Tìm thấy 14+ kết quả cho từ khóa "Hematopoietic Stem Cells"
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Some experimental data have suggested that hematopoietic stem cells or other cells mobilized into the circulation by the same factors that mobilize hematopoietic stem cells are capable of playing a role in healing the vascular and tissue damage associated with stroke and myocardial infarction. These data are controversial, and the applicability of a stem-cell approach to nonhematopoietic conditions remains experimental.
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Hematopoietic Stem Cells (Part 1). Hematopoietic Stem Cells. Hematopoietic Stem Cells: Introduction. poiesis: creation) stem cells. If the hematopoietic stem cell is damaged and can no longer function (e.g., due to the nuclear accident at Chernobyl), a person would survive 2–4 weeks in the absence of extraordinary support measures. Stem cells produce tens of billions of blood cells daily from a stem cell pool that is estimated to be only in the hundreds of thousands.
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Hematopoietic Stem Cells (Part 3). Excess Capacity of Hematopoietic Stem Cells. In the absence of disease, one never runs out of hematopoietic stem cells.. Indeed, serial transplantation studies in mice suggest that sufficient stem cells are present to reconstitute several animals in succession, with each animal having normal blood cell production.
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Hematopoietic Stem Cells (Part 2). Developmental Biology of Hematopoietic Stem Cells. These intraembryonic sites engage in sequential order, moving from the genital ridge at a site where the aorta, gonadal tissue, and mesonephros are emerging to the fetal liver and then, in the second trimester, to the bone marrow and spleen.
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Hematopoietic Stem Cells (Part 4). Stem cells are multipotent. SCF, stem cell factor. The hematopoietic stem cell must balance its three potential fates:. memory T and B cells and among stem cells. Self-renewal capacity gives way to differentiation as the only option after cell division when cells leave the stem cell compartment, until they have the opportunity to become memory lymphocytes.
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Bone marrow aspirated from the posterior and anterior iliac crests has traditionally been the source of hematopoietic stem cells for transplantation.. Hematopoietic stem cells circulate in the peripheral blood but in very low concentrations. This has made it possible to harvest adequate numbers of stem cells from the peripheral blood for transplantation.
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Critical functions mediated by activated RTK include proliferation, migration, and enhanced survival of endothelial cells, as well as regulation of the recruitment of perivascular cells and bloodborne circulating endothelial precursors and hematopoietic stem cells to the tumor. Figure 80-10
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Infections in Hematopoietic Stem Cell Transplant (HSCT) Recipients. Transplantation of hematopoietic stem cells from bone marrow or from peripheral or cord blood for cancer, immunodeficiency, or autoimmune disease results in a transient state of complete immunologic incompetence. The reconstitution that follows transplantation has been likened to maturation of the immune system in neonates. Nevertheless, most infections occur in a predictable time frame after transplantation (Table 126-2)..
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Endothelial progenitor cells (EPCs) are immature hematopoietic stem cells which share the same precursor within bone marrow (BM) and are able to induce endo- thelial differentiation in peripheral blood (PB) [9–12].. Mutunga et al. However, it is commonly accepted that EPCs, in BM or immediately cir- culating, express CD133+/CD34+/ VEGFR2 [15]..
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Since AA is probably an organ-specific autoimmune disease in which T cells cause damage to hematopoietic stem cells, the same may be true of PNH, with the specific proviso that the damage spares PNH stem cells. Skewing of the T cell repertoire in patients with PNH supports this notion.
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HCC viết tắt của hepatocarcinoma. helotism (sự) sống nô dịch, (hiện t−ợng) bị bám hút helper T cell tế bào T hỗ trợ. hematopoietic stem cells tế bào gốc tạo máu heme hem. hepatic artery động mạch gan hepatic cell tế bào gan. histiocyte mô bào, tế bào mô. host cell tế bào chủ. human embryonic stem cells tế bào gốc phôi ng−ời. HV viết tắt của Host Vector. idioblast tế bào đặc dị, dị bào. ip-6 viết tắt của Inositol HexaPhosphate. killer T cell tế bào T giết ng−ời kilobase (kb) kilô bazơ.
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Mlinc.89912.1 is principally expressed in BM-MSCs and less in UC and Ad- MSCs, but shows expression in epithelial and endothelial cells. Finally, Mlinc.64225.1 differs from other Mlincs as it is also strongly expressed in keratinocytes, hematopoietic stem cells and epithelial cells (Figure in Additional file 12)..
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In contrast to erythropoietin, but like its myeloid counterparts, granulocyte- and granulocyte-macrophage colony- stimulating factors, thrombopoietin not only enhances the proliferation of its target cells but also enhances the reactivity of their end-stage product, the platelet. In addition to its role in thrombopoiesis, thrombopoietin also enhances the survival of multipotent hematopoietic stem cells..
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VEGF promotes the mobilization and recruitment of circulating endothelial cell precursors (CEPs) and hematopoietic stem cells (HSCs) to tumors where they co-localize and appear to cooperate in neovessel formation. CEPs express VEGFR2, while HSCs express VEGFR1, a receptor for VEGF and PlGF.. Both CEPs and HSCs are derived from a common precursor, the hemangioblast..
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Hematopoietic stem cells (HSCs) (Chap.
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These isolated stem cells, e.g., hematopoietic stem (HS) cells, can be studied in detail and used in clinical applications, such as bone marrow transplantation (Chap. However, the lack of specific cell-surface markers for other types of stem cells has made it difficult to isolate them in large quantities.. Alternatively, putative stem cells have been isolated from a variety of tissues as side population (SP) cells using fluorescence-activated cell sorting after staining with Hoechst 33342 dye.
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INHIBITED GROWTH OF MESENCHYMAL STEM CELLS UNDER SIMULATED MICROGRAVITY. This study aimed to estimate the effects of simulated microgravity (SMG) on mesenchymal stem cells (MSCs). The 3D clinostat was applied to induce to simulated microgravity on MSC. The results showed that the MSC density in control group was higher than the SMG group.
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In vitro differentiation of mesenchymal stem cells into mesangial cells when co-cultured with injured mesangial cells.
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Keywords: Extracellular vesicles, umbilical cord-derived mesenchymal stem cells, microRNAs.. Mesenchymal stem cells (MSCs) are pluripotent adult stem cells isolated from mature tissues and able to renew and. E-mail address: [email protected] https://doi.org vnunst.5302.
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Stichoposide D stimulates caspase-3 activity in NTERA-2 cancer stem cells after 24 hours of treatment at various concentrations. *P<0.05. Stichoposide D impacts on cell-cycle of NTERA-2 cancer stem cell. (B) stichoposide D at 0,5 µM. (C) stichoposide D at 1 µM after 24 hours incubation. Stichoposide D affects surface markers on cancer stem cells.