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Virulence genes


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Genomic and ecological attributes of marine bacteriophages encoding bacterial virulence genes

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marine bacteriophages encoding bacterial virulence genes. The acquisition of phage- encoded virulence genes is a major mechanism for the rise of bacterial pathogens. In coral reefs, high bacterial density and lysogeny has been proposed to exacerbate reef decline through the transfer of phage-encoded virulence genes..

Sequencing of five poultry strains elucidates phylogenetic relationships and divergence in virulence genes in Morganella morganii

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Novel virulence genes were defined as those specific to cluster M2: a total of 39 novel virulence genes were found in this way (Table 5). This resulted in a final set of 26 novel virulence genes.. To find evidence for horizontal gene transfer the novel virulence genes were BLASTed against the whole bacterial protein database. 4 Comparison of known virulence genes in the five sequenced poultry strains using the KT strain as reference.

Comparative genomics and association analysis identifies virulence genes of Cercospora sojina in soybean

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We examined genes with significant differences in the number of NSY SNPS between low-virulence and high- virulence samples, as these genes were most likely re- lated to virulence. First, the virulence values of the 32 isolates were sorted from high to low. 3 Phylogenic tree of the 30 C. The values in parentheses are the virulence values of each of the isolates. The number on each branch indicates the reliability of the branch.

Comparative genomic analysis of Vibrios yields insights into genes associated with virulence towards C. gigas larvae

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Mutation of the toxR or mshA genes from Vibrio coralliilyticus strain OCN014 reduces infection of the coral Acropora cytherea: virulence genes in Vibrio coralliilyticus. The antimicrobial defense of the pacific oyster, crassostrea gigas.. Comparative Transcriptome analysis reveals molecular basis underlying fast growth of the selectively bred Pacific oyster, Crassostrea gigas. Transcriptome analysis of the pearl oyster ( Pinctada fucata ) hemocytes in response to Vibrio alginolyticus infection.

Genome-wide association studies reveal candidate genes associated to bacteraemia caused by ST93-IV CA-MRSA

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For example recent GWAS performed on livestock-associated CC398 MRSA, showed the clone frequently lost antimicrobial resistance genes and ac- quired human specific virulence genes in relation to the origin of the host [10].. Phylogenetic analysis of the genomes was performed by examining SNPs in the core genome and investigating the absence/presence of accessory genes.

Whole-genome analysis of probiotic product isolates reveals the presence of genes related to antimicrobial resistance, virulence factors, and toxic metabolites, posing potential health risks

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For VFs, 21, 19, and 8 virulence genes were identified in the genomes of S.. In the genome of S. a Species identification based on whole genome average nucleotide identity (ANI). b Species identification based whole genome using rMLST. c Species identification based whole genome using TYGS. In the genome of E. 90%) were found in the genomes of nine isolates (Fig. 4), suggesting that IS6 and IS3 contribute in the transfer of these virulence factors. In the genome of L..

Analysis of oral microbiome from fossil human remains revealed the significant differences in virulence factors of modern and ancient Tannerella forsythia

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The next 13 rings moving towards the inner part of the figure display regions of sequence similarity detected by BLAST comparison between the DNA of the reference genome and the DNA of the 13 compared T. forsythia virulence are labeled in the plot. forsythia virulence genes, only bspA (encoding the bacterial surface-associated protein) was not conserved in the ancient and most contempor- ary genomes (Fig.

Benchmarking hybrid assembly approaches for genomic analyses of bacterial pathogens using Illumina and Oxford Nanopore sequencing

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Only one exception existed that the reference genome and hybrid assemblies of Pseudomonas aeruginosa with mediocre-quality long reads carried 241 virulence genes, whereas 184 virulence genes were identified in the hybrid assemblies of low-quality long reads.

Comparative genomic analysis of a Shiga toxin-producing Escherichia coli (STEC) O145:H25 associated with a severe pediatric case of hemolytic uremic syndrome in Davidson County, Tennessee, US

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Unique virulence genes among O145:H25 strains may lead to the development of genetic markers Table 4 Virulence genes in STEC O145:H25 strain EN1I-0044-2. O145:H25 O145:H28 O157. EN1I-0044-2 CFSAN004176 CFSAN004177 RM13514 RM13516 Sakai. STEC O145:H25 strain EN1I-0044-2 was used in this study. The isolate EN1I-0044-2 obtained from patient’s stool sample was positive for both eae and stx2 genes by PCR and reported as serotype O145:H25 [33]..

Exploring the success of Brazilian endemic clone Pseudomonas aeruginosa ST277 and its association with the CRISPR-Cas system type I-C

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Therefore, these genes are related to the P. aeruginosa species, and not exclusively to the ST277 (Fig. Mutations in the virulence genes were analyzed using the genes from P. In silico analysis identified intact type I-C CRISPR-Cas systems in 33 genomes from ST277 (70%) (Fig. No other type of CRISPR-Cas system was found among the ST277 strains.. When present, the type I-C CRISPR-Cas system was uni- formly localized on PAGI-34 in the ST277 genomes ana- lyzed here..

