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ATP-binding cassette

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Structural and functional insights into the Diabrotica virgifera virgifera ATP-binding cassette transporter gene family

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Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. Functional analysis of the ATP-binding cassette (ABC) transporter gene family of Tribolium castaneum. Mutational analysis of the traffic Atpase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster - implications for structure-function-relationships. The ABCs of Eye Color in Tribolium castaneum: Orthologs of the Drosophila white, scarlet, and brown Genes.

Phylogenetic analysis of the ATP-binding cassette proteins suggests a new ABC protein subfamily J in Aedes aegypti (Diptera: Culicidae)

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A Survey of the ATP-Binding Cassette (ABC) Gene Superfamily in the Salmon Louse (Lepeophtheirus salmonis). Phylogenetic analysis of the ATP-binding cassette transporter family in three mosquito species. Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance- associated protein family. D V: Peroxisomal ABC transporters.

Genome-wide analysis of ATP-binding cassette transporter provides insight to genes related to bioactive metabolite transportation in Salvia miltiorrhiza

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Whole-transcriptome survey of the putative ATP-binding cassette (ABC) transporter family genes in the latex- producing laticifers of Hevea brasiliensis. Tomato ATP-binding cassette transporter SlABCB4 is involved in auxin transport in the developing fruit. The Arabidopsis concentration-dependent influx/efflux transporter ABCB4 regulates cellular auxin levels in the root epidermis

Genome-wide identification of ATP binding cassette (ABC) transporter and heavy metal associated (HMA) gene families in flax (Linum usitatissimum L.)

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The ABC transporter structure and mechanism:. functional and structural aspects of the ATP-hydrolyzing subunits/domains.. In silico genome-wide analysis of the ATP-binding cassette transporter gene family in soybean ( Glycine max L.) and their expression profiling. Genome-wide identification, evolution, and expression analysis of the ATP-binding cassette transporter gene family in Brassica rapa . Plant cuticular lipid export requires an ABC transporter.

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Periplasmic binding proteins and ABC system • ABC transport systems (ATP-binding cassette): ATP-dependent active transport found in various gram-negative bacteria • Involve substrate-specific binding proteins located in the bacterial periplasm, the gel-like substance between the bacterial cell wall and cytoplasmic membrane • Often involved in uptake of organic compounds (sugars, amino acids. inorganic nutrients (sulfate and phosphate ) and certain metal • Characteristic of periplasmic binding proteins

Genome-wide identification and geneediting of pigment transporter genes in the swallowtail butterfly Papilio xuthus

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Genome-wide identification and characterization of ATP-binding cassette transporters in the silkworm, Bombyx mori

Comparative transcriptome analysis of the newly discovered insect vector of the pine wood nematode in China, revealing putative genes related to host plant adaptation

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In the present study, detoxification-related DEGs were identified, including 11 cytochrome P450 monooxygenases (P450s), three UDP- glycosyltransferases (UGTs), seven carboxylesterases (CEs), and 14 ATP-binding cassette (ABC) transporters (Fig. Among which, ten P450s, two UGTs, six CEs, and eight ABC transporters were upregulated in the population feeding on P.

Growth inhibition of Spodoptera frugiperda larvae by camptothecin correlates with alteration of the structures and gene expression profiles of the midgut

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Transcriptional response of ATP-binding cassette (ABC) transporters to insecticides in the cotton bollworm, Helicoverpa armigera. Identification and transcriptional response of ATP-binding cassette transporters to chlorantraniliprole in the rice striped stem borer, Chilo suppressalis. Chitin is a necessary component to maintain the barrier function of the peritrophic matrix in the insect midgut.

The complete genome sequence of the nitrile biocatalyst Rhodococcus rhodochrous ATCC BAA-870

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Nu- merous components of the ubiquitous transporter fam- ilies, the ATP-Binding Cassette (ABC) superfamily and the Major Facilitator Superfamily (MFS), are present in Rhodococcus strain BAA-870. rhodochrous ATCC BAA-870 has 81 members of the MFS, mostly from the phthalate permease and sugar transporter families. rhodochrous ATCC BAA-870 include at least 122 members of the ABC superfamily, which in- cludes both uptake and efflux transport systems. rhodochrous ATCC BAA-870. rho- dochrous ATCC BAA-870

Predicting tumor response to drugs based on gene-expression biomarkers of sensitivity learned from cancer cell lines

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ABCB1 encodes ATP binding cassette subfamily B member 1, a member of the superfamily of ATP-binding cassette (ABC) transporters. Many of the most frequently selected genes were also known targets of the drugs (additional file 2: Table S2).. The drug nutlin-3a inhibits the interaction between p53 and MDM2, leading to activation of the p53 pathway [31]. BCL2 was selected in almost 100% of the predictive gene sets for sensitivity to venetoclax.

