Có 22+ tài liệu thuộc chủ đề "harrison intenal medicine"
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Disorders of Granulocytes and Monocytes. Metabolic disorders—ketoacidosis, acute renal failure, eclampsia, acute poisoning. Inherited and acquired abnormalities of phagocyte function are listed in Table 61-3. The resulting diseases are best considered in terms of the functional defects of adherence, chemotaxis, and microbicidal activity. features of the important inherited disorders of phagocyte function are shown in Table 61-4.. Table 61-3 Types...
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Disorders of Granulocytes and Monocytes. Disorders of Adhesion. Two main types of leukocyte adhesion deficiency (LAD) have been described, LAD 1 and LAD 2. Both are autosomal recessive traits and result in the inability of neutrophils to exit the circulation to sites of infection, leading to leukocytosis and increased susceptibility to infection (Fig. Patients with LAD 1 have mutations in...