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Post-operative cognitive dysfunction


Tìm thấy 14+ kết quả cho từ khóa "Post-operative cognitive dysfunction"

Risk factors for early postoperative cognitive dysfunction after colorectal surgery

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Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators International Study of Post-Operative Cognitive Dysfunction. Recovery of postoperative cognitive function in elderly patients after a long duration of desflurane anesthesia: a pilot study. New insights into the pathophysiology of postoperative cognitive dysfunction.

Postoperative cognitive dysfunction after robot-assisted radical cystectomy (RARC) with cerebral oxygen monitoring an observational prospective cohort pilot study

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International Study of Post-Operative Cognitive Dysfunction. Influence of the postoperative inflammatory response on cognitive decline in elderly patients undergoing on-pump cardiac surgery: a controlled, prospective observational study. Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia aging study

Effects of prebiotic galacto-oligosaccharide on postoperative cognitive dysfunction and neuroinflammation through targeting of the gut-brain axis

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In summary, our data provides laboratory evidence for the beneficial role of the prebiotic B-GOS on surgery-induced neuroinflammation and cognitive dysfunction in early post- surgery through the gut-brain axis. More important, this study supports the potential for a new therapy for POCD in the field of nutritional neuropsychopharmacology.. POCD: postoperative cognitive dysfunction.

A high risk of sleep apnea is associated with less postoperative cognitive dysfunction after intravenous anesthesia: Results of an observational pilot study

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Remote ischemic preconditioning prevents deterioration of short-term postoperative cognitive function after cardiac surgery using cardiopulmonary bypass:. The hidden epidemic of cognitive dysfunction in the older surgical patient.

High-fat diet aggravates postoperative cognitive dysfunction in aged mice

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High-fat diet aggravates postoperative cognitive dysfunction in aged mice. Although Sirt1 and apoptosis are significant responders to HFD in the brain, little is known regarding the functional correlations between HFD and POCD.. The expression levels of Sirt1, Bcl-2, Bax and caspase-3 cleaved were detected by western blot.. Results: The MWM and western blotting results showed that the learning and memory abilities were decreased in the HFC group compared with the ALC group.

MiR-190a potentially ameliorates postoperative cognitive dysfunction by regulating Tiam1

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MiR-190a potentially ameliorates postoperative cognitive dysfunction by regulating Tiam1. The aim of current study was to screen the POCD-related miRNAs in the hippocampus tissues and. Methods: The miRNA microarray was used to find the abnormal expression of miRNAs in the hippocampus tissues from the POCD model mice to normal mice (Discovery cohort, 3 vs 3).

Anesthesiology and cognitive impairment: A narrative review of current clinical literature

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The International Study of Post-Operative Cognitive Dysfunction (ISPOCD1) from 1998 increased interest in the association between surgery and perioperative neurocognitive disorders in non-cardiac surgery. Furthermore, the mean age of the study population was 63.9 and 66.9 in the GA and spinal groups, respectively, and patients with pre-existing cognitive dysfunction were excluded from the study,.

IL-17A promotes the neuroinflammation and cognitive function in sevoflurane anesthetized aged rats via activation of NFκB signaling pathway

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Conclusion: Anti-IL-17A may alleviate neuroinflammation and oxidative stress via inhibiting NF- κ B pathway, thereby attenuating post-operative cognitive dysfunction (POCD) in aged rats anaesthetized with sevoflurane..

The influences of anesthesia methods on some complications after orthopedic surgery: A Bayesian network meta-analysis

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In addition, Ewan et al. have documented that general anesthesia increases the risk of post-operative cognitive dysfunction compared with other anesthesia methods [10]. Considering of these evidences, there is still no clear consensus in anesthesia during orthopedic surgery.. In the current study, a network meta-analysis was per- formed to comprehensively estimate the effects of differ- ent anesthesia manners, such as general anesthesia on the outcomes of orthopedic surgery.

The impact of inhalation anesthetics on early postoperative cognitive function and recovery characteristics in Down syndrome patients: A randomized, double – blind study

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The recovery of cognitive function after general anesthesia in elderly patients: a compari- son of desflurane and sevoflurane. Postoperative cognitive dysfunction in the elderly:. Preliminary evaluation of a scale to assess cognitive function in adults with Down’s syndrome: the Prudhoe cognitive function test. The Prudhoe cognitive function test, a scale to assess cognitive function in adults with Down’s syndrome: inter-rater and test-retest reliability.

