATC: JOIED05 Use: chemotherapeutic. 1700 mglkg (M, p.0.);. CN: 4-amino-N-(6-methoxy-3-pyridazinyl)benzenesulfonamide. Use: chemotherapeutic (depot sulfonamide). Use: chemotherapeutic (in combination with trimethoprim). ATC: J01EB06 Use: chemotherapeutic KN: 63-74-1 MF: C6H8N202S MW: 172.21 EINECS: 200-563-4. Use: chemotherapeutic RN: 599-88-2 MF: C,,Hl2N,O2S MW: 264.31 EINECS: 209-976-4. CN: 4-amino-N-(5-methyl-2-pyrimidinyl)benzenesulfonamide. ATC: JOIED08 Use: chemotherapeutic RN: 526-08-9 MF: Cl5HI4N4O2S MW: 3 14.37 EINECS: 208-384-3. 3016 mglkg (M,...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 195

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Sulfoxone sodium S 1941 Trade Name(s):. 330 mg Trade Name(sJ:. RN MF: C2,H1,FO,S MW: 356.42 EINECS LD. 150 mg, 200 mg Trade Name(s):. RN MF: C,,JII9NO,S MW: 297.38 EINECS LD. Trade Name(s):. Use: vasodilator RN MF: C,,,H,,NOS MW: 337.57 EINECS CN: (R*,S*)-4-[(1-methylethyl)thio]-a-[1-(octylamino)ethyl]benzenemethanol. 14.7.1977).. 11.7.1977).. Trade Name(s): E. RN MF: C,,H2,N304S MW: 341.43 EINECS LD. RN MF: C,,H,,N40,S, MW: 594.67. vial...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 196

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Use: surfactant (for treatment of respiratory distress syndrome) RN MF: unspecified MW: unspecified. 3000 mg/kg (M, p.0.) CN: beractant. RN MF: C,H,,NO,. RN MF: C,,H,O, M W : 416.65. RN MF: CI,HI,N2. RN MF: C,,H,,N2

Pharmaceutical Substances Syntheses, Patents, Applications - Part 197

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antibacterial RN MF: C2,H2,N,06S MW: 481.53 EINECS: 256-332-3. RN MF: C,H,,N,O,S . RN MF: C20H33N307 MW: 363.50 LD. RN MF: C,oH1,N30. RN MF: C,,,H,,N3S MW: 209.32. RN MF: C,,H,,N,S .2HCI MW: 282.24 LD. (palliative treatment of breast cancer) RN MF: C,,H2,N0 MW: 371.52 EINECS . RN MF: C,,H,,NO. RN MF: CZoH2RN20SS HC1 MW: 444.98. RN MF: C2,H2,N2O5S MW hydrochloride. RN...

Pharmaceutical Substances Syntheses, Patents, Applications - Part 198

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Use: anxiolytic, antidepressant RN MF: C,,H2,N502 MW: 383.50. RN MF: C2,H2,N5O2. 18.1.1988. 28.5.1996. et al.: Chem. Use: antiallergic, antiasthmatic RN MF: C,,H,,N,O, MW: 289.30. 28.8.1985. 18.10.1988. RN MF: Cz1H2,NO2S MW: 351.47. RN MF: CRH7Cl4N3O4S2 MW: 415.11 EINECS: 224-253-3. et al.: J. ATC: LOIBC03 Use: antineoplastic RN MF: C,H9FN203 MW: 200.17 EINECS: 241-846-2. RN MF: C,H,FN,NaO, MW: 222.15. 14.10.1975. 10.1.1968).. 28.4.1975).....

Pharmaceutical Substances Syntheses, Patents, Applications - Part 199

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Use: antihypertensive (ACE inhibitor) RN MF: C2,H2,N20,S2 MW: 476.62. RN MF: Cz3Hz8N20,S. 16.10.1991. RN MF: C,,HI8N20,S2 MW: 414.46 EINECS: 266-184-1. RN MF: Cl,H,,N2Na207S2 MW: 458.42 EINECS: 262-835-9. Usc: antineoplastic (leucemia) RN MF: C,,H,,O,,S M W: 656.66 EINECS . 10.12.1966. RN MF: C,HsN,03S2 MW: 255.28 EINECS CN: N-(5-nitro-2-thiazolyl)-2-thiophenecarboxamide. RN MF: C,,H,,N30,S2 MW: 337.38 LD. Use: antihypertensive, a-blocker RN MF: C,yH,,Ns04 MW:...