« Home « Kết quả tìm kiếm

Cytotoxic activities

Tìm thấy 12+ kết quả cho từ khóa "Cytotoxic activities"

Phytochemical characterisation of Phlomis linearis Boiss. & Bal and screening for anticholinesterase, antiamylase, antimicrobial, and cytotoxic properties

tailieu.vn

MTT test was evaluated to see cytotoxic activity of the extracts of P. Also, the cytotoxic activities of extracts were studied against NIH3T3 cells, and to determine the selectivity of the extracts towards carcinogenic cell lines. The IC 50 values of the extracts were determined against cell lines in Table 6.. Hence, cytotoxic effect of the extracts against NIH3T3 cell line was tested. Cytotoxic activity of P. In another study, cytotoxic activity of the 80% MeOH extracts.

Investigation of cytotoxic activity of cyanobacterial strains isolated from water and soil samples collected in Hanoi

tailieu.vn

In our previous study, the MeOH extracts of three nostocacean strains demonstrated cytotoxic activities against MCF7 and HCT116 cells with IC 50 values ranging from 47.8 μg/mL to 232.0 μg/mL [10]. activity of methanol extract from two other nostocacean strains (Nostoc linckia and Anabaena oryzae) against HeLa cells with IC 50. values ranging from 151.4 μg/mL to 168.4 μg/mL [16].

Synthesis and cytotoxic activity of some 2-(2,3-dioxo-2,3-dihydro-1H -indol-1-yl)acetamide derivatives

tailieu.vn

The synthesized derivatives were screened for their cytotoxic activity against some tumor cell lines (MCF7, A549, HeLa) and one nontumor cell line (HEK293) by real-time cell assay. Cytotoxic activities of the title compounds.. >100. gt;100.

Green biosynthesis, characterization, and cytotoxic effect of magnetic iron nanoparticles using Brassica Oleracea var capitata sub var rubra (red cabbage) aqueous peel extract

tailieu.vn

Characterization, antioxidant, antimicrobial and cytotoxic activities of green synthesized silver and iron nanoparticles using alcoholic Blumea eriantha DC plant extract. British journal of cancer 2004. Ethnomedicinal plant-extract-assisted green synthesis of iron nanoparticles using Allium saralicum extract, and their antioxidant, cytotoxicity, antibacterial, antifungal and cutaneous wound-healing activities.

Synthesis and in vitro cytotoxic activity of novel pyrazolo[1,5-a]pyrimidines and related Schiff bases

tailieu.vn

MCF7 and liver HepG2 cancer cell lines,. 13 We report herein the synthesis of a new series of pyrazolo[1,5-a]pyrimidine derivatives and Schiff bases based on 5-aminopyrazole derivatives, and also investigation of the cytotoxic activities of the synthesized compounds against four human tumor cell lines (HCT116 “colon”, A549 “lung”, HepG2 “liver”, and MCF-7 “breast” cancers)..

Two new coordination polymers containing dicyanidoargentate(I) and dicyanidoaurate(I): synthesis and characterization, and a detailed in vitro investigation of their anticancer activities on some cancer cell lines

tailieu.vn

Cytotoxic activity of C1 , C2 , [Ag(CN) 2. on HT-29, HeLa, and C6 cells The in vitro cytotoxic activities of C1 , C2 , [Ag(CN) 2. Results of the LDH assay are expressed in terms of % cytotoxicity values and presented in Figure 2. Each coordination polymer exhibited the same cytotoxic activity as 5FU at IC50 concentration against any of the four cell lines.

A novel 1,4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells

tailieu.vn

As a result, the compound exhibits cytotoxic activities against both cell lines in a dose-dependent manner. In addition, mitochondria-mediated apoptotic cell death was detected in triple-negative MDA-MB-231 cells, indicating the potential importance of the compound.. The synthesis and characterization methods of the compound were published by Deniz et al. Cytotoxic activities of the compound were examined using the SRB cell viability assay.

Design, synthesis, and antitumor evaluation of novel methylene moiety-tethered tetrahydroquinoline derivatives

tailieu.vn

The cytotoxic activities of compounds 9a, 9b, and 11a were tested in a concentration-dependent (50–300 µM) and time-dependent (24–72 h) manner and expressed as IC 50. The results showed that compound 9a has the lowest IC 50 values for all cell lines, ranging from 111 ±1.1 µM to 128 ±1.3 µM (Table 1), when compared to 9b and 11a after 72 h. The IC 50 values did not vary significantly depending on cell line for compound 9a.

Synthesis of hydroxy benzoin/benzil analogs and investigation of their antioxidant, antimicrobial, enzyme inhibition, and cytotoxic activities

tailieu.vn

Antioxidant activities of the synthetic compounds 1-25 were tested against iron (III. Ferric reducing antioxidant power (FRAP) assay: The method was carried out based on the determination of the iron ions reducing the samples’ power. As a standard, different concentrations of Trolox solution and 250 μg/mL) were used instead of the sample. At the end of the incubation, the samples’. 1 > gt;1000 58.16. gt;1000 > .

