« Home « Kết quả tìm kiếm

Neurochemical Mechanisms in Disease P51


Tóm tắt Xem thử

- Thus the specific response of a cell to a ligand will be determined as the sum of many variables, and net effect of different ligands depends upon all of these factors.
- Not all of the endogenous ligands have been discovered, and even fewer data are available about their interactions, therefore researchers need to continue identifying key cellular and molecular factors affected in sensory pathways during different pain syndromes to characterize potential targets for new drugs and drug combinations..
- Acknowledgments This work was supported by a grant of the National Research and Development Office, Hungary (OMFB-0066/2005/DNT) and a Hungarian Research Grant (OTKA, K60278).
- Abe K, Taguchi K, Kato M, Utsunomiya I, Chikuma T, Hojyo H, Miyatake T (2003) Characterization of muscarinic receptor subtypes in the rostral ventrolateral medulla and effects on morphine-induced antinociception in rats.
- Eur J Pharmacol .
- Adams ML, Brase DA, Welch SP, Dewey WL (1986) The role of endogenous peptides in the action of opioid analgesics.
- Afrah AW, Stiller CO, Olgart L, Brodin E, Gustafsson H (2001) Involvement of spinal N-methyl- D-aspartate receptors in capsaicin-induced in vivo release of substance P in the rat dorsal horn..
- Alger B, Le Beau F (2001) Physiology of the GABA and glycine systems.
- Alkondon M, Pereira EFR, Cortes WS, Maelicke A, Albuquerque EX (1997) Choline is a selective agonist of alpha 7 nicotinic acetylcholine receptors in the rat brain neurons.
- Brain Res .
- Almasi R, Szoke E, Bolcskei K, Varga A, Riedl Z, Sandor Z, Szolcsanyi J, Petho G (2008) Actions of 3-methyl-N-oleoyldopamine, 4-methyl-N-oleoyldopamine and N-oleoylethanolamide on the rat TRPV1 receptor in vitro and in vivo.
- Altier N, Stewart J (1993) Intra-VTA infusions of the substance P analogue, DiMe-C7, and intra- accumbens infusions of amphetamine induce analgesia in the formalin test for tonic pain.
- Altier N, Stewart J (1998) Dopamine receptor antagonists in the nucleus accumbens attenuate anal- gesia induced by ventral tegmental area substance P or morphine and by nucleus accumbens amphetamine.
- Altier N, Stewart J (1999) The role of dopamine in the nucleus accumbens in analgesia.
- Andrade R, Aghajanian GK (1982) Single cell activity in the noradrenergic A-5 region: responses to drugs and peripheral manipulations of blood pressure.
- Ansah OB, Pertovaara A (2007) Peripheral suppression of arthritic pain by intraarticular fadolmi- dine, an alpha 2-adrenoceptor agonist, in the rat.
- Azarov AV, Szabo G, Czako L, Telegdy G (1995) Effects of calcitonin gene-related peptide on acute and chronic effects of morphine.
- Ballet S, Mauborgne A, Benoliel JJ, Bourgoin S, Hamon M, Cesselin F, Collin E (1998) Polyarthritis-associated changes in the opioid control of spinal CGRP release in the rat.
- Brain Res 868:79–87.
- Bardin L, Schmidt J, Alloui A, Eschalier A (2000a) Effect of intrathecal administration of serotonin in chronic pain models in rats.
- Eur J Pharmacol 409:37–43.
- Bardin L, Lavarenne J, Eschalier A (2000b) Serotonin receptor subtypes involved in the spinal antinociceptive effect of 5-HT in rats.
- Barke KE, Hough LB (1993) Simultaneous measurement of opiate-induced histamine release in the periaqueductal gray and opiate antinociception: an in vivo microdialysis study.
- Bartho L, Lazar Z, Lenard L Jr, Benko R, Toth G, Penke B, Szolcsanyi J, Maggi CA (2000) Evidence for the involvement of ATP, but not of VIP/PACAP or nitric oxide, in the excitatory effect of capsaicin in the small intestine.
- Behbehani MM, Pert A (1984) A mechanism for the analgesic effect of neurotensin as revealed by behavioral and electrophysiological techniques.
- Brain Res 324:35–42.
