Có 20+ tài liệu thuộc chủ đề "Journal of Biology"
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doi:10.3906/biy-1808-34. Consumers today are quite well aware of the importance of healthy food for their health. Probiotics are defined as live microorganisms, which have a positive effect on human health (Begley et al., 2006). Among them, the representatives of the genus Lactobacillus are used predominantly in different probiotic products due to their greater resistance to low pH and better adaptation...
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It has been shown that CSCs are resistant to treatment and that they play a crucial role in recurrence (Easwaran et al., 2014. Toh et al., 2017). Therefore, new therapy regimes which include epigenetic modifiers have begun assessment in clinical trials (Samavat et al., 2016. Azad et al., 2017. Von Hoff et al., 2018). Kagara et al., 2012;. Vedeld et...
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The enzyme transfers GlcNAc-phosphate to the oligosaccharide units of lysosomal enzyme precursors (Kudo et al., 2006. Wang et al., 2018). However, in ML-II, these enzymes are not trafficked properly to the lysosomes and instead leak out of the cells, causing massive accumulation of undigested substrates in lysosomes (Mazrier et al., 2003).. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE,...
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Chemotherapeutic agents used in the treatment of various types of cancer have side effects such as ototoxicity and nephrotoxicity. The toxic effects of these antineoplastic drugs can be ignored because of their potency of improving an individual’s chances of survival by impairing mitosis of fast-dividing cancer cells (Kilic et al., 2015a). which is used against various forms of solid cancers...
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Examining the involvement of Slx5 in the apoptotic response to chronic activation of the spindle assembly checkpoint. In the presence of improper attachment(s), SAC activation leads to a cell cycle arrest in metaphase until the attachment error is corrected before the cell proceeds to anaphase, thus prevents aneuploidy in daughter cells (Lara-Gonzalez et al., 2012). Since SAC activation prevents cell...
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One of the well-known examples of bacterial biomineralization is calcium carbonate (CaCO 3 ) precipitation and it is well established that many bacteria have the capability of producing various forms of CaCO 3 in a different environment. Although anhydrous polymorphs such as calcite, aragonite, and vaterite and hydrated crystalline forms such as monohydrocalcite and ikaite are produced as a result...
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According to the 2018 data of the American Cancer Research Institute, colorectal cancer is the third most frequent cancer in males and second most frequent in females. Although the methods of administration and the areas of the tumor for which they are applied are different and limited, the research and treatment methods that have boron as a common feature are...
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doi:10.3906/biy-1904-37. The maintenance of the epidermis is provided by sustained proliferation and differentiation of the keratinocyte stem cells localized to the basal layer of the epidermis (Fuchs and Nowak, 2008;. (Romano et al., 2007. Marinari et al., 2009. Thomason et al., 2010. Mitchell et al., 2012).. RIPK4 is one of the major determinants of keratinocyte differentiation, mutations of which were...
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Bone tissue engineering researches are based on the induction of the regeneration of a new functional bone by using the interactive combination of biomaterials, cells, and biosignalling molecules (Amini et al., 2012). Bone marrow-derived mesenchymal stem cells are great sources for the application of tissue engineering because of their capability to differentiate into many different kinds of cells including the...
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A magnetic affinity approach to identify plant GABA-binding proteins. Podlesakova et al., 2019). Bettler et al., 2004). In addition, GABA is a significant component of the free amino acid pool in plants and it is present in almost all organs. The intercellular GABA content can be increased quickly in response to biotic and abiotic stresses, such as cold, drought, salinity,...
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Despite recent progress in early detection and new therapeutic strategies, the rate of incidence is increasing worldwide (Bray et al., 2018).. Triple-negative breast cancer (TNBC), a subtype of breast cancer, is characterized by the lack of estrogen, progesterone, and human epidermal receptors (Brenton et al., 2005). TNBC is a biologically aggressive type of breast cancer with a poor survival rate...
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One of the primary aims of genomics studies is to characterize genetic variations and associate them with phenotypes including genetic diseases. Recently there has been substantial progress in detecting various types of genetic variations (Shendure et al., 2017). While many different types of genetic variations such as single-nucleotide polymorphisms (SNPs), copy number variation (CNV), and structural variation (SV) have been...
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doi:10.3906/biy-1904-59. MicroRNA prediction based on 3D graphical representation of RNA secondary structures. Not only the sequences but also the struc- tures of the RNA molecules have great importance. There are three main levels of RNA structure: primary (base se- quence), secondary (based on base pairs, e.g., hairpins or the cloverleaf structure of transfer RNA (tRNA. and ter- tiary (interactions between...
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It is composed of cancer- related structures in the head and neck, including the lips, mouth, nasal cavity, paranasal sinuses, salivary glands, oropharynx, nasopharynx, hypopharynx, and larynx (Jemal et al., 2007). The mortality rate is 0.53, and death is three times more frequent in men (Pehlivan et al., 2008).. metastasis is still the main cause of death in HNC patients...
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Attwooll et al., 2004). Proteins E2F1 through E2F6 also contain a conserved domain responsible for binding to dimerization partner proteins (de Brucin et al., 2003. Di Stefano et al., 2003). Attwooll et al., 2004. Cam et al., 2004. Bieda et al., 2006. Zalmas et al., 2008;. Chen et al., 2009). Pathways regulated by E2Fs are clearly implicated in breast cancer...
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sodium-(O-[(2,6- dichlorophenyl)-amino]-phenyl)-acetate) acts as a potent cyclooxygenase (COX) inhibitor, reducing arachidonic acid release and formation of prostaglandins (Capone et al., 2007). However, it has been reported that in adults, taking DS as a medication may produce some side effects such as serious bleeding in the upper gastrointestinal system, dysfunction in the cardiovascular system, failure in the functions of platelets, and...
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Salt stress is one of the primary abiotic stresses that affect plant growth and global crop yields (Miyazaki et al., 2007;. Song et al., 2011). Simultaneously, soil salinization causes a decline in land productivity and seriously threatens the sustainable development of agriculture and forestry (Bandehagh et al., 2011. Kosová et al., 2011). Soni et al., 2015). tags for relative and...
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Commonly known as French marigold, it is found abundantly in tropical regions and is also cultivated in Pakistan (Priyanka et al., 2013). patula has long been used in relieving the complaints of cough, dysentery, liver ailments, stomach ailments, and rheumatism (Vasilenko et al., 1990). Its leaves are useful in relieving muscle- and kidney-associated pain (Rahman et al., 2013). The antioxidant...
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doi:10.3906/biy-1902-64. A new Helicoverpa armigera Nucleopolyhedrovirus isolate from Heliothis peltigera (Denis &. Schiffermuller) is one of the most serious pests infesting various economic crops such as safflower, cotton, soybean, corn, bean, and herbs (Manjunath et al., 1976. however, as a result of climatic changes, such as global warming, it is currently becoming a major problem in the European countries (Ragionieri...
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Liu et al., 2016).. recruit other immune cells to the infection site in order to eliminate the trigger and reestablish tissue homeostasis (He et al., 2015. Jorgensen et al., 2016).. the NFκB pathway or type I IFN pathway, in the case of endosomal TLRs (Bauernfeind et al., 2009). Muñoz-Planillo et al., 2013). Iyer et al.,. Although the activation of the...