« Home « Kết quả tìm kiếm

Pharmaceutical formulations


Tìm thấy 12+ kết quả cho từ khóa "Pharmaceutical formulations"

A novel fluorimetric method for determination of pseudoephedrine hydrochloride in pharmaceutical formulations and blood serum

tailieu.vn

In the present paper, we report a very sensitive, simple, fast, and inexpensive method for the determination of PSH in pharmaceutical formulations and serum samples. PSH dissociates Rh6G-Au NPs complexes and releases Rh6G molecules into the reaction media, which subsequently recovers fluorescence of Rh6G quenched by fluorescence energy transfer (FRET) between Rh6G and Au nanoparticles. The developed method was used for the determination of PSH in pharmaceutical formulations and serum samples.

Spectrophotometric determination of 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors in pharmaceutical preparations

tailieu.vn

Moreover, the proposed methods are less expensive than the application of HPLC techniques. 20−30 The described methods are suitable for the determination of statins in pharmaceutical formulations without interference from excipients and could be easily applied in quality control laboratories for the routine analysis of these drugs in raw material and pharmaceutical formulations.. The Chemistry of the Cyano Group, Interscience, New York, 1970.

Voltammetric determination of glycopyrrolate in a pharmaceutical formulation

tailieu.vn

Several parameters that affect the sensitivity of these methods were optimized for the quantitation of glycopyrrolate. 0.9990 in the range of 0.1–0.5 mg/mL. 2,3 The standard techniques that are currently used for the determination of drugs in biological fluids, bulk form, and pharmaceutical formulations are based on chromatographic or spectroscopic assays. 2 Such techniques for the determination of drug concentrations are necessary in a clinical environment to provide appropriate drug levels and

Development and validation of an HPLC method for determination of rofecoxib in bovine serum albumin microspheres

tailieu.vn

LC determination of rofecoxib in bulk and pharmaceutical formulations. Journal of Pharmaceutical and Biomedical Analysis 2001. US Department of Health and Human Services, Food and Drug Administration Center for Drug Evaluation and Research (CDER), Guidance for Industry, Q2B Validation of Analytical Procedures: Methodology, 1996.. Some practical examples of method validation in the analytical laboratory. Current HPLC method for assay of nano drug delivery systems.

Simultaneous determination of azithromycin and levofloxacin in pharmaceuticals by charge transfer complexation with alizarin red S using an absorption-factor

tailieu.vn

The method was successfully applied for the simultaneous determination of these antibacterial drugs from their synthetic mixtures and pharmaceutical formulations with no interference from excipients.. 1 Its antimicrobial spectrum is similar to that of erythromycin, but is more effective against certain bacteria, 2,3 and is one of the world’s best-selling antibiotics.

Application of a pencil graphite electrode for voltammetric simultaneous determination of ascorbic acid, norepinephrine, and uric acid in real samples

tailieu.vn

Similar to the previous studies 24 − 32 on the electroanalytical application of pencil leads, this study aims to develop a new, rapid, and highly sensitive electroanalytical method for the simultaneous determination of AA, NE, and UA, a PGE using DPV that is possible to be adopted in both urine and pharmaceutical formulations.. Electrochemical behaviors of AA, NE, and UA at the PGE.

Detection of alkanolamines in liquid cement grinding aids by HPLC coupled with evaporative light scattering detector

tailieu.vn

Journal of Pharmaceutical Analysis 2013. Determination of azithromycin in raw materials and pharmaceutical formulations by HPLC coupled with an evaporative light scattering detector. Asian Journal of Pharmaceutical Sciences 2014. steroidal saponins using HPLC-ELSD method

Novel voltammetric investigation of dipyridamole at a disposable pencil graphite electrode

tailieu.vn

When compared with data previously published in the literature regarding the voltammetric determi- nation of DIP (Table 2), the DPV at the PGE method developed in the present study does not have a very low LOD, but this aspect is not so important when the method is applied for the determination of the active principle in pharmaceutical formulations.

Development of a spiramycin sensor based on adsorptive stripping linear sweep voltammetry and its application for the determination of spiramycin in chicken egg samples

tailieu.vn

Sensitive and selective spectrophotometric determination of spiramycin in pure form and in pharmaceutical formulations.. Separation and determination of the macrolide antibiotics (erythromycin, spiramycin and oleandomycin). doi: 10.1002/. Cyclic voltammetry and determination of spiramycin at water/oil ınterfaces. Research on electrochemical behavior of spiramycin.

Voltammetric analysis of disulfiram in pharmaceuticals with a cyclic renewable silver amalgam film electrode

tailieu.vn

The present study showed that SWCSV along with a Hg(Ag)FE electrode can be successfully used to determi- nate the disulfiram content in its commercial pharmaceutical formulations. Optimization of the experimental parameters yielded a detection limit of mol L − 1 and linear range of mol L − 1 .

