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Có 20+ tài liệu thuộc chủ đề "Oxidative stress"

Physiological and transcriptomic analyses reveal the roles of secondary metabolism in the adaptive responses of Stylosanthes to manganese toxicity

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Physiological and transcriptomic analyses reveal the roles of secondary metabolism in the adaptive responses of Stylosanthes to manganese toxicity. However, little is known about the adaptive responses of stylo to Mn toxicity. Thus, this study integrated both physiological and transcriptomic analyses of stylo subjected to Mn toxicity.. In contrast, the activities of enzymes, such as peroxidase (POD), phenylalanine ammonia-lyase (PAL)...

Genomic evidence of the illumination response mechanism and evolutionary history of magnetotactic bacteria within the Rhodospirillaceae family

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Genomic evidence of the illumination response mechanism and evolutionary history of magnetotactic bacteria within the Rhodospirillaceae family. Results: We utilized genomes of the well-sequenced genus Magnetospirillum, including the newly sequenced MTB strain Magnetospirillum sp. XM-1 to perform a comprehensive genomic comparison with phototrophic bacteria within the family Rhodospirillaceae regarding the illumination response mechanism. First, photoreceptor genes were identified in the...

Comparative transcriptomic analysis unveils interactions between the regulatory CarS protein and light response in Fusarium

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The genes of the carotenoid pathway and their regulation have been investigated in detail in Fusarium fujikuroi. oxysporum, deep-pigmented mutants affected in the gene carS, which encodes a protein of the RING-finger family, overproduce carotenoids irrespective of light. The number of the latter decreases drastically in a carS mutant (1.1% vs. Moreover, approximately 27% of the genes activated at least...

Global analysis of sRNA target genes in Mycoplasma hyopneumoniae

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Global analysis of sRNA target genes in Mycoplasma hyopneumoniae. We performed a global analysis of the sRNAs, sRNA target genes and regulatory elements previously identified in their genome and analyzed the expression of some sRNAs and their target genes by quantitative RT-PCR (qPCR) in three different culture conditions.. Results: Seven of the 145 sRNA target genes are organized as monocistronic...

Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion

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Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion. characteristic for the combination of oxidative stress plus iron deprivation. Our experimental data suggest that the physiological effects of combined stresses and the survival of the fungus highly depend on fragile balances between economization of iron and production of essential iron-containing proteins. fumigatus iron deprivation aggravates oxidative...

Transcriptome profiles associated with selenium-deficiency-dependent oxidative stress identify potential diagnostic and therapeutic targets in liver cancer cells

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Cancer is one of the major public health problems worldwide, being the second most deadly disease, according to the World Health Organization, and nearly 30 million new cases are estimated to occur globally by 2040 (Siegel et al., 2020). Hepatocellular carcinoma (HCC) is the fourth most fatal and the fifth most frequent cancer worldwide (Bray et al., 2018). due to...

The endogenous L-cysteine desulfhydrase and hydrogen sulfide participate in supplemented phosphorus-induced tolerance to salinity stress in maize (Zea mays) plants

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Salinity stress is a premier impediment for plant growth and development (Negrão et al., 2017). Additionally, salinity leads to oxidative stress in plants because of overaccumulation of reactive oxygen species (Verma et al., 2019).. Phosphorus deficiency leads to reduced biomass and grain yield of plants (Vandamme et al., 2016). Salinity stress causes P deficiency in plants. hence, application of supplementary...

Regulation of antioxidant activity in maize (Zea mays L.) by exogenous application of sulfur under saline conditions

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Mukwevho et al., 2014. Hence, appropriate concentrations of sulfur are needed for proper activity of various antioxidants involved in scavenging the reactive oxygen species produced under salt-stress conditions.. Application of sulfur is very helpful for improving maize productivity, because maize responds quickly to sulfur fertilization (Riffat and Ahmad, 2018b). Regulation of antioxidant activity in maize (Zea mays L.) by exogenous...