- Bellasio S, Nicolussi E, Bertorelli R, Reggiani A (2003) Melanocortin receptor agonists and antagonists modulate nociceptive sensitivity in the mouse formalin test.
- Ben Shabat S, Fride E, Sheskin T, Tamiri T, Rhee MH, Vogel Z, Bisogno T, De Petrocellis L, Di Marzo V, Mechoulam R (1998) An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity.
- Eur J Pharmacol 353:23–31 Bereiter DA, Cioffi JL, Bereiter DF (2005) Oestrogen receptor-immunoreactive neurons in the.
- Bester H, De Felipe C, Hunt SP (2001) The NK1 receptor is essential for the full expression of noxious inhibitory controls in the mouse.
- Beyer C, Caba M, Banas C, Komisaruk BR (1991) Vasoactive intestinal polypeptide (VIP) potenti- ates the behavioral-effect of substance-P intrathecal administration.
- Bhatia M, Sidhapuriwala J, Moochhala SM, Moore PK (2005) Hydrogen sulphide is a mediator of carrageenan-induced hindpaw oedema in the rat.
- Bie B, Fields HL, Williams JT, Pan ZZ (2003) Roles of alpha1- and alpha2-adrenoceptors in the nucleus raphe magnus in opioid analgesia and opioid abstinence-induced hyperalgesia..
- J Neuroendocrinol 20:1–9 Bisogno T, Melck D, Bobrov MY, Gretskaya NM, Bezuglov VV, De Petrocellis L, Di Marzo V (2000) N-acyl-dopamines: novel synthetic CB1 cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimemetic activity in vitro and in vivo.
- Bitar MS, Al-Bustan M, Nehme CL, Pilcher CWT (1996) Antinociceptive action of intrathecally admistered IGF-I and the expression of its receptor in rat spinal cord.
- Brain Res Bjorklund A, Skagerberg G (1979) Evidence for a major spinal cord projection from the dien-.
- cephalic A11 dopamine cell group in the rat using transmitter-specific fluorescent retrograde tracing.
- Bodnar RJ, Kelly DD, Mansour A, Glusman M (1979) Differential effects of hypophysectomy upon analgesia induced by two glucoprivic stressors and morphine.
- G, Szolcsanyi J (2005) Investigation of the role of TRPV1 receptors in acute and chronic nociceptive processes using gene-deficient mice.
- Boom A, Mollereau C, Meunier JC, Vassart G, Parmentier M, Vanderhaeghen J-J, Schiffmann SN (1999) Distribution of the nociceptin and nocistatin precursor transcript in the mouse central nervous system.
- effects of GDNF in neuropathic pain states.
- Bradley KJ, Headley PM (1997) Effect of agmatine on spinal nociceptive reflex: lack of interaction with alpha2-adrenoceptor or mu-opioid receptor mechanisms.
- Bridges RS, Ronsheim PM (1987) Immunoreactive beta-endorphin concentrations in brain and plasma during pregancy in rats – possible modulation by progesterone and estradiol..
- Brumovsky P, Stanic D, Shuster S, Herzog H, Villar M, Hokfelt T (2005) Neuropeptide Y2 receptor protein is present in peptidergic and nonpeptidergic primary sensory neurons of the mouse.
- Bruzzone F, Lectez B, Alexandre D, Jegou S, Mounien L, Tollemer H, Chatenet D, Leprince J, Vallarino M, Vaudry H, Chartrel N (2007) Distribution of 26RFa binding sites and GPR103 mRNA in the central nervous system of the rat.
- Buckingham JC, Flower RJ (1997) Lipocortin 1: a second messenger of glucocorticoid action in the hypothalamo-pituitary-adrenocortical axis.
- Calcutt CR, Doggett NS, Spencer PSJ (1971) Modification of the anti-nociceptive activity of morphine by centrally administered ouabain and dopamine.
- Calignano A, La Rana G, Piomelli D (2001) Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide.
- Candeletti S, Ferri S (1990) Antinociceptive profile of intracerebroventricular salmon-calcitonin and calcitonin gene-related peptide in the mouse formalin test.
- Eur J Pharmacol 470:.
