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Genome-wide DNA methylation

Tìm thấy 19+ kết quả cho từ khóa "Genome-wide DNA methylation"

MRCNN: A deep learning model for regression of genome-wide DNA methylation

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MRCNN: a deep learning model for regression of genome-wide DNA methylation. Background: Determination of genome-wide DNA methylation is significant for both basic research and drug development. Results: In this paper, we propose a deep learning method for prediction of the genome-wide DNA methylation, in which the Methylation Regression is implemented by Convolutional Neural Networks (MRCNN).

MethGET: Web-based bioinformatics software for correlating genome-wide DNA methylation and gene expression

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Correlation analyses of genome-wide DNA methylation and gene expression (correlation). To display the correlation between genome-wide DNA methylation and gene expression, MethGET generates scat- terplots and 2D kernel density plots. 2b that genes with lower expression are enriched in both high and low DNA methylation levels..

Cadmium-induced genome-wide DNA methylation changes in growth and oxidative metabolism in Drosophila melanogaster

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Cadmium-induced genome-wide DNA methylation changes in growth and oxidative metabolism in Drosophila melanogaster. DNA methylation is an important mechanism for the regulation of gene expression.. In this study we examined the effects of Cd exposure on global DNA methylation in a living organism by whole-genome bisulfite sequencing (WGBS) using Drosophila melanogaster as model..

Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs

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DNA methylation dynamics in muscle development and disease. Genome-wide DNA methylation changes with age in disease-free human skeletal muscle. Genome-wide DNA methylation changes in skeletal muscle between young and middle-aged pigs. Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation.

Genome-wide methylation and transcriptome of blood neutrophils reveal the roles of DNA methylation in affecting transcription of protein-coding genes and miRNAs in E. coli-infected mastitis cows

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DNA methylation is involved in the occurrence and development of bovine mastitis [8–. The present study aimed to analyze the genome-wide DNA methylation patterns of blood neutrophils in healthy and E. The average SCC in the milk of MC group was mL, which was significantly higher than HC group mL (P <. In the healthy group, the presence of bacteria growth in the culture plate was not observed. Genome-wide DNA methylation patterns of bovine blood neutrophils.

Genome-wide DNA methylation analysis revealed stable DNA methylation status during decidualization in human endometrial stromal cells

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Genome-wide DNA methylation analysis revealed stable DNA methylation status during decidualization in human. Here, we examined the genome-wide DNA methylation profiles in ESCs during decidualization and their associations with the changes of gene expressions and histone modifications.. The genome-wide DNA methylation profiles were compared between the non-decidualized ESCs and the decidualized ESCs. Of 482,005 CpGs, only 23 CpGs (0.0048%) showed different DNA methylation statuses.

Genome-wide DNA methylation analysis of Metarhizium anisopliae during tick mimicked infection condition

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Genome-wide DNA methylation analysis of Metarhizium anisopliae during tick. Among the different epigenetic modifications, DNA methylation of cytosine bases is an important mechanism to control gene expression in several organisms.

DNA methylation in infants with low and high body fatness

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In conclusion, this study reports no difference in genome-wide DNA methylation between 1-week-old in- fants with low and high body fatness.

Dynamic DNA methylation of ovaries during pubertal transition in gilts

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Profiling the genome-wide DNA methylation pattern of porcine ovaries using reduced representation bisulfite sequencing. A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters

The effect of DNA methylation on bumblebee colony development

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Parent-of-origin effects on genome-wide DNA methylation in the cape honey bee (Apis mellifera capensis) may be confounded by allele-specific methylation. Allele-specific transcriptome and methylome analysis reveals stable inheritance and cis-regulation of DNA methylation in Nasonia. DNA methylation and sex allocation in the parasitoid wasp Nasonia vitripennis. Genome-wide disruption of DNA methylation by 5-aza-2 ’ deoxycytidine in the parasitoid wasp Nasonia vitripennis.

