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Chủ đề : Whole-genome sequence


Có 10+ tài liệu thuộc chủ đề "Whole-genome sequence"

Detection of copy number variants in African goats using whole genome sequence data

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A total of 6231 global CNV regions (CNVR) were found across all animals, representing 59.2 Mb (2.4%) of the goat genome. Deletions and insertions are referred to as unbal- anced SV because they result in changes in the length of the genome. Full list of author information is available at the end of the article. CNV cover about 4.5–9.8% of...

Genomic analysis of demographic history and ecological niche modeling in the endangered Chinese Grouse Tetrastes sewerzowi

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Genomic analysis of demographic history and ecological niche modeling in the. endangered Chinese Grouse Tetrastes sewerzowi. The Chinese grouse Tetrastes sewerzowi is a forest-dwelling species endemic to the mountains to the east of the Qinghai – Tibet Plateau, which has been listed as Near Threatened with a decreasing trend by the IUCN because of ongoing deforestation and fragmentation of coniferous...

Comparative genomic analysis of a Shiga toxin-producing Escherichia coli (STEC) O145:H25 associated with a severe pediatric case of hemolytic uremic syndrome in Davidson County, Tennessee, US

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O145:H25 associated with a severe pediatric case of hemolytic uremic syndrome in. Results: The STEC O145:H25 strain EN1I-0044-2 was isolated from a pediatric patient with diarrhea, HUS and severe neurologic and cardiorespiratory complications, who was enrolled in a previously reported case-control study of acute gastroenteritis conducted in Davidson County, Tennessee in 2013. The strain EN1I-0044-2 genome sequence contained a chromosome...

Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data

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Using whole genome sequence (WGS) data, we assess two methods for detecting mixed infection: (i) a combination of the number of heterozygous sites and the proportion of heterozygous sites to total SNPs, and (ii) Bayesian model-based clustering of allele frequencies from sequencing reads at heterozygous sites.. We found that both approaches were effective in distinguishing between pure strains and mixed...

Assessing runs of Homozygosity: A comparison of SNP Array and whole genome sequence low coverage data

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Assessing runs of Homozygosity: a comparison of SNP Array and whole genome sequence low coverage data. Background: Runs of Homozygosity (ROH) are genomic regions where identical haplotypes are inherited from each parent. By allowing heterozygous SNPs per window, using the PLINK homozygosity function and non-parametric analysis, we were able to obtain non-significant differences in number ROH, mean ROH size and...

Genome analysis of the foxtail millet pathogen Sclerospora graminicola reveals the complex effector repertoire of graminicolous downy mildews

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Genome analysis of the foxtail millet. Genes encoding jacalin-like lectin-domain-containing secreted proteins were enriched in S. Of a total of 1220 genes encoding putative secreted proteins, 91 significantly changed their expression levels during the infection of plant tissues compared to the sporangia and zoospore stages of the S. The likely source of the S. graminicola, with strict host specificity observed...

From genomes to genotypes: molecular epidemiological analysis of Chlamydia gallinacea reveals a high level of genetic diversity for this newly emerging chlamydial pathogen

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Background: Chlamydia (C.) gallinacea is a recently identified bacterium that mainly infects domestic chickens.. In this study, we conducted whole-genome sequencing of C. gallinacea strains and related chlamydial species.. In addition, a plasmid designated pJX-1, almost identical to p1274 of the type strain, except for two point mutations, was only found in field strains from chicken, but not in other...