- Chapman V, Diaz A, Dickenson AH (1997) Distinct inhibitory effects of spinal endomorphin- 1 and endomorphin-2 on evoked dorsal horn neuronal responses in the rat.
- Charlet A, Lasbennes F, Darbon P, Poisbeau P (2009) Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms.
- Chen JJ, Dymshitz J, Vasko MR (1997) Regulation of opioid receptors in rat sensory neurons in culture.
- Chen SR, Wess J, Pan HL (2005b) Functional activity of the M2 and M4 receptor subtypes in the spinal cord studied with muscarinic acetylcholine receptor knockout mice.
- Chen XH, Geller EB, Rogers TJ, Adler MW (2007) The chemokine CX3CL1/fractalkine interferes with the antinociceptive effect induced by opioid agonists in the periaqueductal grey of rats..
- Brain Res 1153:52–57.
- Cheng JK, Chou RCC, Hwang LL, Chiou LC (2003) Antiallodynic effects of intrathecal orexins in a rat model of postoperative pain.
- Chu CJ, Huang SM, De Petrocellis L, Bisogno T, Ewing SA, Miller JD, Zipkin RE, Daddario N, Appandino G, Di Marzo V, Walker JS (2003) N-Oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia.
- Chu YC, Guan Y, Skinner J, Raja SN, Johns RA, Tao YX (2005) Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund’s adjuvant- induced persistent pain.
- Chung KM, Song DK, Suh HW, Lee MH, Kim YH (1994) Effects of intrathecal or intracere- broventricular pretreatment with pertussis toxin on antinociception induced by beta-endorphin or morphine administered intracerebroventricularly in mice.
- Chung YH, Miyake H, Kamei C, Tasaka K (1984) Analgesic effect of histamine induced by intracerebral injection into mice.
- Ciccarelli R, Ballerini P, Sabatino G, Rathbone MP, D’Onofrio M, Caciagli F, Di Iorio P (2001) Involvement of astrocytes in purine-mediated reparative processes in the brain.
- J Pharmacol Exp Ther Citera G, Arias MA, Maldonado-Cocco JA, Lazaro MA, Rosemffet MG, Brusco LI, Scheines EJ, Cardinalli DP (2000) The effect of melatonin in patients with fibromyalgia: a pilot study.
- Coggeshall RE, Carlton SM (1997) Receptor localization in the mammalian dorsal horn and primary afferent neurons.
- Brain Res Rev 24:28–66.
- Commissiong JW, Galli CL, Neff NH (1978) Differentiation of dopaminergic and noradrenergic neurons in rat spinal-cord.
- Costa A, Smeraldi A, Tassorelli C, Greco R, Nappi G (2005) Effects of acute and chronic restraint stress on nitroglycerin-induced hyperalgesia in rats.
- Cowley MA, Smith RG, Diano S, Tschop M, Pronchuk N, Grove KL, Strasburger CJ, Bidlingmaier M, Esterman M, Heiman ML, Garcia-Segura LM, Nillni EA, Mendez P, Low MJ, Sotonyi P, Friedman JM, Liu HY, Pinto S, Colmers WF, Cone RD, Horvath TL (2003) The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis.
- Crain SM, Shen K-F (1992) After chronic opioid exposure sensory neurons become supersensitive to the excitatory effects of opioid agonists and antagonists as occurs after acute elevation of GM1 ganglioside.
- Brain Res 575:13–24.
- Cridland RA, Henry JL (1988a) Effects of intrathecal administration of neuropeptides on a spinal nociceptive reflex in the rat: VIP, galanin, CGRP, TRH, somatostatin and angiotensin II..
- Cridland RA, Henry JL (1988b) Intrathecal administration of substance P in the rat: spinal transec- tion or morphine blocks the behavioural responses but not the facilitation of the tail flick reflex..
- Cridland RA, Henry JL (1992) Bombesin, neuromedin C and neuromedin B given intrathecally facilitate the tail flick reflex in the rat.
- Cristino L, De Petrocellis L, Pryce G, Baker D, Guglielmotti V, Di Marzo V (2006) Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain.
- mediated tonic inhibition in the dorsal horn of the rat lumbar spinal cord: effects of picrotoxin and strychnine on expression of Fos-like immunoreactivity.
