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Chủ đề : Reactive oxygen species


Có 19+ tài liệu thuộc chủ đề "Reactive oxygen species"

Sex differences in early transcriptomic responses to oxidative stress in the copepod Tigriopus californicus

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Sex differences in early transcriptomic responses to oxidative stress in the copepod Tigriopus californicus. Background: Patterns of gene expression can be dramatically different between males and females of the same species, in part due to genes on sex chromosomes. Here we test for sex differences in early transcriptomic response to oxidative stress in a species which lacks heteromorphic sex chromosomes,...

Transcriptomic profiling of adipose tissue inflammation, remodeling, and lipid metabolism in periparturient dairy cows (Bos taurus)

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Transcriptomic profiling of adipose tissue inflammation, remodeling, and lipid. Background: Periparturient cows release fatty acid reserves from adipose tissue (AT) through lipolysis in response to the negative energy balance induced by physiological changes related to parturition and the onset of lactation. The objective of this study was to determine the effects of the periparturient period on the transcriptomic profile of...

Genome-wide characterization and evolutionary analysis of heat shock transcription factors (HSFs) to reveal their potential role under abiotic stresses in radish (Raphanus sativus L.)

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transcription factors (HSFs) to reveal their potential role under abiotic stresses in radish ( Raphanus sativus L.). Results: In this study, 33 RsHSF genes were obtained from the radish genome, which were classified into three main groups based on HSF protein domain structure. Chromosomal localization analysis revealed that 28 of 33 RsHSF genes were located on nine chromosomes, and 10...

Gene regulation of Sclerotinia sclerotiorum during infection of Glycine max: On the road to pathogenesis

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In the case of carpogenic germination, apothecia in the soil release millions of airborne ascospores which initially colonize the petals of soybean blossoms, before travelling through green tissue to the main stem of the plant. This journey through distinct regions of the host is important to note as the metabolic, virulence, and defense requirements of S. 2019 Open Access This...

Overexpression of herbaceous peony HSP70 confers high temperature tolerance

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HSP70 confers high temperature tolerance. However, their functions in herbaceous peony ( Paeonia lactiflora Pall.) under high temperature stress are poorly characterized.. The encoded protein with a molecular weight of 71 kDa was localized in the cytoplasm of the cell. lactiflora and increased with the treatment of high temperature stress. The constitutive overexpression of PlHSP70 in Arabidopsis thaliana obviously conferred...

Iron-dependent essential genes in Salmonella Typhimurium

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Iron-dependent essential genes in Salmonella Typhimurium. Typhimurium with insertions in essential genes escaped immediate killing or growth inhibition under iron-restricted conditions for approximately one-third of all previously known essential genes. Based on this result, we classified all essential genes into two categories, iron-dependent essential genes, for which the insertion mutants can grow slowly if iron is restricted, and iron-independent essential...

NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma

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NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma. Background: Increased expression of the transcription factor Forkhead box M1 (FOXM1) has been reported to play an important role in the progression and development of multiple tumors, but the molecular mechanisms that regulate FOXM1 expression remain unknown, and the role of FOXM1 in aerobic glycolysis is still not clear.. Methods:...

Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin

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photodynamic therapy in cancer cell lines of different origin. Results: Here, we report that photodynamic treatment of tumor cell lines of different origin in combination with Alectinib increased protoporphyrin-IX specific fluorescence and concomitantly cell death.. The aim of this study was to find out whether pre- treatment of tumor cells with Alectinib leads to an en- hanced concentration of PpIX...

Osteopontin isoform c promotes the survival of cisplatin-treated NSCLC cells involving NFATc2-mediated suppression on calcium-induced ROS levels

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Results: We found that the survival of NSCLC cells treated with cisplatin was increased by secretory OPNc in the condition medium, where reduction of apoptosis by OPNc was associated with the activation of cellular calcium signals and subsequent nuclear translocation of NFATc2.. The images or other third party material in this article are included in the article's Creative Commons licence,...

