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Immunohistochemical staining


Tìm thấy 20+ kết quả cho từ khóa "Immunohistochemical staining"

TFEB, SIRT1, CARM1, Beclin-1 expression and PITX2 methylation in breast cancer chemoresistance: A retrospective study

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E Image at 20x (and in the box at 40x) of SIRT1 immunohistochemical staining in a primary breast cancer specimen of a woman with recurrent breast cancer within 12 months of follow-up. immunohistochemical staining in a primary breast cancer specimen of a woman without tumor recurrence within 12 months of follow-up.

Chapter 095. Carcinoma of Unknown Primary (Part 3)

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However, these cancers rarely present as CUP, so the yield of these tests may be low. 95-1 delineates a simple algorithm for immunohistochemical staining in CUP cases. Table 95-2 lists additional tests that may be useful to further define the tumor lineage. With the use of immunohistochemical markers, electron microscopic analysis, which is time- consuming and expensive, is rarely needed.. Approach to cytokeratin (CK7 and CK20) markers used in CUP..

Clinicopathologic features of TDO2 overexpression in renal cell carcinoma

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Kaplan-Meier analysis of RCC patients with high and low TDO2 expression. c Validating TDO2 expression in 12 pairs of normal and tumor tissue samples by qRT- PCR. d Immunohistochemical staining of TDO2 in a RCC sample, original magnification × 40. (e) Survival analysis of RCC patients with high and low TDO2 expression by Kaplan-Meier method. Immunohistochemical staining also revealed higher cytoplasmic expression of TDO2 in the tumor area compared with adjacent normal kidney (Figs.

The role of FoxP3+ regulatory T cells and IDO+ immune and tumor cells in malignant melanoma – an immunohistochemical study

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The staining pattern of IDO+. tumor cells was also cytoplasmic. The coverage of IDO+. Correlations of FoxP3+ Treg and IDO+ stromal immune cell numbers with clinicopathological parameters. Correlations of IDO expression and intensity of melanoma cells with clinicopathological parameters. The presence of IDO+. 2 Representative immunohistochemical stainings of IDO. Immunohistochemical stainings of IDO in benign (a) and dysplastic nevi (b), in situ melanoma (c), superficial (Breslow ’ s depth <.

MARCH6 promotes hepatocellular carcinoma development through upregulation of ATF2

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Methods: Expression of MARCH6 in human HCC samples was checked by immunohistochemical staining assay.. Clinical relevance of MARCH6 and activating transcription factor 2 (ATF2) was analyzed from TCGA database. Over-expression of MARCH6 was associated with poor prognosis of HCC patients. Up-expression of MARCH6 promoted cell growth and migration of HCC cells. The expression of ATF2 was potentiated by MARCH6 over-.

Cancer cell line microarray as a novel screening method for identification of radioresistance biomarkers in head and neck squamous cell carcinoma

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B-C Loss of CIP2A immunohistochemical staining in shRNA-silenced cell line in comparison with the non-silenced cell line UT-SCC-14. D-F Loss of CIP2A immunohistochemical staining in both shRNA-silenced cell line versions of UT-SCC-24A. Table 3 Immunohistochemistry of UT-SCC-14 and UT-SCC-24A and corrresponding CIP2A-shRNA-silenced cell lines. Non-treated UT-SCC-14 2 mutated . CIP2A-shRNA-silenced UT-SCC-14 (plasmid 557) 1 mutated . Non-treated UT-SCC-24A 3 absent .

“New insights” in the diagnosis & management of hirschsprung disease

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DiagnosEc value of rectal sucEon biopsies using calreEnin immunohistochemical staining in Hirschsprung's disease. backbone, from Shi et al. Tran VQ, et al. Bruder, Histopathological Diagnosis and Differential Diagnosis of Hirschsprung’s Disease, in Hirschsprung's Disease and Allied Disorders, A.M. Guinard-Samuel, V., et al., Calre8nin immunohistochemistry: a simple and efficient tool to diagnose Hirschsprung disease.

Effects of aging on the histology and biochemistry of rat tendon healing

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Comparison of the expression levels of Col-1, Col-3, MMP-1 and TIMP-1 in young and aged rat tendons by immunohistochemical staining. Quantitative analysis of the immunohistochemical staining of Col-1, Col-3, MMP-1 and TIMP-1. The healing mechanism of tendon injuries in aged rats remains unknown. In histological results, we found that the organization of the repair tissue of the tendon callus was completely changed in aged tendons.

An exploration of immunohistochemistrybased prognostic markers in patients undergoing curative resections for colon cancer

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The aim was to investigate the prognostic value of immunohistochemical markers in patients with colon cancer.. Immunohistochemical staining with HLA‑G, PD‑L1, CDX2, CD3, and CD8 was performed on tissue samples with rep‑. The expression of CD3 and CD8 was reported as a merged score based on the expression of both markers in the invasive margin and the tumour centre. In multivariable regression analysis positive HLA‑G expression (HR CI was associated with higher recurrence rates, while a pre‑.

