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Chủ đề : Population genetics


Có 20+ tài liệu thuộc chủ đề "Population genetics"

Unravelling population structure heterogeneity within the genome of the malaria vector Anopheles gambiae

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heterogeneity within the genome of the malaria vector Anopheles gambiae. A recently separated species of the complex, An. Most notably, the frequencies of the largest and most geo- graphically distributed inversions in the second chromo- some of An. The goal of this dimen- sionality reduction is to preserve as much of the high dimensional population structure information in the low...

How imputation can mitigate SNP ascertainment Bias

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influenced by a non-random selection of the SNPs included in the used genotyping arrays. Full correction for this bias requires detailed knowledge of the array design process, which is often not available in practice. Results: The strategy was first tested by simulating additional ascertainment bias with a set of 1566 chickens from 74 populations that were genotyped for the positions...

DDRAD sequencing: An emerging technology added to the biosecurity toolbox for tracing the origin of brown marmorated stink bug, Halyomorpha halys (Hemiptera: Pentatomidae)

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Principal component analysis (PCA) of the identified SNPs indicated the existence of two main distinct genetic clusters representing individuals sampled from regions where BMSB is native to, China and Japan, respectively, and one broad cluster comprised individuals sampled from countries which have been invaded by BMSB. The population genetic structure analysis further discriminated the genetic diversity among the BMSB populations...

Fine-scale population structure and evidence for local adaptation in Australian giant black tiger shrimp (Penaeus monodon) using SNP analysis

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Fine-scale population structure and. evidence for local adaptation in Australian giant black tiger shrimp ( Penaeus monodon ) using SNP analysis. monodon populations.. Conclusion: This study provides new insights on genetic population structure of Australian P. Full list of author information is available at the end of the article. monodon from Western Australia was a separate genetic stock with reduced...

Mitochondrial and nuclear genetic analyses of the tropical black-lip rock oyster (Saccostrea echinata) reveals population subdivision and informs sustainable aquaculture development

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Mitochondrial and nuclear genetic analyses of the tropical black-lip rock oyster. These occurred at either side of the Wessel Islands and were termed (3. Three candidate adaptive SNPs were identified as occurring within known genes and gene ontology was well described for the sex peptide receptor gene.. 2019 Open Access This article is distributed under the terms of the Creative...

Whole-genome DNA similarity and population structure of Plasmodiophora brassicae strains from Canada

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population structure of Plasmodiophora brassicae strains from Canada. Information on genetic similarity among pathogen populations across Canada could be useful in estimating the genetic variation in pathogen populations, predicting the effect of subsequent selection pressure on changes in the pathogen population over time, and even in identifying the origin of the initial pathogen introduction to canola in Alberta.. Similarly, at...

Genome-wide data from the Bubi of Bioko Island clarifies the Atlantic fringe of the Bantu dispersal

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Genome-wide data from the Bubi of Bioko Island clarifies the Atlantic fringe of the Bantu dispersal. Background: Bioko is one of the few islands that exist around Africa, the most genetically diverse continent on the planet. Results: We found that, genetically, the closest mainland population to the Bubi are Bantu-speaking groups from Angola instead the geographically closer groups from Cameroon....

Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus

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Results: Here, we present a genome-wide analysis of two genetic crosses between ivermectin resistant and sensitive isolates of the parasitic nematode Haemonchus contortus, an economically important gastrointestinal parasite of small ruminants and a model for anthelmintic research. 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0. 6 Department of Comparative...

Comparative analysis reveals the Genomic Islands in Pasteurella multocida population genetics: On Symbiosis and adaptability

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Genomic Islands (GIs) are one of the most important mobile components that quickly help bacteria acquire large fragments of foreign genes. multocida are unknown in the evolution of bacterial populations.. multocida , the GIs accounted for 5.8% of the core genes in the pan-genome, mainly related to functional metabolic activities. multocida evolution and adaptation to the environment are reflected by...

Genetic ancestry, admixture and health determinants in Latin America

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Background: Modern Latin American populations were formed via genetic admixture among ancestral source populations from Africa, the Americas and Europe. We are interested in studying how combinations of genetic ancestry in admixed Latin American populations may impact genomic determinants of health and disease. Results: We analyzed a total of 347 admixed Latin American genomes along with 1102 putative ancestral source...

Microsatellite development from genome skimming and transcriptome sequencing: Comparison of strategies and lessons from frog species

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Background: Even though microsatellite loci frequently have been isolated using recently developed next-generation sequencing (NGS) techniques, this task is still difficult because of the subsequent polymorphism screening requires a substantial amount of time. Results: The results revealed that the number of isolated microsatellites increases with increased data quantity and read length. Larger k-mer sizes produced fewer total number of microsatellite...

Development of polymorphic microsatellite markers by using de novo transcriptome assembly of Calanthe masuca and C. sinica (Orchidaceae)

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Simple sequence repeats (SSRs) are useful for genetic diversity analysis, presumably providing key information for the study and preservation of the wild populations of the two species we are interested in.. masuca and C. Molecular evolutionary analysis revealed functional pathways commonly enriched in unigenes with similar evolutionary rates in the two species, as well as pathways specific to each species,...

Evaluation of whole exome sequencing as an alternative to BeadChip and whole genome sequencing in human population genetic analysis

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The largest publicly accessible set of human genomic sequence data available today originates from exome sequencing that comprises around 1.2% of the whole genome (approximately 30 million base pairs).. Results: To unbiasedly compare the effect of SNP selection strategies in population genetic analysis we subsampled the variants of the same highly curated 1 K Genome dataset to mimic genome, exome...

Evidence of peripheral olfactory impairment in the domestic silkworms: Insight from the comparative transcriptome and population genetics

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impairment in the domestic silkworms:. Comparison of the same sex between the domestic and wild silkworms revealed 1410 and 1173 differentially expressed genes (DEGs) in males and females, respectively. Furthermore, one deleterious mutation was found in OR30 of the domestic population, which was located in transmembrane helix 6 (TM6).. Conclusions: Our results suggested that down-regulation of the olfactory-related genes and...

Lecture Principles of Biology - Chapter 23: Population Genetics

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frequencies or genotype frequencies in a population over time. Genetic equilibrium in populations: the Hardy-Weinberg theorem. Microevolution is deviation from Hardy- Weinberg equilibrium. Genetic variation must exist for natural selection to occur. Explain what terms in the Hardy- Weinberg equation give:. allele frequencies (dominant allele, recessive allele, etc.). Microevolution is a change in allele frequencies or genotype frequencies in a...