Synthesis of neodymium-iron nanoperovskite for sensing applications of an antiallergic drug

tailieu.vn

The proposed sensor was evaluated for the determination of ketotifen in real samples of human urine and blood serum and pharmaceutical formulations. These analyses were undertaken to examine the applicability of the proposed method for analysis. In the case of blood serum, the linear calibration. The accuracy and precision of the proposed method in urine analysis were evaluated by choosing five different concentrations and repeating them five times (Table 3).

Synthesis of acetamide derivatives of 1,2,4-triazole bearing azinane and their binding interactions with bovine serum albumin using spectroscopic techniques

tailieu.vn

These findings may provide basic data on the binding mechanism of the synthesized triazole derivatives with blood carrier proteins, which can be helpful for the security of human health when applied in pharmaceutical formulations.. N -(substituted nitrophenylsulfonyl)piperidin-4-yl)-4-phenyl-4H -1,2,4-triazol-3-ylthio)acetamides (8a–8i. Different aryl substitutions for 8a–8i..

Pharmaceutical Coating Technology (Part 16)

tailieu.vn

A PHARMACEUTICAL FILM COATING PUBLICATIONS BIBLIOGRAPHY This chapter contains a comprehensive listing of research papers, reviews, book chapters and theses covering the subject of pharmaceutical film coating. Film-coating materials (polymers, additives, formulation—including solutions and suspension properties).

HPLC for Pharmaceutical Scientists 2007 (Part 16)

tailieu.vn

Supple- mentary to this prerequisite is the identification of the commercial production site or launch site where the pharmaceutical dosage form will be manufac- tured. 16.2.2 Availability of the Finalized Pharmaceutical Active Ingredient (API), Known Degradation Products, By-products and Reference Standards Besides the existence of validated HPLC methods, the availability of a final- ized API synthetic scheme and optimized formulations is another prerequisite for ensuring a successful transfer of

Determination of N-acetylcysteine in the presence of ciprofloxacin or levofloxacin in microparticulate dry powder inhalers

tailieu.vn

Since CP, LV, and NAC, as active pharmaceutical substances, are frequently formulated together, the ability to analyze these three substances at the same time with a single method is an important innovation that accelerates pharmaceutical studies, and also their monitoring in pharmaceutical formulation during stability studies, which is an obligatory regulatory requirement.

Efficiency of certain clodinafop-propargyl formulations in controlling annual grassy weeds in wheat

tailieu.vn

Efficiency of certain clodinafop-propargyl formulations in controlling annual grassy weeds in wheat. Weed control;. Abstract Field experiments were conducted in 2009–2010 and 2010–2011 seasons to evaluate the effect of four post-emergence clodinafop-propargyl formulations (Topic 15% WP, Akopic 24% EC, Current 24% EC and Herstop 15% WP) and hand weeding for controlling annual grassy weeds in wheat fields.

Research on film coating formulation of sustained release pellets of verapamil hydrochloride

tailieu.vn

Specifically: CT16 and CT17 with large DEP proportions reduced pharmaceutical substance release rate more clearly than CT13. These two formulations released less than 80% pharmaceutical substance after 8 hours. In the case of TEC plasticizer, a hydrophilic plasticizer, higher proportion of TEC would result in higher rate of pharmaceutical substance release.

Simultaneous determination of dexpanthenol, lidocaine hydrochloride, and mepyramine maleate in combined pharmaceutical gel by capillary electrophoresis

tailieu.vn

Simultaneous determination of dexpanthenol, lidocaine hydrochloride, and mepyramine maleate in combined pharmaceutical gel by capillary electrophoresis. Abstract: A new capillary electrophoresis method was developed for the simultaneous determination of dexpanthenol (DEX), lidocaine (LID), and mepyramine (MEP) in pharmaceutical preparations. The best results were obtained using 20 mM (pH 3.0) phosphate buffer as the background electrolyte.

Formulations and quality characterization of gluten-free Egyptian balady flat bread

tailieu.vn

Rojas et al., 1999). 0.05) was evident in the staling of con- trol balady flat bread and other GFBFB formulations. Brennan et al. Similar observations are in accordance with Guarda et al. Sensory characteristics of gluten-free balady flat breads The sensory evaluation data demonstrated that GFBFB did not vary significantly in all of the sensory characteristic evalu- ation (Table 6).

Pharmaceutical Coating Technology (Part 2)

tailieu.vn

Formulations intended for conventional film coating can be further modified to enhance swelling and permeability by the incorporation of materials such as water soluble cellulose ethers, and starches in order to ensure complete disintegration/dissolution of the film..