Có 20+ tài liệu thuộc chủ đề "bào chế thuốc"
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THUỐC UỐNG DÙNG CHO TRẺ EM. Việc nghiên cứu phát triển các công thức thuốc uống dùng cho trẻ em đang là vấn đề thách thức đối với các nhà nghiên cứu bào chế. Khó khăn lớn nhất đối với các dạng bào chế này là liều dùng tính theo cân nặng và phải hạn chế được mùi vị khó...
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Học viện Quân y đa bào chế thành công chế phẩm cao lỏng Kiện khớp tiêu thống (KKTT) có tác dụng tốt trên thực nghiệm và sử dụng lâm sàng nhưng gặp nhiều khó khăn trong vận chuyển bảo quàn và không tiện s ử dụng.. Mục tiêu: Nghiên cứu này được tiến hành nhằm hiện đại hoố bài thuốc,...
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NGHIÊN CỨU BÀO CHẾ TIỂU PHÂN NANO LORATADIN BẰNG PHƢƠNG PHÁP. KẾT TỦA TRONG DUNG MÔI. 2 KTTP Kích thƣớc tiểu phân. KTTP, PDI của nano loratadin khi bào chế với polymer khác nhau (n=3. KTTP và PDI của mẫu bào chế nano loratadin với nồng độ HPMC E6 khác nhau (n=3. KTTP, PDI, thế zeta của nano loratadin ở...
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N m linh chi có tên khoa h c là Ganoderma lucidum, màu nâu s m, mũ n m l n t 2-15cm. S dĩ, n m ấ ọ ẫ ấ ớ ừ ở ấ linh chi bán đ t nh t trong các lo i n m vì chúng là m t th o d ắ ấ ạ ấ...
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L i ti u th m th u ợ ể ẩ ấ. Đ ượ ọ c l c d dàng c u th n, ít b tái h p thu ng ễ ở ầ ậ ị ấ ở ố th n, không b phân h y b i chuy n hóa ậ ị ủ ở ể. Gi m tái h...
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-Công th c ứ : cho 100 viên:. Strychnin sulfat (dùng b t m 1% Strychnin sulfat) ộ ẹ 50 mg. Acid tartaric 0,25 g. Viên nén: d ượ c ph m r n, hình d ng xác đ nh, ch a l ẩ ắ ạ ị ứ ượ ng chính xác d ượ c ch t, ấ đ ượ...
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'Nature is not only odder than we think, but it is odder than we can think.'. It is really one of the most serious difficulties with which we have to contend. it is only its first stage.'. like all other sciences, it will get away by the scientific method.' 'Considered in itself, the experimental method is nothing but reasoning by...
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Complementary drugs are for use where, for any reason, drugs in the main list are unavailable, or there are exceptional medical circumstances, e.g.. Not every entry in the list is discussed in this book.. Drugs used to treat gout allopurinol. Disease-modifying agents used in rheumatic disorders azathioprine. Antiallergics and drugs used in anaphylaxis. Antidotes and other substances used in poisonings....
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Clinical pharmacology. Clinical pharmacology comprises all aspects of the scientific study of drugs in man. Successful use of the power conferred (by bio- technology in particular) requires understanding of the enormous complexity of the consequences of interference. All these issues are the concern of clinical pharmacologists and are the subject of this book.. The drug and information 'explosion' of the...
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Preclinical drug development. Discovery of new drugs in the laboratory is an exercise in prediction. Studies in animals and in humans. Failures of prediction occur and a drug may be abandoned at any stage,. New drug development is a colossally expensive and commercially driven activity.. The development of new medicines (drugs) is an exercise in prediction from laboratory studies in...
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The key to the ethics of such studies is informed consent from patients, efficient scientific design and review by an independent research ethics committee.The key. interpretative factors in the analysis of trial results are calculations of confidence intervals and statistical significance.The potential clinical significance needs to be considered within the confines of controlled clinical trials.This is best expressed by stating...
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The quality aspects may also need to be revised as manufacturing practices change. Only governments can provide the assurance about all those aspects in the life of a medicine, (in so far as it can be provided).. safety, in relation to its use: evaluation at the point of marketing is provisional in the sense that it is followed in the...
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Any drug may have names in all three of the following classes:. Nonproprietary Names (rINN). In this book proprietary names are distinguished by an initial capital letter.. It is obviously unsuitable for prescribing.. Manufacture is con- fined to the owner of the trade mark or to others licensed by the owner. NONPROPRIETARY NAMES. Clarity: because it gives information of the...
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infusion it is important to know when steady state has been reached, for maintaining the same dosing schedule will then ensure a constant amount of drug in the body and the patient will experience neither acute toxicity nor decline of effect. The t1/2 provides the answer: with the passage of each t1/2 period of time, the plasma concentration rises by...
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Substances that have a molecular weight in excess of 50 000 are excluded from the glomerular filtrate while those of molecular weight less than 10 000 (which includes almost all drugs) 21 pass easily through the pores of the glomerular membrane.. Cells of the proximal renal tubule actively transfer strongly charged molecules from the plasma to the tubular fluid. The...
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A curious by-product of the modern 'drug and prescribing explosion' is the rise in the incidence of nonfatal deliberate self-harm. In over 90% of instances in the UK, poisoning is the means chosen, usually by medi- cines taken in overdose and these amount to at least 70 000 hospital admissions per annum in England and Wales (population 51 million). of...
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The presence of poppy heads in the kitchen middens of the Swiss Lake Dwellers shows how early in his history man discovered the techniques of self- transcendence through drugs. The drives that induce a person more or less mentally healthy to resort to drugs to obtain chemical vacations from intolerable selfhood will be briefly considered here, as well as some...
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The acute effect of alcohol is to block NMDA receptors for which the normal agonist is glutamate, the main excitatory transmitter in the brain. Chronic exposure increases the number of NMDA receptors and also 'L type' calcium channels, while the action of the (inhibitory) GABA neurotransmitter is reduced.. The malnutrition complicates the long-term effects of alcohol itself.. cancer of the...
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Drugs and the skin. This account is confined to therapy directed primarily at the skin.. Pharmacokinetics of the skin. Topical preparations:Vehicles for presenting drugs to the skin. The stratum corneum (superficial keratin layer) is both the principal barrier to penetration of drugs into the skin and a reservoir for drugs. a corticosteroid may be detectable even 4 weeks after a...
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Drugs provide a degree of stability and control in the lives of those suffering from schizophrenia, a chronic. Similarly, the impact of medication in alleviating the burden on individuals, their families and society of depression, which has a lifetime prevalence of up to I in 6 of the population, is substantial. Disorders that would formerly have been grouped under 'neuroses'...