Ethanol extract of basella alba linn modulates acrylamide induced oxidative stress in wistar rats

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Close to two decades now, acrylamide was reported among food carcinogens as a result of its discovery in some high- temperature processed carbohydrate-rich foods (Tareke et al., 2002. This exposure to acrylamide through different routes creates its bioavailability in the body system, got metabolized and converted to excretable macapturic acid metabolites which are excreted out of the body (Botcher et...

IL-17A promotes the neuroinflammation and cognitive function in sevoflurane anesthetized aged rats via activation of NFκB signaling pathway

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IL-17A promotes the neuroinflammation and cognitive function in sevoflurane. anesthetized aged rats via activation of NF- κ B signaling pathway. Background: To investigate the role of IL-17A in the neuroinflammation and cognitive function of aged rats anaesthetized with sevoflurane through NF- κ B pathway.. anti-IL-17A (injected with IL-17A antibody, inhale oxygen and sevoflurane), and Sevo + NC groups (injected with...

Can apneic oxygen insufflation become a novel lung protective ventilation strategy? A randomized, controlled, blinded, single center clinical trial

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Methods: Fifty-four adults (ASA II-III) undergoing esophagectomy with OLV were enrolled in the study. A bronchoalveolar lavage(BAL) was performed after OLV on the non-ventilated lung. Proinflammatory cytokine, oxidative stress markers(TNF- α , NF- κ B,sICAM-1,IL-6,IL-10,SOD,MDA) and SP-A, B, C were analyzed in serum and BALF as the primary endpoint.The clinical outcome determined by PPCs was assessed as the secondary endpoint.....

Risk factors for early postoperative cognitive dysfunction after colorectal surgery

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Risk factors for early postoperative cognitive dysfunction after colorectal surgery. Background: It has been reported that postoperative cognitive dysfunction (POCD) is correlated with the degeneration of the central nervous system, oxidative stress, inflammation, and endocrine and immune dysfunction. Increased age, predisposed comorbidity, long surgery time, and prolonged stay in the intensive care unit have been reported to be risk factors...

Effects and mechanism of dexmedetomidine on neuronal cell injury induced by hypoxia-ischemia

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dexmedetomidine on neuronal cell injury induced by hypoxia-ischemia. Background: The present study aims to investigate the protective effects of dexmedetomidine (DMED) on hypoxia ischemia injury induced by oxygen and glucose deprivation (OGD) in PC12 and primary neuronal cells.. Methods: PC12 cells exposed to OGD was used to establish ischemia model. The OGD-induced cell injury was evaluated by alterations of cell...

The effects of feeding obese rats with bee bread on leptin and ghrelin expression

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The effects of feeding obese rats with bee bread on leptin and ghrelin expression. Leptin and ghrelin are fasting and fullness hormones regulating the body weight by affecting the total calorie intake of the fasting-fullness mechanism (Cooper et al., 2010). They show opposite effects to each other in the regulation of energy balance (Yang et al., 2010), and they influence...

DNA damage, oxidative stress, decreased viability and motility in common carp (Cyprinuscarpio L.) spermatozoa induced by tryptophan, phenylalanine and cysteine amino acids during short-term storage

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doi:10.3906/zoo-1910-34. Gilany et al., 2015). In fish, FAA are released by epithelial cells of the reproductive tracts or originated from the degradation complex protein by proteases enzymes (Setchell et al., 1967. Lahnsteiner et al., 1994. Ciereszko et al., 1998).. Because of their availability in seminal plasma of fish (Ciereszko et al.,2000), exogenous FAAs have been widely used for short- and...

Determination of oxidative, genotoxic, and histopathologic effects of metal pollution on the fish fauna inhabiting Karasu River, Turkey

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Heavy metals constitute the most significant part of these substances (Akpor et al., 2014). Mutation, the formation of tumors and cellular deaths are the major abnormalities that the pollution causes on the fish (Viana et al., 2017). Fish are widely used in the evaluation of the aquatic ecosystem, as their biochemical and physiological responses to environmental changes are highly sensitive...