Có 86+ tài liệu thuộc chủ đề "cơ chế thần kinh"
tailieu.vn Xem trực tuyến Tải xuống
Giniatullin R, Nistri A, Yakel JL (2005) Desensitization of nicotinic ACh receptors: shaping cholinergic signaling. Gotti C, Moretti M, Bohr I, Ziabreva I, Vailati S, Longhi R, Riganti L, Gaimarri A, McKeith IG, Perry RH, Aarsland D, Larsen JP, Sher E, Beattie R, Clementi F, Court JA (2006a) Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer’s disease, Parkinson’s disease...
tailieu.vn Xem trực tuyến Tải xuống
Abstract The lysosomal storage diseases (LSD) are a heterogeneous group of disorders, characterized by the progressive accumulation of various substrates in multiple cell types, as a consequence of defects in the degradation of by-products of cellular turnover. Although the causal gene defects and corresponding enzyme, cofactor, or transport deficiency have been delineated, there remains incomplete understanding of the downstream pathways...
tailieu.vn Xem trực tuyến Tải xuống
Lysosomal Storage Diseases 795 The imino sugar miglustat has been shown to lead to partial glycosphingolipid synthesis inhibition and modification of disease course in treated patients with Gaucher disease (Pastores and Barnett, 2003). In patients with Niemann–Pick type C, miglustat has been shown to improve saccadic eye movements and swallowing difficulties (Patterson et al., 2007). Unfortunately, the miglustat trials in...
tailieu.vn Xem trực tuyến Tải xuống
Mammalian brain cells have an intrinsically higher index of genetic output and complexity compared to gene transcription profiles in other cells and tissue cell systems (Lukiw et al., 2000. Colangelo et al., 2002. Lukiw et al., 2005;. Macdonald et al., 2007). Idbaih et al., 2007. Juric et al., 2007. Culicchia et al., 2008).. Nicholas et al., 2006. Kavsan et al.,...
tailieu.vn Xem trực tuyến Tải xuống
outside of the CNS (Zhang and Lippard, 2003). The development of advanced combinatorial therapies involving surgery, radiotherapy, antiangiogenics, MBADs, miRNA antisense strategies, and chemotherapeutics remain as attractive and evolving strategies in the future clinical management of glioma and GBM.. Glioma and glioblastoma multiforme constitute highly complex, progressive, and insidious neoplastic disorders of the human CNS. Glioma and GBM each exhibit...
tailieu.vn Xem trực tuyến Tải xuống
caspases, role in, 19–23. BBB, see Blood–brain barrier (BBB) B cell translocation gene-1 (BTG1), 371 BDC, see Brain differentiated cell (BDC) Beriberi, 105. Blood–brain barrier (BBB Bombesin-related peptides, 449. therapeutic approaches, 795 blood–brain barrier (BBB), 796 enzyme enhancement therapy, 797 enzyme replacement therapy, 796 gene therapy, 797