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Adverse events


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Modified STOP-Bang for predicting perioperative adverse events in the Thai population

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Bang, the incidence of perioperative adverse events was 23.2% in patients with high risk for OSA and 13.8% in patients with low risk (P-value 0.016). While patient with high risk and low risk based on original STOP-Bang had incidence of perioperative adverse events at 22.5 and 14.7% (P-value 0.043). perioperative adverse events stratify risk by modified and original STOP-Bang.

Correlation between immune-related adverse events and therapeutic efects of nivolumab in patients with malignant pleural mesothelioma

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Nivolumab was adminis- tered until disease progression or unacceptable adverse events. Adverse events were assessed according to the National Cancer Institute-Common Toxicity Criteria for Adverse Events (NCI-CTCAE) version 5.0.

Validity and reliability of the simplified Chinese patient-reported outcomes version of the common terminology criteria for adverse events

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Abbreviations: PRO-CTCAE, patient-reported outcomes version of the common terminology criteria for adverse events. US NCI PRO-CTCAE [http://healthcaredelivery.cancer.gov/pro-ctcae/]. Development of the National Cancer Institute's patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCA E). Validity and reliability of the US National Cancer Institute's patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE).

First insight into the whole-genome sequence variations in Mycobacterium bovis BCG-1 (Russia) vaccine seed lots and their progeny clinical isolates from children with BCG-induced adverse events

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However, so far, there is a lack of data on the contribution of BCG genomic diversity to the viability, fitness, and residual virulence of vaccine populations in vivo in the context of the development of BCG- induced adverse events.

Impact of a semi-structured briefing on the management of adverse events in anesthesiology: A randomized pilot study

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Impact of a semi-structured briefing on the management of adverse events in. Background: Human factors research has identified mental models as a key component for the effective sharing and organization of knowledge. The challenge lies in the development and application of tools that help team members to arrive at a shared understanding of a situation. The aim of this study was to assess the influence of a semi-structured briefing on the management of a simulated airway emergency..

Spinal versus general anesthesia for patients undergoing outpatient total knee arthroplasty: A national propensity matched analysis of early postoperative outcomes

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Postoperative events were grouped into serious adverse events (SAE), minor adverse events (MAE), and any adverse events (AE) following the same clas- sification of prior studies on patients undergoing TKA [14, 15]. Minor adverse events included: (1) blood transfusion,. TKA = Total Knee Arthroplasty. Of these, 2,034 patients had surgery with general anesthesia and 3,540 had surgery with spinal anesthesia.

Pediatric premedication: A double-blind randomized trial of dexmedetomidine or ketamine alone versus a combination of dexmedetomidine and ketamine

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No child in group D or group DK experienced respiratory complications during induction.. psychiatric adverse events, and respiratory adverse events were significantly increased in group K during the recovery period and the first 24 h after surgery. Hypoxia occurred in three patients because of irritation from secretions during removal of the LMA. Children in group D and group DK experienced fewer postoperative adverse events overall (P = 0.0152) than those in group K (Table 6)..

A study of anaesthesia-related cardiac arrest from a Chinese tertiary hospital

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The adverse events leading to anaesthesia-related cardiac arrest differ among various studies. Although the respira- tory and airway-related adverse events are considered the major reasons for anaesthesia-related fatal outcomes (death, cardiac arrest) [3, 4], this has not been consistent for all studies. The rates of anaesthesia-related death resulting from airway management events have ranged widely from 7.9 to 80% [12].

Dense hyperthermic intraperitoneal chemotherapy with cisplatin in patients with stage III serous epithelial ovarian cancer: A retrospective study

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In the IDS alone group, no adverse events were recorded in of the 76 patients, and patients were reported to have grade III/IV adverse events. In the IDS plus dense HIPEC group, no adverse events were recorded in of the 121 patients, and patients were reported to have grade III/IV adverse events. No postoperative deaths occurred within 30 days in either group and neither did severe fatal complications in the IDS plus dense HIPEC group..

Safety of intraoperative hypothermia for patients: Meta-analyses of randomized controlled trials and observational studies

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Background: Previous studies have shown that intraoperative hypothermia was associated with higher risks of clinical adverse events, but we found otherwise from recent evidences. This study aims to synthesize the existing evidence evaluating safety of intraoperative hypothermia..

