Tìm thấy 13+ kết quả cho từ khóa "In silico analysis"
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A detailed in silico analysis of secondary metabolite biosynthesis clusters in the genome of the broad host range plant pathogenic fungus Sclerotinia sclerotiorum. Secondary metabolites are known to play important roles in the virulence of plant pathogens, but little is known about the secondary metabolite repertoire of S. In this study, we predicted secondary metabolite biosynthetic gene clusters in the genome of S.
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APAF1 plays a key role in the intrinsic or mitochondrial pathway of apoptosis. Therefore, APAF1 is related to regulation and function in cell death (Shakeri et al., 2017). The purpose of this study was to predict deleterious/damaging SNPs in the APAF1 gene via in silico analysis. In silico analysis of the missense SNPs was carried out by using publicly available online software tools.
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Such in vitro practical verification of new potential cis-element function is usually performed using plant transformation techniques and subsequent transgene expression analysis (Hernandez-Garcia et al., 2014).. Currently, available databases, for example PLACE (Higo et al., 1999) and PLANTCARE (Lescot et al., 2002), contain a collection of various cis-regulatory sequences described in earlier studies that can be used as a tool for in silico analysis of unknown promoter sequences..
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This SCS was located near the end of the hydrophobic stretch leaving relatively few hydrophobic amino acids to act as an anchor. ellipsiformis F-ORF was lo- calized as extracellular based on the in silico analysis and not predicted to occur in any of the locations identi- fied through immunostaining [13]. DUI), and (3) they are produced in the. [75], with the exception of the position of Echyridella menziesii..
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Restivo, Isolation and characterization of two cDNA clones encoding for glutamate dehydrogenase in Nicotiana plumbaginifolia, Plant Cell Physiol . In Silico Analysis of Glutamate Dehydrogenase Gene Family in Soybean (Glycine max L.). Abstract: Glutamate dehydrogenase (GDH, EC are the enzymes which catalyze reversible deamination reaction of L-glutamate to 2-oxoglutarate or -ketoglutarate (-KG)
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Analysis of the largest tandemly repeated DNA families in the human genome. Initial sequencing and comparative analysis of the mouse genome. Recent amplification of the kangaroo endogenous retrovirus, KERV, limited to the centromere. On the sequencing of the human genome. The hierarchy of the 3D genome
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Of the 1259 potential FOXO targets expressed in at least one wing morph, 11 of 46 flight muscle genes were identified as the target genes (P-value = 0.014 by hypergeometric test) (see Additional file 1: Table S9). 4 Identification of the genome-wide putative target genes of FOXO. d The venn diagram of the putative target genes of FOXO identified from ChIP-seq and genome-wide in silico analysis, respectively. e-f The enrichment analysis of the FOXO putative target genes were performed based on GO
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Nuclear mitochondrial sequences (NUMTs) identified in the mouse genome.. Average nucleotide coverage of the mito-piRNAs in mt-tRNAs.. In silico analysis of the mitochondrial localization of mouse PIWI protein isoforms. Description of the small RNA-Seq datasets in 3T3-L1 cells obtained from the GEO database. Non-coding RNAs: multi-tasking molecules in the cell. PIWI proteins and PIWI-interacting RNAs in the soma. Detection of PIWI and piRNAs in the mitochondria of mammalian cancer cells.
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In order to further distinguish genomic differences underlying the divergent hydrogenogenic capacities of the four P. In silico analysis of the operon structure of this locus using FgenesB [27] showed that the genes form part of three distinct operons, cooCSF, phcABCDEFGHIJ and phcKL, in all four strains (Fig.
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Based on in silico analysis, the PSMD4 promoter contains many putative HIF-1 binding sites and –79 sites. To investigate the effect of the HIF1α protein on PSMD4 promoter activity, PC3 cells were transfected with truncated PSMD4 promoter construct pMET_. and pMET_PSMD respectively in the absence or presence of CoCl 2.
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Intersection of the DEG datasets identified 739 genes in- volved in this process (Fig. 1 Histological analyses of the spleen. Immune response genes are inhibited in the spleen during hypoxia. In silico analysis of immune cell populations demonstrated inhibition of the immune response. Tran- scriptomic analysis of the large yellow croaker also showed that immune response genes were downregu- lated in spleen [57]. Animals stayed in the chamber for the duration of the experiment.
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The RepeatExplorer pipeline, used for in silico analysis, has been widely used in the study of repetitive DNA in plants, and publications are increasing.
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In contrast, some researchers have identified the phylogenic origin of this family with only 1 DNA binding domain (Du et al., 2009). Du et al. The molecular phylogenetic analysis revealed that all eukaryotes contained at least 1 member of the MYB protein family (Wilkins et al., 2009). The first member, known as V-MYB, was identified in virus (Wilkins et al., 2009). It was suggested that MYB genes originated from vertebrate genes (Du et al., 2009).
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In Silico Analysis of Osa-miR164 Gene Family in Rice (Oryza Sativa). By using bioinformatics approach, we analyzed sequences of all osa-miR164s belonging to rice miR164 family, evaluated the expression profile of osa-miR164 under different stress conditions, predicted cis-regulatory elements on osa-miR164 gene promoters, and simultaneously predicted miR164-targeted genes and their expressions.
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In silico analysis of bacterial translation factors reveal distinct translation event specific pI values. In this regard, we asked the question about how similar are those translation factors to each other from a wide variety of bacteria?
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The in-silico analysis carried out here highlights the strong selective pressure for the expansion in copy number of the chromosome 10 GP63 genes within Leishmania species, and in particular in the Viannia and Sauroleishmania sub- genera. The increased number of the chromosome 10 GP63 genes in different Leishmania species evolved inde- pendently generating a wide range of paralogs, which display sequence variations and may be generated by recombination.
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In silico comparative proteomic analysis of enzymes involved in fatty acid biosynthesis in castor bean (Ricinus communis) and soybean (Glycine max). Efforts have been made in different countries for the introduction and promotion of biodiesel (Carraretto et al., 2004).. Ricinus communis and Glycine max, with varying amounts of oil content.
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A phylogenetic analysis of the identified AGO-like sequences revealed that the R. irre- gularis, we wondered if some of the identified R. irregularis AGO-like proteins were related with those of the animal Piwi-like group or with the ones specific of the C. The associ- ation of the last three RdRp proteins to the clade containing M. thaliana in the analysis, no difference in the structure of the tree topology was de- tected (Additional file 1: Figure S2)..
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Sex-linked markers in the north American green frog (Rana clamitans) developed using DArTseq provide early insight into sex chromosome evolution. Breaking RAD: an evaluation of the utility of restriction site-associated DNA sequencing for genome scans of adaptation. Representational difference analysis as a tool in the search for new tumor suppressor genes. In silico identification of potential therapeutic targets in the human pathogen helicobacter pylori.
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In silico characterization of a novel putative aerotaxis chemosensory system in the. Results: Here we report the in silico characterization of a putative energy taxis cluster, Cc-5, which is present in only one amongst 34 known and sequenced myxobacterial genomes, Corallococcus coralloides. In addition, we propose that this energy taxis cluster is involved in oxygen sensing, suggesting that C.