Có 14+ tài liệu thuộc chủ đề "Runs of homozygosity"
tailieu.vn Xem trực tuyến Tải xuống
Runs of homozygosity analysis of South African sheep breeds from various. This study tested the hypothesis that production systems geared towards specific traits of importance or natural or artificial selection pressures influenced the occurrence and distribution of runs of homozygosity (ROH) in the South African sheep population. To get more insight into the autozygosity and distribution of ROH islands of...
tailieu.vn Xem trực tuyến Tải xuống
quantitative trait loci for economically important traits in Brown Swiss cattle. Across-cohort multi-trait meta-analyses of the results from the single-trait GWAS revealed 25 quantitative trait loci (QTL. Detected QTL explain between 2 and 10% of the variation in the estimated breeding values and thus may be considered as the most important QTL segregating in the Brown Swiss cattle breed. Furthermore,...
tailieu.vn Xem trực tuyến Tải xuống
Signatures of selection in the genome of Swedish warmblood horses selected for sport performance. Results: The genomic scan for homozygous regions identified long runs of homozygosity (ROH) shared by more than 85% of the genotyped SWB individuals. Long ROH were instead distributed evenly across the genome of Exmoor ponies in 77% of the chromosomes. Two population differentiation tests (F ST...
tailieu.vn Xem trực tuyến Tải xuống
Genome-wide data from the Bubi of Bioko Island clarifies the Atlantic fringe of the Bantu dispersal. Background: Bioko is one of the few islands that exist around Africa, the most genetically diverse continent on the planet. Results: We found that, genetically, the closest mainland population to the Bubi are Bantu-speaking groups from Angola instead the geographically closer groups from Cameroon....
tailieu.vn Xem trực tuyến Tải xuống
High-resolution population structure and runs of homozygosity reveal the genetic architecture of complex traits in the. In this study we derived the high-resolution population structure and levels of autozygosity of 377 Lipizzan horses originating from five different European stud farms utilizing the SNP genotype information of the high density 700 k Affymetrix Axiom ™ Equine genotyping array. Results: The high-resolution...
tailieu.vn Xem trực tuyến Tải xuống
Background: Natural and artificial selection leads to changes in certain regions of the genome resulting in selection signatures that can reveal genes associated with the selected traits. Annotation of the consensus regions of ROH and F ST windows revealed new and previously identified genes associated with traits of economic interest, such as APOB, IGF1, IGFBP2, POMC, PPARG, and ZNF423. Over-representation...
tailieu.vn Xem trực tuyến Tải xuống
Runs of homozygosity analysis reveals consensus homozygous regions affecting production traits in Chinese Simmental beef cattle. Background: Genomic regions with a high frequency of runs of homozygosity (ROH) are related to important traits in farm animals. We carried out a comprehensive analysis of ROH and evaluated their association with production traits using the BovineHD (770 K) SNP array in Chinese...
tailieu.vn Xem trực tuyến Tải xuống
In the present study, a gene dropping simulation was performed and inbreeding estimates based on runs of homozygosity (ROH), pedigree, and the genomic relationship matrix were compared to true inbreeding. Inbreeding based on ROH was estimated using SNP1101, PLINK, and BCFtools software with different threshold parameters. In the simulation, the longest individual ROH and the largest average length of ROH...
tailieu.vn Xem trực tuyến Tải xuống
Assessing runs of Homozygosity: a comparison of SNP Array and whole genome sequence low coverage data. Background: Runs of Homozygosity (ROH) are genomic regions where identical haplotypes are inherited from each parent. By allowing heterozygous SNPs per window, using the PLINK homozygosity function and non-parametric analysis, we were able to obtain non-significant differences in number ROH, mean ROH size and...
tailieu.vn Xem trực tuyến Tải xuống
It is worth noting that Mao et al. The iHS approach was developed by Voight et al. Two complementary approaches were ap- plied for the detection of selection signatures in the studied population, i.e., the ROH and iHS methods, which should boost the accuracy of detection and elim- inate unknown bias [26–28]. Kim et al. LTB4R-Blood 、 PTPN9-Muscle 、 MAN2C1-Blood...
tailieu.vn Xem trực tuyến Tải xuống
In this research, we focused on identifying genomic regions affected by different selection pressures, mainly highlighting the recent positive selection, as well as understanding the candidate genes and functional pathways associated with the signatures of selection in the Mangalarga Marchador genome. Conclusions: Our findings revealed evidence of signatures of selection in the MM breed that encompass genes acting on athletic...