Có 20+ tài liệu thuộc chủ đề "Chronic obstructive pulmonary disease"
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PHÂN LOẠI GIAI ĐOẠN BỆNH PHÔI TẮC NGHẼN MẠN TÍNH THEO GOLD 2011 Ở BỆNH NHÂN ĐIỀU TRỊ NỘI TRÚ. Mục tiêu nghiên cồn: Mô tả đặc điểm lâm sàng, cận lâm sàng, chức năng Ihông khí và phân loại giai đoạn. giai đoạn BPTNMT theo GOLD 2011 với GOLD 2006.. Đỗi tuọng nghiên cứu: 112 bệnh nhân được chần...
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Pain in Veterans with COPD: relationship with physical activity and exercise capacity. Methods: This retrospective secondary analysis includes three cohorts of Veterans with COPD who participated in longitudinal studies evaluating PA and exercise capacity with objective measures of daily step counts and 6-min walk test (6MWT) distance, respectively. Pain was assessed using the bodily pain domain of the Veterans RAND-36....
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Handgrip strength during admission. Background: Low handgrip strength (HGS) is independently associated with a higher exacerbation risk in stable chronic obstructive pulmonary disease (COPD). The primary endpoint was exacerbations within 12 months after the index admission, which needed emergency room visits or hospital admission. HGSw group showed a signifi‑. cantly higher rate of emergency room visits within 6, 9, and...
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Methods: This retrospective matched cohort study selected patients from Optum’s de-identified Clinformatics Data Mart database who initiated maintenance treatment with UMEC/VI or TIO between and index date defined as the first dispensing). 1 medical claim for COPD pre-index or on the index date. severe COPD-related exacerbations on the index date. and no fills for both UMEC/VI and TIO on the...
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an observational study protocol for relationship between plasma metabolome and the efficacy of systemic glucocorticoid in acute exacerbation of chronic obstructive pulmonary disease. Background: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) significantly increases the mortality of patients with COPD. Guidelines have recommended systemic glucocorticoid as a regular treatment.. Recently, evidence has shown that systemic glucocorticoid cannot be a benefit...
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for predicting in-hospital mortality in patients with acute exacerbations of chronic obstructive pulmonary disease with hypercapnic respiratory failure. Background: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common presentation in emergency departments (ED) that can be fatal. This study aimed to develop a mortality risk assessment model for patients presenting to the ED with AECOPD and hypercapnic respiratory...
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1 impairment and neutrophil-skewed systemic inflammation are associated with comorbidities in COPD. We previously reported that reduced SUV39H1 expression contributed to abnormal inflammation in COPD. Here, we aimed to determine whether impaired SUV39H1 expression in COPD patients associated with neutro‑. Methods: A total of 213 COPD patients and 13 healthy controls were recruited from the Shuang Ho Hospital, Taipei Medical...
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A weighted COPD PPI network was constructed using expression information and then COPD candidate genes were prioritized based on their corresponding disease risk scores in descending order.. Results: Further analysis demonstrated that the PEP method was robust in prioritizing disease candidate genes, and superior to other existing prioritization methods exploiting either topological or functional information. Top-ranked COPD candidate genes and...
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Opioids in patients with COPD and refractory dyspnea: literature review and design. Background: Refractory dyspnea or breathlessness is a common symptom in patients with advanced chronic obstructive pulmonary disease (COPD), with a high negative impact on quality of life (QoL). Low dosed opioids have been investigated for refractory dyspnea in COPD and other life‑limiting conditions, and some positive effects were...
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Respiratory nurses are part of a multi-disciplinary team managing COPD patients, however, the nursing perspective on the term ‘exacerbation’ is unknown.. The aim was to understand the nurse perspective on ‘exacerbation’. Alternative terms used in the UK were compared versus the term ’exacerbation’.. There was no consensus on preference or meaning for the term ‘exacerbation’ between nurses. Less than 5%...
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Ultrasound assessment of the rectus femoris in patients with chronic obstructive pulmonary disease predicts poor exercise tolerance:. The thickness (RF thick ) and cross-sectional area (RF csa ) of the rectus femoris were measured using ultrasound. Standardized RF thick (STD- RF thick ) and Standardized RF csa (STD-RFcsa) were obtained via standardization of RF thick and RF csa by patients’...
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Lysophosphatidic acid species are associated with exacerbation in chronic obstructive. pulmonary disease. The aim of the study was to investigate the utility of serum LPA species (LPA as biomarkers of COPD exacerbation.. Patients and methods: LPA species were measured in the baseline placebo sera of a COPD randomized controlled trial. Tertile levels of each LPA were used to assign patients...
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Optimizing inhalation therapy in the aspect of peak inhalation flow rate in patients. with chronic obstructive pulmonary disease or asthma. delivering devices for patients with chronic airway diseases. Appropriate peak inhalation flow rate (PIFR) and inhaler technique is essential for effective therapy. We aimed at optimizing inhalation therapy through the analysis of PIFRs in patients with chronic obstructive pulmonary disease...
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Multi-channel lung sounds intelligent. diagnosis of chronic obstructive pulmonary disease. Results: This study established an effective model for the preliminary diagnosis of COPD severity using lung sounds with few channels. Firstly, the time-frequency-energy features of 12 channels lung sounds were extracted by Hilbert–. Finally, the feature sets were input into a support vector machine to diagnose COPD severity, and the...
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Prediction of readmission in patients. Variables with statistical significance were included in the logistic model and variables with P <. 0.1 were included in the XGBoost model, and receiver operator characteristic (ROC) curves were plotted.. 0.001) were associated with the risk of readmission. The AUC value of the logistic model was CI in the training set and CI in the...
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Prediction of gold stage in patients. tive of this study was to develop a prediction model to identify the GOLD stage in the hospitalized exacerbation of chronic obstructive pulmonary disease (ECOPD) patients.. A support vector regression (SVR) based GOLD stage prediction model was built using the training data set (75. The SVR model managed to predict the GOLD stage with...
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Determination of oxygen saturation. compared to a prescribed target range using continuous pulse oximetry in acutely unwell medical patients. Background: Both inadequate and excessive administration of oxygen to acutely unwell patients results in risk of harm. Guidelines recommend titration of oxygen to achieve a target oxygen saturation (SpO 2 ) range. Methods: In this two-centre non-interventional study we used continuous...
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HB-EGF-induced IL-8 secretion from airway. In the present study, we aimed to investigated the inflammatory cytokines secreted by bronchial epithelial cells following exposure to HB-EGF that promoted proliferation and migration of human lung fibroblast.. Methods: HB-EGF–induced inflammatory cytokines were assayed in two airway epithelial cells (primary human bronchial epithelial cells [HBECs] and BEAS-2B cells). Moreover, the culture supernatants derived from...
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Hospital admission trends due to respiratory diseases in England and Wales between 1999 and 2019: an ecologic study. Results: Hospital admission rate increased by 104.7% [from CI in 1999 to CI in 2019 per 100,000 persons, trend test, p <. The age group 75 years and above accounted for 34.1% of the total number of hospital admissions. Males contributed to...
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Magnesium isoglycyrrhizinate inhibits airway inflammation in rats with chronic obstructive pulmonary disease. In this study, we evaluated the anti-inflammatory effect of MgIG in rats with COPD and investigated the underlying mechanisms.. Methods: Rat model of COPD was constructed by endotracheal-atomized lipopolysaccharide exposure and cigarette smoke induction. Rats were randomly divided into 5 groups: control group, COPD model group, salmeterol flutica-...