The correlation of intraoperative hypotension and postoperative cognitive impairment: A meta-analysis of randomized controlled trials

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Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. Postoperative cognitive dysfunction is independent of type of surgery and anesthetic

Perioperative Dexmedetomidine for outpatient cataract surgery: A systematic review

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The effects of dexmedetomidine on post-operative cognitive dysfunction and. Confusion/delirium following cataract surgery: an incidence study of 1-year duration. Prevention of cognitive dysfunction after cataract surgery with intravenous Administration of Midazolam and Dexmedetomidine in elderly patients undergoing cataract surgery. Postoperative pain after cataract surgery. Preoperative factors associated with IOP reduction after cataract surgery

Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway

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Addition- ally, DEX has been shown to improve post-operative cognitive dysfunction in aging mice by inhibition of the hippocampal inflammatory response and reduction of neuronal apoptosis [16]. Taken together, these data sug- gest that DEX has anti-inflammatory properties in the central nervous system (CNS)..

Effects of dexamethasone on postoperative cognitive dysfunction and delirium in adults following general anaesthesia: A meta-analysis of randomised controlled trials

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However, dexamethasone did not reduce the incidence of POD in our meta-analysis. only included one study [23], in which the results of the first post-operative day exhibited a sig- nificant reduction of delirium incidence in the dexa- methasone group compared with the control group, but not in the second and third post-operative days.. Toner et al.

Influence of the postoperative inflammatory response on cognitive decline in elderly patients undergoing onpump cardiac surgery: A controlled, prospective observational study

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Relationship with post- operative cognitive dysfunction in elderly patients. C-reactive protein and inflammatory response associated to neurocognitive decline following cardiac surgery. Is there a relationship between cognitive dysfunction and systemic inflammatory response after cardiopulmonary bypass? Ann Thorac Surg.. Statement of consensus on assessment of neurobehavioral outcomes after cardiac surgery

Comparison of general anesthesia with endotracheal intubation, combined spinalepidural anesthesia, and general anesthesia with laryngeal mask airway and nerve block for intertrochanteric fracture surgeries in elderly patients: A retrospective cohort study

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Analysis of postoperative cognitive dysfunction and influencing factors of dexmedetomidine anesthesia in elderly patients with colorectal cancer. Li LQ, et al. Effects of different analgesia regimens on early post- operative cognitive dysfunction in elderly patients undergoing radical resection of cervical carcinoma. Ezhevskaya AA, et al. Wang Y, et al. The effects of postoperative pain and its management on postoperative cognitive dysfunction. Kraychete DC, et al. Gu H, et al.

Risk factors and predictive value of perioperative neurocognitive disorders in elderly patients with gastrointestinal tumors

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Long-term postoperative cognitive dysfunction in the elderly ISPOCD1. https://doi.org/10.1097/ALN.. https://doi.. org/10.1016/j.neubiorev

Effects of resveratrol pretreatment on endoplasmic reticulum stress and cognitive function after surgery in aged mice

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ERS could be involved in cognitive function. Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behavior by blocking ERS in the mouse hippocampus [46].. In summary, resveratrol pretreatment could activate Sirt1 expression and reduce postoperative ERS in aged mice.. ERS: Endoplasmic reticulum stress. POCD: Postoperative cognitive dysfunction. Postoperative cognitive dysfunction in geriatric patients.

Pre-operative biomarkers and imaging tests as predictors of post-operative delirium in non-cardiac surgical patients: A systematic review

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Cerebral blood flow MRI in the nondemented elderly is not predictive of post-operative delirium but is correlated with cognitive performance. Racine AM, Fong TG, Travison TG, Jones R, Gou Y, Vasunilashorn S, et al. Yen TE, Allen JC, Rivelli SK, Patterson SC, Metcalf MR, Flink BJ, et al. Association between serum IGF-I levels and postoperative delirium in elderly subjects undergoing elective knee arthroplasty. Bohner H, Hummel TC, Habel U, Miller C, Reinbott S, Yang Q, et al..