Effects of prebiotic galacto-oligosaccharide on postoperative cognitive dysfunction and neuroinflammation through targeting of the gut-brain axis

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Iba-1 expression in the CA1 area of the hippocampus Results from immunohistochemical staining indicated that the Iba-1 positive cell was significantly increased in the CA1 area of the hippocampi of rats in the Surgery group ( P <. B-GOS-fed rats show a reduced Iba-1 positive cell in the hippocampal CA1 area after surgery ( P <.

IFITM1, CD10, SMA, and h-caldesmon as a helpful combination in differential diagnosis between endometrial stromal tumor and cellular leiomyoma

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Table 1 Intensity of immunohistochemical staining of IFITM1, CD10, h-caldesmon and SMA in endometrial stromal tumor and cellular leiomyoma. Abbreviations: EST indicates Endometrial Stromal Tumor, CL indicates Cellular Leiomyoma. Considering the specificity of the tumor and the ten- dency of the paraffin tissue to flake off, two punctures were performed in different areas of each tumor wax block. One section was stained with H&E to evaluate the presence of the tumour by light microscopy..

Secretion of BMP-2 by tumorassociated macrophages (TAM) promotes microcalcifcations in breast cancer

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The aim of this study is to elucidate the role of secretion of BMP-2 by TAMs in promoting microcalcifica- tions of breast cancer through immunohistochemical staining and co-culturing of breast cancer cells with TAMs.. Methods: A total of 272 patients diagnosed with primary invasive breast cancer from January 2010 to January 2012 in the First Hospital of China Medical University were included in this study.

Chapter 087. Gastrointestinal Tract Cancer (Part 9)

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Testing tumor cells through molecular analysis of DNA or immunohistochemical staining of paraffin- fixed tissue for "microsatellite instability". (sequence changes reflecting defective mismatch repair) in patients under age 50 with colorectal cancer and a positive family history for colorectal or endometrial cancer may identify probands with HNPCC..

Identification of TRPV4 as a novel target in invasiveness of colorectal cancer

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A and B representative images and summary data of immunohistochemical staining of TRPV4 and ZEB1 in patients with or without lymph node metastasis (N0 n = 59, N1 – 2 n = 47) Scale bar:. C Pearson correction of TRPV4 expression with ZEB1 ( n = 106), data were analyzed using the Pearson correlation test. D Signaling connections involved in the TRPV4-modulated epithelial-mesenchymal transition (EMT) process in human colon cancer.

Cost-effectiveness analysis of first-line treatment with crizotinib in ROS1- rearranged advanced non-small cell lung cancer (NSCLC) in Canada

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A validation study for the use of ROS1 immunohistochemical staining in screening for ROS1 translocations in lung cancer. https://doi.org/10.1016/j.jtho . Wu Y-L, Yang JC-H, Kim D-W, Lu S, Zhou J, Seto T, et al. Phase II study of Crizotinib in east Asian patients with ROS1-positive advanced non – small-cell lung Cancer. https://doi.org/10.1200/. Mazières J, Rouvière D, Milia JD, Filleron T, Zalcman G, Biondani P, et al.. doi:https://doi.org/10.1200/JCO .

Circadian miR-449c-5p regulates uterine Ca2+ transport during eggshell calcification in chickens

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A Immunohistochemical staining with the ATP2B4 antibody visualized using chromogen diaminobenzene (brown staining) in the chicken uterus. 5 ATP2B4 regulated Ca 2+ transfer in the uterine tubular gland cells. 6 Clock-controlled miR-449c-5p regulates Ca 2+ transport by targeting ATP2B4 in chicken uterine tubular gland cells. A and B Fluorescence intensity was observed and analyzed after overexpression of miR-449c-5p.

Morphologic and molecular correlates of EZH2 as a predictor of platinum resistance in high-grade ovarian serous carcinoma

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EZH2 expression and clinicopathologic features in HGSOC EZH2 expression was evaluated in tumor epithelium of all subjects included in the study. immunohistochemical staining of EZH2 is shown in Fig. EZH2 expression was absent from normal stroma samples (n = 40) and was only quantified digitally..

The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas

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B Statistical results of the immunohistochemical staining. Survival analysis showed that the prognosis of the mice in the combined treatment group was significantly better (Fig. HOTAIR expression of gliomas, the expression of PPARΑ protein was increased, and the CD34 and Ki67 protein expression of the combined treatment group was lower than that of the other two groups. These results indicated that in an in vivo environment, reducing the expression of HOTAIR combined with treatment with.

Ung thư biểu mô tế bào thận có đột biến TFE3/Xp11.2 báo cáo một trường hợp ở trẻ em và đối chiếu y văn

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After tumor resection, histopathological examination, immunohistochemical staining was positive for TFE3, CD10, negative for CK7, diagnosis renal cell carcinoma associated with Xp11.2 translocation factor E3 gene fusion. Key word: Renal cell carcinoma, TFE3, Xp11.2 translocation.. Ung thư biểu mô tế bào thận có đột biến TFE3/Xp11.2 là một dưới nhóm hiếm gặp của.

Extracellular vesicles mediated proinflammatory macrophage phenotype induced by radiotherapy in cervical cancer

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These results indicate that there was no significant change in polarization of peripheral macrophages in cervical cancer patients after radiotherapy.. 1 Immunohistochemical staining for tumor-associated macrophages (TAM) in cervical cancer tissue. The biopsies of cervical cancer patients were collected before and after radiotherapy.