Investigation of Olea ferruginea Roylebark extracts for potential in vitro antidiabetic and anticancer effects

tailieu.vn

This study has focused on the antidiabetic and cytotoxic activities of Olea ferruginea R bark extracts.. The nonenzymatic glycosylation of hemoglobin assay was performed on all 5 Olea ferruginea R bark extracts. The highest percentage of inhibition of nonenzymatic glycosylation of the bark extracts was observed for chloroform (65. The antidiabetic potential of Olea ferruginea R bark extracts were further assessed by alpha-amylase inhibition assay..

New flavonoid glycosides conjugates: Synthesis, characterization, and evaluation of their cytotoxic activities

tailieu.vn

1 H NMR (300 MHz, DMSO- d 6 ) (δ , ppm): 7.58 (dd, J 1 = 9, J 2 = 2.5 Hz, 1H), 7.67 (d, J = 8.4 Hz, 2H), 7.68 (d, J = 9 Hz, 1H), 7.93 (d, J = 2.5 Hz, 1H), 8.85 (d, J = 8.4 Hz, 2H). δ, ppm): 7.39 (d, J = 9 Hz,...

Bisbenzoxazole derivatives had an antiinflammatory effect on in vitro stimulated macrophages

tailieu.vn

Based on the Trypan blue assay our reagents lacked cytotoxic activities on the macrophages. Overall, bisbenzoxazole derivatives RHE 231 and RHE 238 have great potential as new drug candidates to modulate immune system cells without causing any cytotoxic effect. Currently, we are focusing on possible signaling pathways that are affected by our reagents..

Nickel(II)-PPh3 complexes with ONS and ONN chelating thiosemicarbazones: Synthesis and inhibition potential on influenza A viruses

tailieu.vn

Cytotoxic activities of the ligands and nickel(II) complexes were determined using the MTT assay in vitro against MDCK cells, and then all the compounds were tested on influenza virus replication by plaque assays.

Anticancer activities of stichoposide D isolated from the sea cucumber stichopus chloronotus on ntera-2 cancer stem cells

tailieu.vn

Herein, the cytotoxic potents, cell cycle arresting and apoptotic inductive activities of stichoposide D targeting pluripotent human embryonic carcinomas NTERA-2 cells will be presented.. carcinoma) cancer stem cell line were kind presents from Prof. Isolation of stichoposide D (SC9).

Summary of chemistry doctoral thesis: Study on chemical constituents and biological activities from the leaves of Excoecaria agallocha L. and Excoecaria cochinchinensis Lour.

tailieu.vn

Studied the cytotoxic, anti-inflammatory, and antimicrobial activities of the isolated compounds to find the bioactive compounds.. The main contents of the thesis. Isolation of compounds from the leaves of Excoecaria agallocha and E. Determination of chemical structures of the isolated compounds.. Evaluation of the cytotoxic, anti-inflammatory, and antimicrobial activities of the isolated metabolites to find out potential compounds.. cochinchinensis The leaves of E. The leaves of E.

Synthesis of novel 5-substituted phenyl-3-(p-isopropylphenyl)-1-phenylformazan and their biological activities

tailieu.vn

According to the cytotoxic activity results against C6 cells, 3a–3g are less toxic at the investigated highest dose than 5-FU. 3a–g exhibited both high antiproliferative activities and noncytotoxicity. Formazans 3a–g were prepared following the literature procedures.

Flavonoids and their cytotoxic activity from Tithonia diversifolia

tailieu.vn

FLAVONOIDS AND THEIR CYTOTOXIC ACTIVITY FROM TITHONIA DIVERSIFOLIA. Three flavones (1-3) were isolated from the aerial part of Tithonia diversifolia (Hemsl.) A. The compounds 1-3 showed cytotoxic activity against four human cancer (KB, Hep, Lu1 and MCF7) cell lines with IC 50 values ranging from g/mL to g/mL. Among them, compound 3 has shown the most potent effect on Hep and KB cell lines with IC g/mL and g/mL, respectively.. Keywords: Tithonia diversifolia (Hemsl.)

In-vitro antibacterial, antioxidant and cytotoxic potential of gold nanoparticles synthesized using novel Elaeocarpus ganitrus seeds extract

tailieu.vn

The cytotoxic activity of the Au nanoparticles exhibited strong cytotoxicity and improved the anti- cancer activity against the PC-3 cancer cell line. Moreover, this work has established the relevance of novel biomaterial Elaeocarpus ganitrus seeds extract in nanotechnology, through the rapid and eco- friendly synthesis of Au NPs with potential antibacterial, antioxidant and anticancer activities..

Cytotoxic activity of new phenolics from Dianella ensifolia (L.) DC.

tailieu.vn

Three of them (1, 2, and 4) were newly identified compounds and one (3) was obtained for the first time as natural product.With the aim to search for the cytotoxic agents from this plant, the present investigation was designed to evaluated cytotoxic activity of a phenolics (1-4) against four human cancer cell lines Hep3B, Hela, A549, and MCF-7.

Biosynthesis of silver nanoparticles using Onosma sericeum Willd. and evaluation of their catalytic properties and antibacterial and cytotoxic activity

tailieu.vn

As can be seen from the results, particle size had a significant effect on the cytotoxic effects of silver nanoparticles, and the two most cytotoxic silver nanoparticles were below approximately 20 nm. The mechanism of cytotoxic action of silver nanoparticles on cells may involve the induction of oxidative stress by way of the formation of free radicals and the production of reactive oxygen species (ROS)..