- Csullog E, Joo G, Toth G, Dobos I, Benedek G, Horvath G (2001) Antinociceptive effect of continuous intrathecal administration of endomorphin-1.
- Cui M, Honore P, Zhong C, Gauvin D, Mikusa J, Hernandez G, Chandran P, Gomtsyan A, Brown B, Bayburt EK, Marsh K, Bianchi B, McDonald H, Niforatos W, Neelands TR, Moreland RB, Decker MW, Lee CH, Sullivan JP, Faltynek CR (2006) TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists.
- Eur J Pharmacol 501:87–94.
- Da Motta PG, Veiga APC, Francischi JN, Tatsuo MAKF (2004) Evidence for participation of GABA(A) receptors in a rat model of secondary hyperalgesia.
- Daftary SS, Gore AC (2005) IGF-1 in the brain as a regulator of reproductive neuroendocrine function.
- Daher JB, Souza GEP, D’Orleans-Juste P, Rae GA (2004) Endothelin ETB receptors inhibit artic- ular nociception and priming induced by carrageenan in the rat knee-joint.
- Eur J Pharmacol 496:77–85.
- Damaj MI, Meyer EM, Martin BR (2000) The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model.
- Dawson-Basoa M, Gintzler AR (1997) Involvement of spinal cord delta opiate receptors in the antinociception of gestation and its hormonal simulation.
- Brain Res 757:37–42.
- De Novellis V, Palazzo E, Rossi F, De Petrocellis L, Petrosino S, Guida F, Luongo L, Migliozzi A, Cristino L, Marabese I, Starowicz K, Di Marzo V, Maione S (2008) The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, asso- ciated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats..
- De Petrocellis L, Chu CJ, Moriello AS, Kellner JC, Walker JM, Di Marzo V (2004) Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels.
- De Petrocellis L, Starowicz K, Moriello AS, Vivese M, Orlando P, Di Marzo V (2007) Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB1 receptors and endovanilloids.
- De Petrocellis L, Bisogno T, Davis JB, Pertwee RG, Di Marzo V (2000) Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid recep- tor: inhibitors of anandamide uptake with negligible capsaicin-like activity.
- De Souza EB, Insel TR, Perrin MH, Rivier C, Vale WW, Kuhar MJ (1985) Corticotropin- releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study.
- mary sensory neurons show coexistence of neuropeptides and glucocorticoid receptors in the rat spinal and trigeminal ganglia.
- Delfs JM, Zhu Y, Druhan JP, Aston-Jones G (2000) Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion.
- Desroches J, Guindon J, Lambert C, Beaulieu P (2008) Modulation of the anti-nociceptive effects of 2-arachidonoyl glycerol by peripherally administered FAAH and MGL inhibitors in a neuropathic pain model.
- Di Marzo V, Breivogel C, Bisogno T, Melck D, Patrick G, Tao Q, Szallasi A, Razdan RK, Martin BR (2000a) Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide.
- Di Marzo V, Breivogel CS, Tao Q, Bridgen DT, Razdan RK, Zimmer AM, Zimmer A, Martin BR (2000b) Levels, metabolism, and pharmacological activity of anandamide in CB 1 cannabi- noid receptor knockout mice.
- Di Marzo V, Melck D, Bisogno T, De Petrocellis L (1998) Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action.
- Dirig DM, Yaksh TL (1995) Intrathecal baclofen and muscimol, but not midazolam, are antinoci- ceptive using the rat-formalin model.
- Dirig DM, Yaksh TL (1999) In vitro prostanoid release from spinal cord following periph- eral inflammaton: effects of substance P, NMDA and capsaicin.
- Distrutti E, Sediari L, Mencarelli A, Renga B, Orlandi S, Antonelli E, Roviezzo F, Morelli A, Cirino G, Wallace JL, Fiorucci S (2006a) Evidence that hydrogen sulfide exerts antinocicep- tive effects in the gastrointestinal tract by activating K-ATP channels.
- Dogrul A, Seyrek M (2006) Systemic morphine produce antinociception mediated by spinal 5-HT7, but not 5-HT1A and 5-HT2 receptors in the spinal cord

Xem thử không khả dụng, vui lòng xem tại trang nguồn
hoặc xem Tóm tắt