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Cutaneous melanoma


Tìm thấy 13+ kết quả cho từ khóa "Cutaneous melanoma"

Types of second primary cancer influence overall survival in cutaneous melanoma

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Types of second primary cancer influence overall survival in cutaneous melanoma. Background: Favorable survival in malignant cutaneous melanoma (melanoma) has increased the likelihood of second primary cancer (SPC). We assess the influence of patient characteristics at diagnosis of first melanoma and the type of SPC (second melanoma and other SPC) on overall survival.. Methods: We used the Swedish Cancer Registry data to assess overall survival in melanoma for the period 1990 to 2015.

Achieving integrated self-directed Cancer aftercare (ASICA) for melanoma: How a digital intervention to support total skin self-examination was used by people treated for cutaneous melanoma

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Adults (over the age of 18) who had completed treat- ment within the previous 60 months for a stage 0-2C primary cutaneous melanoma were invited to participate in the ASICA feasibility RCT. Participants were randomized to the ASICA intervention plus standard care, or standard care alone in a 1:1 ratio, minimized on gender and centre, using a. 1 Schematic diagram representing the function of the ASICA intervention.

Recurrent KRAS, KIT and SF3B1 mutations in melanoma of the female genital tract

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In recent years, many of the advances made in the treat- ment of cutaneous melanoma with the aim of improving overall survival, but not readily applicable to mucosal melanomas [5, 6]..

The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma

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Methods: We examined the prognostic significance of somatic APC / CTNNB1 mutations in the Cancer Genome Atlas Project for Skin Cutaneous Melanoma (TCGA-SKCM) database. We assessed APC / CTNNB1 mutations as predictors of response to immunotherapies in a clinicopathologically annotated metastatic patient cohort from three US melanoma centers..

High regional mortality due to malignant melanoma in Eastern Finland may be explained by the increase in aggressive melanoma types

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Incidence trends and clinical-pathological characteristics of invasive cutaneous melanoma from 1980 to 2010 in the canton of Zurich, Switzerland. https://doi.org/10.1097/CMR . https://doi.org/10.1016/j.hoc . https://doi.org/10.1038/modpa thol.3800508..

Chapter 083. Cancer of the Skin (Part 10)

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Albert L et al: Dysplastic melanocytic nevi and cutaneous melanoma:. Atkins MB et al: High-dose recombinant interleukin 2 therapy for patients. Balch CM et al (eds): Cutaneous Melanoma 4th ed. Clark WH Jr et al: The histogenesis and biologic behavior of primary human malignant melanoma of the skin.

Nạo hạch khoeo trong melanom ác di căn hạch

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We present a case of cutaneous melanoma of the fourth toe with inguinal lymph node metastasis earlier and now he had popliteal lymph node metastasis, which is very rare in clinical

Chapter 083. Cancer of the Skin (Part 5)

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Table 83-5 Pigmented Lesions that Must Be Distinguished from Cutaneous Melanoma and Its Precursors. Lesions are usually single, small, 3 mm to <1 cm. Must be distinguished from nodular melanoma.. May be dome-shaped or papillomatous. colors range from flesh colored to very dark brown, with individual nevi being relatively homogeneous in color.. Hemangioma Dome-shaped reddish, purple, blue nodule.. Flat to barely raised brown lesion. Sharp border..

Chapter 097. Paraneoplastic Neurologic Syndromes (Part 9)

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Melanoma-associated retinopathy affects patients with metastatic cutaneous melanoma. Patients develop the acute onset of night blindness and shimmering, flickering, or pulsating photopsias that often progress to visual loss. The ERG demonstrates reduction in the b-wave amplitude. Paraneoplastic optic neuritis and uveitis are very uncommon and can develop in association with encephalomyelitis.. Some patients with paraneoplastic uveitis harbor anti-CV 2 /CRMP5 antibodies..

Chapter 083. Cancer of the Skin (Part 1)

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The challenge is to distinguish cutaneous melanomas, which may be lethal, from the remainder, which with rare exceptions are benign. Examples of malignant and benign pigmented lesions are shown in Fig. Atypical and malignant pigmented lesions. The most common melanoma. Acral lentiginous melanoma is the most common melanoma in blacks, Asians, and Hispanics and occurs as an enlarging hyperpigmented macule or plaque on the palms and soles.