Chẩn đoán vi khuẩn tả ở người đến xét nghiệm tại bệnh viện Quân y 103 năm 2013 bằng kỹ thuật PCR

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Genesis of the novel epidemic Vibrio cholerae O139 strain: evidence for horizontal transfer of genes involved in polysaccharide synthesis. Comparison of Vibrio cholerae O139 with V. cholerae O1 classical and El Tor biotypes. Comparison of antibiogram, virulence genes, ribotypes and DNA fingerprints of Vibrio cholerae of matching serogroups isolated from hospitalised diarrhoea cases and from the environment during 1997–1998 in Calcutta, India.

Rust expression browser: An open source database for simultaneous analysis of host and pathogen gene expression profiles with expVIP

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We also demonstrated the utility of the browser through investigation of expression of putative Pst virulence genes over time and examined the host plants response to Pst infection.. 1 John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK Full list of author information is available at the end of the article.

Đặc Điểm Hình Ảnh Và Mức Độ Tổn Thương Phổi Trên Xquang Ngực Ở Bệnh Nhân COVID-19

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Helicobacter pylori virulence genes. World Journal of Gastroenterology TÀI LIỆU THAM KHẢO 7. Mechanisms of disease: Duodenal ulcer promoting gene of Helicobacter Helicobacter pylori virulence factors. Alam J, Sarkar A, Karmadar BC, et al. Maeda S, Yoshida H, Ikenoue T, et al. Structure virulence factor dupA of Helicobacter pylori as an of pathogenicity island in Japanese, Helicobacter important risk determinant for disease manifestion: pylori, isolates. World Journal of Gastroenterology .

Đặc Điểm Hình Ảnh Và Mức Độ Tổn Thương Phổi Trên Xquang Ngực Ở Bệnh Nhân COVID-19

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Helicobacter pylori virulence genes. World Journal of Gastroenterology TÀI LIỆU THAM KHẢO 7. Mechanisms of disease: Duodenal ulcer promoting gene of Helicobacter Helicobacter pylori virulence factors. Alam J, Sarkar A, Karmadar BC, et al. Maeda S, Yoshida H, Ikenoue T, et al. Structure virulence factor dupA of Helicobacter pylori as an of pathogenicity island in Japanese, Helicobacter important risk determinant for disease manifestion: pylori, isolates. World Journal of Gastroenterology .

Genetic boundaries delineate the potential human pathogen Salmonella bongori into discrete lineages: Divergence and speciation

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We found that RKS3044 shared most of the virulence genes with the previously sequenced S. bongori strains and also lacked SPI-2, but on the other hand contained a novel T6SS (T6SS novel ) encoded in a new SPI (SPI- RKS3044) identified in this study. RKS3044 and conducted comparisons with the other sequenced S.

Genomic analyses of Burkholderia cenocepacia reveal multiple species with differential host-adaptation to plants and humans

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The conservation of en- vironment and plant adaptive traits and the absence of key virulence genes in strains of the third identity cluster and more distant outgroup species, indicate that B. (69.9 and 49.7% of the aver- age amount of genes across strains respectively), con- firming that B. cenocepacia was a derivative of the B. Interestingly, the Latin meaning of the same prefix is “to dine”.

Label free proteomics and systematic analysis of secretome reveals effector candidates regulated by SGE1 and FTF1 in the plant pathogen Fusarium oxysporum f. sp. cubense tropical race 4

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The Wor1-like protein Fgp1 regulates pathogenicity, toxin synthesis and reproduction in the phytopathogenic fungus Fusarium graminearum. the expression of the gene coding for the transcription factor FTF1 correlates with virulence. Diversifying selection in the wheat stem rust fungus acts predominantly on pathogen-associated gene families and reveals candidate effectors. Mites in the promoters of effector genes allow prediction of novel virulence genes in Fusarium oxysporum.

Historical genomics reveals the evolutionary mechanisms behind multiple outbreaks of the host-specific coffee wilt pathogen Fusarium xylarioides

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MITEs in the promoters of effector genes allow prediction of novel virulence genes in Fusarium oxysporum,. https://doi.org/10.. https://doi.org/10.1046/j.1365-313X x..

CAPRIB: A user-friendly tool to study amino acid changes and selection for the exploration of intra-genus evolution

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In the Mycobacterium tuberculosis complex (MTBC), at the spe- cies scale, thousands of single-nucleotide polymorphisms (SNPs) have been identified in numerous virulence genes [16]. In addition, multiple studies have also shown the im- portance of AA changes in the evolution of other molecu- lar determinants of the MTBC, such as in RskA [17] and PhoR [18], and during the emergence of antibiotic resistant mutants [19, 20].

Transcriptome-wide association study identifies putative elicitors/suppressor of Puccinia graminis f. sp. tritici that modulate barley rpg4-mediated stem rust resistance

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The use of the susceptible line Harrington without the R-genes was justified because in most patho- systems analyzed virulence effectors evolve in the patho- gen to target host virulence target genes/proteins to become adapted pathogens. The plant counteracts these interactions by evolving resistances to recognize these interactions that cause virulence thus the effectors become avirulence genes in the presence of the cognate resistance.