Estimation of genomic instability and DNA methylation due to aluminum (Al) stress in wheat (Triticum aestivum L.) using iPBS and CRED-iPBS analyses

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Estimation of genomic instability and DNA methylation due to aluminum (Al) stress in wheat (Triticum aestivum L.) using iPBS and CRED-iPBS analyses. Aluminum (Al) toxicity affects 15% of soils on earth (Bot et al., 2000) and is a primary stress factor in acidic arable land (Kochian, 1995). Al binds to the root cell walls, and is thought to prevent the...

Plant response to salinity: An analysis of ROS formation, signaling, and antioxidant defense

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More than 20% of the arable land on our planet is challenged by soil salinity, mostly with high Na + levels, which are referred to as sodic soils (Qadir et al., 2014).. The antioxidant defense system in plants comprises enzymatic and nonenzymatic components that are responsible for the scavenging of reactive oxygen species (ROS) (Mittler et al., 2004). In particular,...

The endogenous L-cysteine desulfhydrase and hydrogen sulfide participate in supplemented phosphorus-induced tolerance to salinity stress in maize (Zea mays) plants

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Salinity stress is a premier impediment for plant growth and development (Negrão et al., 2017). Additionally, salinity leads to oxidative stress in plants because of overaccumulation of reactive oxygen species (Verma et al., 2019).. Phosphorus deficiency leads to reduced biomass and grain yield of plants (Vandamme et al., 2016). Salinity stress causes P deficiency in plants. hence, application of supplementary...

Regulation of antioxidant activity in maize (Zea mays L.) by exogenous application of sulfur under saline conditions

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Mukwevho et al., 2014. Hence, appropriate concentrations of sulfur are needed for proper activity of various antioxidants involved in scavenging the reactive oxygen species produced under salt-stress conditions.. Application of sulfur is very helpful for improving maize productivity, because maize responds quickly to sulfur fertilization (Riffat and Ahmad, 2018b). Regulation of antioxidant activity in maize (Zea mays L.) by exogenous...

Synthesis, spectroscopic studies, and antioxidant activities of novel thio/carbohydrazones and bis-isatin derivatives from terephthalaldehyde

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The in vitro antioxidant activity of all the compounds was determined by the 1,1-diphenyl-2-picryl hydrazyl (DPPH. Compound 2 showed the best antioxidant activity.. All the synthesized compounds were elucidated using IR, 1 H NMR, and 13 C NMR spectroscopy and elemental analysis. The in vitro antioxidant activity of all the compounds was measured by the 1,1-diphenyl-2-picryl hydrazyl (DPPH. Antioxidant activity....

Beneficiall effect of the european raspberry (rubus iadeus) extract on the activity and oxidative profile of bovine spermatozoa

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BENEFICIALL EFFECT OF THE EUROPEAN RASPBERRY (RUBUS IADEUS) EXTRACT ON THE ACTIVITY AND OXIDATIVE PROFILE OF BOVINE SPERMATOZOA. Secondary metabolites produced by the plant are characterized by a relatively strong biological activity (Bobinaité et al., 2012). Fruits, especially berries contain sources of natural antioxidants and are an excellent component of a healthy diet (Baby et al., 2017). Anthocyanins can protect...

Mesenchymal stromal cells attenuate sevoflurane-induced apoptosis in human neuroglioma H4 cells

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sevoflurane-induced apoptosis in human neuroglioma H4 cells. However, whether MSCs can protect from sevoflurane-induced neuronal apoptosis and the potential mechanisms are unclear.. Methods: A non-contact co-culture of MSCs with human neuroglioma H4 cells (H4 cells) was built. H4 cells were co-cultured with MSCs or without MSCs (control) for 24 h. The co-cultured H4 cells were exposed to 4% sevoflurane for...

Deferoxamine preconditioning ameliorates mechanical ventilation-induced lung injury in rat model via ROS in alveolar macrophages: A randomized controlled study

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Deferoxamine preconditioning ameliorates mechanical ventilation-induced lung injury in rat model via ROS in alveolar. however, ventilatior-induced lung injury (VILI) has also been widely recognized in clinical practice, including in the healthy lung. The current study aimed to examine the effects of iron chelator preconditioning on the mitochondrial reactive oxygen species (ROS) in alveolar macrophages and pathological lung injury in VILI.....