Intralesional injection of rose bengal augments the efficacy of gemcitabine chemotherapy against pancreatic tumors

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Intralesional PV-10 for the treatment of in-transit melanoma metastases-results of a prospective, non-randomized, single center study. Phase 1b study of PV-10 and anti-PD-1 in advanced cutaneous melanoma. T cell mediated immunity after combination therapy with intralesional PV-10 and blockade of the PD-1/PD-L1 pathway in a murine melanoma model

Up-regulation expression and prognostic significance of Syntaxin4 in kidney renal clear cell carcinoma

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The “high” and “low” subgroups were always de- fined based on the mean expression value of STX4 in pan-cancer. survival analysis, it is interesting that STX4 also played a prognostic role in cervical squamous cell carcinoma and endocervical adenocarcinoma, skin cutaneous melanoma, and uveal melanoma (Table 2).. These results suggest that STX4 functions as a tumor promoter in KIRC.. 1 Expression of STX4 mRNA in human KIRC. 2 Prognosis and gene alteration of STX4 in KIRC.

Identification of prognostic immune-related gene signature associated with tumor microenvironment of colorectal cancer

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After the founding of the ESTIMATE logarithm, re- search studies have applied it to prove the efficacy of big-data algorithms on evaluating prostate cancer [18], glioblastoma [19], and cutaneous melanoma [20]. Never- theless, researchers also need to extensively study the value of the ESTIMATE when evaluating stromal and/or immune scores of CRC.

Physician-patient communication of costs and financial burden of cancer and its treatment: A systematic review of clinical guidelines

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Cutaneous melanoma SIGN Brown et al . CAPO Howell et al . Financial burden. Recognition of financial burden Financial burden was recognised in 22 of 27 guidelines . All guidelines from SIGN (n = 5) contained recommendations to assess financial burden in people with cancer. Financial burden was noted in a single NCCN guideline, Distress Management [40], which rec- ommended that clinicians consider ‘financial toxicity’.

Association of advanced age and cancer history with autoimmune disease in melanoma patients: A cross-sectional study

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Melanoma and Non- Cutaneous Cancer lt. Non-Cutaneous Cancer lt. This prevalence appears to vary by tumor type in that patients with a history of non-cutaneous cancers compared to those without a history of non-cutaneous cancers had significantly higher prevalence of autoim- munity. History of having had both melanoma and non- cutaneous cancer exhibited the highest association with autoimmunity compared to the other three study groups (melanoma, non-cutaneous cancer, or no cancer history.

Chapter 083. Cancer of the Skin (Part 6)

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Any pigmented cutaneous lesion that has changed in size or shape or has other features suggestive of malignant melanoma is a candidate for biopsy. The recommended technique is an excisional biopsy, as that facilitates pathologic assessment of the lesion, permits accurate measurement of thickness if the lesion is melanoma, and constitutes treatment if the lesion is benign.

Chapter 056. Cutaneous Drug Reactions (Part 1)

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Cutaneous Drug Reactions. CUTANEOUS DRUG REACTIONS: INTRODUCTION. Cutaneous reactions are among the most frequent adverse reactions to drugs. Most are benign, but a few can be life-threatening. This chapter focuses on adverse cutaneous reactions to drugs other than topical agents;. it covers their incidence, patterns, and pathogenesis and provides some practical guidelines on treatment, assessment of causality, and future utilization of drugs.. USE OF PRESCRIPTION DRUGS IN THE UNITED STATES.

Chapter 056. Cutaneous Drug Reactions (Part 9)

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Antibacterial sulfonamides have a rather high risk of causing cutaneous eruptions and are among the drugs most frequently implicated in SJS and TEN.. The combination of sulfamethoxazole and trimethoprim frequently induces adverse cutaneous reactions in patients with AIDS (Chap.

Adjuvant immunotherapy recommendations for stage III melanoma: Physician and nurse interviews

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Adjuvant immunotherapy. recommendations for stage III melanoma:. physician and nurse interviews. Background: Adjuvant immunotherapy is revolutionising care for patients with resected stage III and IV melanoma.. This study aimed to identify factors physicians and nurses considered regarding adjuvant immunotherapy for melanoma..

Chapter 056. Cutaneous Drug Reactions (Part 2)

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Cutaneous or systemic vasculitis, a relatively rare cutaneous complication of drugs, may also be a result of immune complex deposition (Chap