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Regulatory roles

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Comparative transcriptome analysis uncovers regulatory roles of long noncoding RNAs involved in resistance to powdery mildew in melon

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However, there is lim- ited information about the roles of lncRNAs and their regulatory mechanism in resisting to PM infection in plants. In the present study, high-throughput RNA-seq and comparative transcriptome analysis were performed to identify PM- responsive lncRNAs from the leaves of PM-resistant and. In total, 11,612 lncRNAs were finally discovered.

Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

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Therefore, we can draw the conclusion that the regulatory roles of lysine acetylation in DON biosynthesis in F.. graminearum results from the positive and negative regulation of the related genes. The study would be a foundation to insight into the regulatory mechanism of lysine acetylation on DON biosynthesis.. In addition to the severe yield loss and quality damage, the pathogen produces trichothecene-type mycotoxins, such as deoxy- nivalenol (DON) in the infected tissue.

Maize transposable elements contribute to long non-coding RNAs that are regulatory hubs for abiotic stress response

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Clearly additional work is required to prove that these TE-lncRNAs function as hypothesized in abiotic re- sponse, but their centrality in co-expression modules is nonetheless an intriguing result that is consistent with previous findings showing that most lncRNAs are de- rived from TEs [7] and that lncRNAs can play central regulatory roles in plant and animal development [63].. Of the Illumina datasets, 89 represented polyA+. All of the 129 datasets were used for lncRNA dis- covery.

Integrated small RNA and Degradome sequencing provide insights into salt tolerance in sesame (Sesamum indicum L.)

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Previous studies have shown that NAC family members (NAC1, NAC4, NAC13 and NAC17) play important regulatory roles in plant responses to salt stress via activating the expres- sion of stress-responsive genes [38–41]. In our present work, we found that the level of NAC 21 and NAC79 mRNA increased compared with the decrease in miR164d and miR164e in sesame under salt stress, sug- gesting their important roles in sesame (Fig.

Genome-wide analysis of SET-domain group histone methyltransferases in apple reveals their role in development and stress responses

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Generally, this work presents a comprehensive analysis of SDG genes in apple and pro- vides a basis for future work to explore the regulatory roles of MdSDGs in apple development and stress responses.. The evolutionary analysis of MdSDG synteny and collinearity in the apple genome is shown in Fig.

Deciphering the miRNA transcriptome of breast muscle from the embryonic to posthatching periods in chickens

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These genetic factors co-operate with each other to ensure normal development of skeletal muscle.. miRNAs have been found to have important regulatory roles during skeletal muscle development [3]. Full list of author information is available at the end of the article. abundantly expressed in muscle tissue and contribute to muscle development. Skeletal muscle development is a multi- step process that includes myofiber formation and hypertrophy.

Genome-wide identification and transcript analysis of TCP transcription factors in grapevine

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These observations sug- gested that these miRNA-targeted VvTCP genes were likely to perform similar roles in leaf and flower develop- ment in grapevine to those of the Arabidopsis homologs.. These findings suggested that these Class I VvTCP genes might play various regulatory roles at multiple growth and development process. Potential roles of VvTCP genes during berry development and ripening.

Expression profiling of WD40 family genes including DDB1- and CUL4- associated factor (DCAF) genes in mice and human suggests important regulatory roles in testicular development and spermatogenesis

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Dependence of spermatogenesis on proteolytic and non-proteolytic ac- tions of protein ubiquitination is well documented and many E3 ligases have be shown to play vital roles in many of the cellular and molecular process required for the production of mature spermatozoa .

Genome-wide identification, phylogeny, and expression analysis of the SBP-box gene family in Euphorbiaceae

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MiR156 plays the most important regulatory roles out of almost all the miRNAs that regulate SBP genes (with target sites located either in the coding re- gion [CDS] or 3′ untranslated region [UTR]) [20, 21]. It has been predicted that 10 of the 16 AtSPL genes are po- tential targets of miR156/157 (collectively known as miR156). Due to regulation by miRNAs, some SBP genes are involved in complex regulatory processes.

