Tìm thấy 20+ kết quả cho từ khóa "DNA methylation"
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Identification of disease-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease. DNA methylation dynamics during the mammalian life cycle. CpG-rich islands and the function of DNA methylation. Tissue specific DNA methylation of CpG islands in normal human adult. DNA methylation of colon mucosa in ulcerative colitis patients: correlation with inflammatory status. Prognostic DNA methylation biomarkers in ovarian cancer.
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Parent-of-origin effects on genome-wide DNA methylation in the cape honey bee (Apis mellifera capensis) may be confounded by allele-specific methylation. Allele-specific transcriptome and methylome analysis reveals stable inheritance and cis-regulation of DNA methylation in Nasonia. DNA methylation and sex allocation in the parasitoid wasp Nasonia vitripennis. Genome-wide disruption of DNA methylation by 5-aza-2 ’ deoxycytidine in the parasitoid wasp Nasonia vitripennis.
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Dynamic DNA methylation of ovaries during pubertal transition in gilts. Previous studies have suggested that the disrupted DNA methylation results in the delayed puberty. In this study, using gilts as a pubertal model, the genome-wide DNA methylation were profiled to explore their dynamics during pubertal transition across Pre-, In- and Post-puberty..
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Estimating the multiple testing correction significance threshold for sub-samples of EPIC array DNA methylation sites. Summary of results from tests of assumptions of linear re- gression separated by mean DNA methylation level. The number and percentage of DNA methylation sites significant for each test (P <. split by mean DNA methylation level. split by DNA methylation level standard deviation.
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In this study, as to Bombyx mori, it exhibits low levels of DNA methylation with about 0.185% and CG methylation is substantially enriched in gene bodies.. The function of DNA methylation on gene expression is well established, but the underlying mechanisms of this function are poorly understood. Color scale from green to blue represents DNA methylation level.
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Only one DNA methylation feature that shared the most similar methylation pattern with the CpG locus to be predicted was applied in the model.
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Notes on the role of dynamic DNA methylation in mammalian development. Plant genomic DNA methylation in response to stresses:. DNA methylation in cancer: too much, but also too little.. Dynamic DNA methylation: in the right place at the right time. DNA methylation analysis: choosing the right method. COHCAP: an integrative genomic pipeline for single- nucleotide resolution DNA methylation analysis. PiiL: visualization of DNA methylation and gene expression data in gene pathways.
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Predicting DNA methylation level across human tissues. DNA methylation and human disease. DNA methylation landscapes: provocative insights from epigenomics. Principles and challenges of genome-wide DNA methylation analysis. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements. DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning..
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Finally, hierarch- ical clustering analysis of the DNA methylation data identified two tumor subgroups, one of which showed increased DNA methylation.. The pattern of DNA methylation in some certain types of cancers has been investigated including NSCLC [12]..
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Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets. Intergenerational genomic DNA methylation patterns in mouse hybrid strains. Gender-specific postnatal demethylation and establishment of epigenetic memory. methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles.
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Early-life stress reduces DNA methylation of the Pomc gene in male mice. Dynamic DNA methylation programs persistent adverse effects of early-life stress. Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice. DNA methylation and memory formation. DNA methylation in memory formation: emerging insights. Cortical DNA methylation maintains remote memory. DNA methylation changes in plasticity genes accompany the formation and maintenance of memory.
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Effect of low-dose cadmium exposure on DNA methylation in the endangered European eel.. Inducible protein traps with dominant phenotypes for functional analysis of the Drosophila genome. Investigating the role of DNA methylation as an epigenetic mechanism in the pacific oyster (Crassostrea gigas). DNA methylation in insects. Epigenetic regulation of motor neuron cell death through DNA methylation. The early-life social environment and DNA methylation.
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Aberrant sperm DNA methylation predicts male fertility status and embryo quality. DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos. Establishment and functions of DNA methylation in the germline. DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination. Developmental origins of transgenerational sperm DNA methylation epimutations following ancestral DDT exposure.
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Genome-wide DNA methylation analysis of Metarhizium anisopliae during tick. Among the different epigenetic modifications, DNA methylation of cytosine bases is an important mechanism to control gene expression in several organisms.
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Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study. In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver. Identification of DNA methylation changes in newborns related to maternal smoking during pregnancy. Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse:.
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Indeed, changes in DNA methylation were found as a common factor for aging in mammals with a striking tissue-specificity for age related DNA methylation changes [8, 9].
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Therefore, investigating and evaluating DNA methylation as a powerfully auxiliary biomarker for cancer in general and lung cancer, in particular, is urgently needed.. Preliminary research on qualitative DNA methylation of genes involved in breast, colorectal cancer has been previously described to Vietnamese patients.
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However, collectively, the level of the DNA methylation in the gene body slightly decreased in response to salinity treatment. In general, DNA methylation of the promoter regions often leads to reduced gene expression [17]. Moreover plants can regulate the methylation level through demethylases of the DEMETER family such as those found in Arabidopsis [28].
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We determined that overall DNA methylation levels of genome were decreased after E. We demonstrated that DNA methylation in promoter regions affected the differential expression of immune-related genes, and DNA methylation in the exon regions regulated the alternative splicing pattern of genes. coli mastitis infection and identified genes CITED2, SLC40A1, and LGR4 that regulate the differential expression of genes by DNA methylation in the E.
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Correlation between DNA methylation and gene expression. The transcriptome- wide association between gene expression and DNA methylation within promoter regions and gene bodies was examined.