DNA methylation patterns in peripheral blood mononuclear cells from Holstein cattle with variable milk yield

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DNA methylation patterns in peripheral blood mononuclear cells from Holstein cattle with variable milk yield. Epigenetic modifications to the cattle genome are a plausible molecular mechanism to cause variation in milk yield and our objective was to describe genome-wide DNA methylation patterns in peripheral blood mononuclear cells (PBMC) from mature Holstein dairy cows with variable milk yield..

DNA methylation patterns vary in boar sperm cells with different levels of DNA fragmentation

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Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling. Assembly of the pig genome (11.1). methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

DNA methylation of alu repeats in complicated urinary tract infection in children

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Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells. Global DNA methylation in neonatal sepsis. Impact of aging on DNA methylation. Alu element mutation spectra: molecular clocks and the effect of DNA methylation. Epigenomic analysis of Alu repeats in human ependymomas. Prediction of genome-wide DNA methylation in repetitive elements.. DNA Methylation of Alu Repeats in Complicated Urinary Tract Infection in Children.

A high-fat diet alters genome-wide DNA methylation and gene expression in SM/J mice

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This illustrates a common finding in obesity epigenetics studies: while there are methylation differences associ- ated with obesity, many changes in DNA methylation do not cause detectable changes in the expression of nearby genes. commonly studied overall but that our lab group has extensively characterized in the context of quantitative genetics, gene expression, and its obesogenic response to dietary fat [29 – 31]..

LPS-treatment of bovine endometrial epithelial cells causes differential DNA methylation of genes associated with inflammation and endometrial function

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The influence of experimentally induced endometritis on the PPAR expression profile in the bovine endometrium. methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

Continuous salt stress-induced long noncoding RNAs and DNA methylation patterns in soybean roots

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SoyTEdb: a comprehensive database of transposable elements in the soybean genome.. Liu Y, Liu J, Shen Y, Du J, Zhang J, Xing S, et al. Kapusta A, Kronenberg Z, Lynch VJ, Zhuo X, Ramsay LA, Bourque G, et al.. Positionally-conserved but sequence-diverged: identification of long non-coding RNAs in the Brassicaceae and Cleomaceae. Kong L, Xia G, Yuan J, Xie C, Wang M, Li W, et al. Genome-wide DNA methylation analysis in response to salinity in the model plant caliph medic (Medicago truncatula).

Distinctions between sex and time in patterns of DNA methylation across puberty

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Epigenetics and sex differences in the brain: a genome-wide comparison of histone-3 lysine-4 trimethylation (H3K4me3) in male and female mice. Genetic and epigenetic factors underlying sex differences in the regulation of gene expression in the brain. et al. The evolution of sex differences in disease. Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation. Sex differences in DNA methylation of the cord blood are related to sex-bias psychiatric diseases.

Epigenetic analysis of high and low motile sperm populations reveals methylation variation in satellite regions within the pericentromeric position and in genes functionally related to sperm DNA organization and maintenance in Bos taurus

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DNA methylation in early development. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. DNA methylation in mouse gametogenesis. Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells. A unique regulatory phase of DNA methylation in the early mammalian embryo.

Whole-genome bisulfite sequencing of goat skins identifies signatures associated with hair cycling

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Sequencing and automated whole-genome optical mapping of the genome of a domestic goat (Capra hircus). Genome-wide analysis of DNA methylation in bovine placentas. Zhang Y, Li F, Feng X, Yang H, Zhu A, Pang J, et al. Genome-wide analysis of DNA methylation profiles on sheep ovaries associated with prolificacy using whole-genome bisulfite sequencing. Jin L, Jiang Z, Xia Y, Lou P, Chen L, Wang H, et al. Genome-wide DNA methylation changes in skeletal muscle between young and middle-aged pigs.

Analysis of DNA methylation profiles during sheep skeletal muscle development using whole-genome bisulfite sequencing

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Genome-wide DNA methylation profiling. Global DNA methylation analysis of the LD muscle was performed by WGBS with 30× genome coverage and >. The CG methylation levels were high with wide sections in the violin graph (Fig. 3a), but CHG and CHH methylation levels were low with nar- row sections in the violin graph (Fig.