Activation of metabolic and stress responses during subtoxic expression of the type I toxin hok in Erwinia amylovora

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Although it is still unclear whether Hok exhibits any direct regulatory roles, the overlapping downstream transcriptional effects due to hok induction and other membrane perturbing agents suggest that for- mation of membrane pore is at least one of the main reasons for the transcriptomic changes observed during hok induction.. A working model summarizing the effects of hok in- duced at subtoxic or toxic levels in E.

Transcriptome-wide N6-methyladenosine modification profiling of long non-coding RNAs during replication of Marek’s disease virus in vitro

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As one of the most abundant and conserved RNA modifications, m 6 A is known to be involved in various viral infections, suggesting an important regulatory role in viral replication and pathogenesis [16]. Alter- ations in the m 6 A signature of lncRNAs suggests that m 6 A modifications may play important regulatory roles during MDV replication.. Transcriptome-wide m 6 A modifications in lncRNAs after Md5 (a very virulent MDV strain) infection.

Physiological and transcriptomic analyses reveal the roles of secondary metabolism in the adaptive responses of Stylosanthes to manganese toxicity

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roles in secondary metabolism in stylo during Mn exposure, which deserves further study..

Regression trees for regulatory element identification

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Regulatory ele- ments MSE and URS1 are known to play active roles in the regulation of gene expression during sporulation (Chu et al., 1998). Another motif, MCB, is one of the highly scored motifs found in (Bussemaker et al., 2001). These combinations of motifs are consistent with those reported by Pilpel et al. From the tree in. Figure 2, we find one motif combination—mRRPE(M3A) and PAC—which is among the findings of Pilpel et al.

Evolution of cis- and trans-regulatory divergence in the chicken genome between two contrasting breeds analyzed using three tissue types at one-day-old

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Both cis- and trans-regulatory variation are play key roles in phenotypic variation [1, 8–10]. Therefore, it is critical to investigate gene regulatory divergence in birds.. The rapid change under domestication offers a unique model for revealing the relative importance of the cis- and trans-regulatory variation underlying phenotypic change.

Transcriptome analysis of the brain provides insights into the regulatory mechanism for Coilia nasus migration

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Traditionally, research on the effects of temperature and salinity as environmental stressors in fish has been carried out in the liver and gills due to the pivotal roles of these organs in energy supply and osmoregulation.. Recent studies that investigated the strengthening of the brain regulatory function in response to salinity and cold stress have indicated that the expression of hormones, neurotransmitters, receptors, and key regulatory proteins was upregulated [13–18]. Xu et al.

LncRNAs and their regulatory networks in breast muscle tissue of Chinese Gushi chickens during late postnatal development

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Although many genes play important roles in chicken muscle growth, studies have shown that only a small percentage (1–2%) of the genome encodes proteins in mammals, and tens of thousands of intergenic sites are transcribed into noncoding RNA [9]. In the past few years, regulatory RNAs, such as miRNAs, piRNAs, snoRNAs, and long noncoding RNAs (lncRNAs), have appeared to play roles in many important biological processes [10].

A comparative analysis of heart microRNAs in vertebrates brings novel insights into the evolution of genetic regulatory networks

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In fact, miR-26 may play pivotal roles in the heart (reviewed by [69. In this sense, miR-26 should be the focus of further experiments to elucidate its functional roles in the heart GRN of vertebrates..

Globally learning gene regulatory networks based on hidden atomic regulators from transcriptomic big data

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Gene regulatory networks (GRNs) play fundamental and central roles in response to endogenous or exogenous stimuli for maintaining the viability and plasticity of cells [1, 2]. China Full list of author information is available at the end of the article.

Improved recovery of cell-cycle gene expression in Saccharomyces cerevisiae from regulatory interactions in multiple omics data

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Nonetheless, the Deletion data allows for the identification of known cell cycle reg- ulators not found in the ChIP network, particular SFP 1 [71] that also plays roles in regulation of ribosomes in response to stress [36, 47] (green outline, Fig.

Migration Roles and Responsibilities

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Migration Roles and Responsibilities. Help your migration staff—and other TechRepublic. members—understand their roles when migrating from NT to 2003. Given the size of most migration projects, one of the first questions that you’ll have to answer from your team will be “Which part of this is my responsibility?” Giving everyone on your team a clear picture of what’s expected of them from the beginning is one way to focus team members on a particular task..