Comparison of monoclonal antibodies targeting CD38, SLAMF7 and PD-1/PD-L1 in combination with Bortezomib/ Immunomodulators plus dexamethasone/ prednisone for the treatment of multiple myeloma: An indirect-comparison Metaanalysis of randomised controlled trials

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Forest plots of the pooled RRs for the grade 3 or higher hematological adverse events (including neutropenia, anemia,. thrombocytopenia, and lymphopenia) of the patients with MM in the MAbs targeting CD38 group versus control group. b Forest plots of the pooled RRs for the grade 3 or higher non-hematological adverse events (including pneumonia, upper respiratory tract infection, diarrhea, and fatigue) of the patients with MM in the MAbs targeting CD38 group versus control group.

Sevoflurane versus PRopofol combined with Remifentanil anesthesia Impact on postoperative Neurologic function in supratentorial Gliomas (SPRING): Protocol for a randomized controlled trial

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All adverse events associated with this trial will be closely monitored until the adverse events are resolved, stable, or confirmed as having no relation to the trial.. Once adverse events occur, they will be immediately re- ported to the research department and to the principal investigator to determine the severity of the adverse events and the consequences of the injury.

Efficacy of premedication with intranasal dexmedetomidine for removal of inhaled foreign bodies in children by flexible fiberoptic bronchoscopy: A randomized, double-blind, placebo-controlled clinical trial

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Oxygen desaturation, body movement, laryngospasm, bronchospasm, and breath-holding are common adverse events during foreign body removal. We hypothesized that intranasal dexmedetomidine at 1 μ g kg − 1 administered 25 min before anesthesia induction can reduce the incidence of adverse events during fiberoptic bronchoscopy under inhalation general anesthesia with sevoflurane..

A phase IA dose-escalation study of PHI101, a new checkpoint kinase 2 inhibitor, for platinum-resistant recurrent ovarian cancer

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In addition, IP safety will be assessed by treatment-emergent adverse events, adverse drug reactions, serious adverse events, seri- ous adverse drug reactions, and adverse events lead- ing to withdrawal. Adverse events will be assessed according to the Common Terminology Cri- teria for Adverse Events (CTCAE) version 5.0 criteria..

Treatment and its side effects in ANCA-associated vasculitides – Study based on POLVAS registry data

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The rate of adverse events as re- lated to the time period when the AAV diagnosis was established is displayed in Fig. Adverse events. The definitions of adverse events were based mainly on clinical assessment (more detailed information with full list of side effects is provided in the Supplementary Table s6. All mentioned cases of infections in the medical documentation were considered as relevant. The highest proportion of patients who developed relapses was in the EGPA subgroup.

Phase II feasibility study of adjuvant chemotherapy with docetaxel/cisplatin/S-1 followed by S-1 for stage III gastric cancer

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Table 2 summarizes the adverse events observed in pa- tients administered adjuvant chemotherapy with DCS.. Table 3 summarizes the adverse events observed in pa- tients administered S-1 adjuvant chemotherapy. Table 2 Adverse events observed in patients administered adjuvant chemotherapy with DCS. Table 3 Adverse events observed in patients administered adjuvant chemotherapy with S-1.

Clinical features as potential prognostic factors in patients treated with nivolumab for highly pretreated metastatic gastric cancer: A multicenter retrospective study

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Associa- tion of immune-related adverse events with clinical benefit in patients with advanced non-small-cell lung cancer treated with nivolumab.. Ricciuti B, Genova C, De Giglio A, Bassanelli M, Dal Bello MG, Metro G, et al. Impact of immune-related adverse events on survival in patients with advanced non-small cell lung cancer treated with nivolumab:. Satoh T, Kang YK, Chao Y, Ryu MH, Kato K, Cheol Chung H, et al.

Intraoperative protective ventilation in patients undergoing major neurosurgical interventions: A randomized clinical trial

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Primary outcomes of the study were intraoperative adverse events, the level of cerebral tension at dura opening and the intraoperative control of PaCO 2. No difference in the rate of intraoperative adverse events was found between groups.

An initial evaluation of the safety of a disposable oscillating positive expiratory pressure device in patients with chronic obstructive pulmonary disease: A short-term pilot study

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No adverse events were recorded during the study or in the follow-up period of 2 weeks. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material.