Comparative and functional genomics of the ABC transporter superfamily across arthropods

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Functional analysis of the ATP-binding cassette (ABC) transporter gene family of Tribolium castaneum.. https://doi.org/10.1093/bioinformatics/btaa1022.. https://doi.org/10.1093/molbev/mst010.. https://doi.org/10.1093/bioinformatics/btp348.. https://doi.org/10.1126/science.1257570.. https://doi.org X.12628.. https://doi.org/10.1038/s . https://doi.org/10.1093/bioinformatics/btp352.. https://doi.org/10.1002/arch.21650.. https://doi.org/10.101 6/J.IBMB . https://doi.org/10.1098/rspb.2020.1311.. https

Genome-wide association study (GWAS) reveals genetic loci of lead (Pb) tolerance during seedling establishment in rapeseed (Brassica napus L.)

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In Arabi- dopsis AtACBP1 (Acyl-CoA-binding domain-containing protein), AtPSAE1 (Photosystem I reaction center subunit IV A) and several ABC (ATP-binding cassette) transporter genes (AtATM3, AtPDR8, and AtPDR12) have been identi- fied as being involved in tolerance to Pb stress [24–27].

Transcriptome analysis uncovers the key pathways and candidate genes related to the treatment of Echinococcus granulosus protoscoleces with the repurposed drug pyronaridine

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Expression of ATP-binding cassette multidrug transporters in the giant liver fluke Fasciola gigantica and their possible involvement in the transport of bile salts and anthelmintics. Heat shock protein (HSP) drug discovery and development: Targeting heat shock proteins in disease. Characterization of a putative hsp70 pseudogene transcribed in protoscoleces and adult worms of Echinococcus granulosus. Heat shock protein 90 inhibitors as broad spectrum anti-infectives.

Differences in midgut transcriptomes between resistant and susceptible strains of Chilo suppressalis to Cry1C toxin

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Single amino acid mutation in an ATP-binding cassette transporter gene causes resistance to Bt toxin Cry1Ab in the silkworm, Bombyx mori. RNAi in the striped stem borer, Chilo suppressalis, establishes a functional role for aminopeptidase N in Cry1Ab intoxication. Midgut transcriptome response to a cry toxin in the diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae).

Whole genome resequencing reveals an association of ABCC4 variants with preaxial polydactyly in pigs

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ABCC4, a member of the ATP-binding cassette trans- porter family is also known as multidrug resistance- associated protein 4 (MRP4) [50].

Transcriptome sequencing of a keystone aquatic herbivore yields insights on the temperature-dependent metabolism of essential lipids

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The higher expression levels of fatty acid trans- porters was accompanied by the expression of a transporter in the category ‘inorganic ion transport and metabolism’ (P), as well as by ABC transport proteins (ATP-Binding Cassette sub-family C/ member 4) and cyto- chrome P450 305a1, which are involved prostaglandin- mediated signalling (Q, secondary metabolites).. High levels of dynein, myosin, and tubulin (Z) indicate a remodelling of the cytoskeleton at lower temperatures..

Transcriptomic insights into the effects of CytCo, a novel nematotoxic protein, on the pine wood nematode Bursaphelenchus xylophilus

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Validation of RNA-seq expression data by RT-qPCR Nine DEGs in PWNs treated with the CytCo protein for 24 h, as per transcriptomic analysis were selected for further validation: the upregulated cuticle collagen (BXY_1699200) and ATP-binding cassette transporter (BXY_0203900) (Tables S4 and S5), and the downregu- lated major sperm protein (BXY_0820100), cathepsin (BXY_0408100), cytochrome P450 (BXY_0076600), serine carboxypeptidase (BXY_0963400), arginine kinase (BXY_1237900), elongation of very long

Deploying new generation sequencing for the study of flesh color depletion in Atlantic Salmon (Salmo salar)

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With regard to to ATP-binding cassette, sub family, Zoric [83] reported that a missense mutation in abcg2-1a, resulting in the substitution of Asparagine with Serine in amino acid position 230 (Asn230Ser), is predicted to be associated with flesh color in Atlantic salmon because it is more prevalent in the pale than in the dark flesh phenotype.

Host plant adaptation in the polyphagous whitefly, Trialeurodes vaporariorum, is associated with transcriptional plasticity and altered sensitivity to insecticides

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Multiple ATP-binding cassette transporters are involved in insecticide resistance in the small brown planthopper, Laodelphax striatellus. Comparative analysis of the UDP- glycosyltransferase multigene family in insects. UDP-Glycosyltransferase genes in the striped rice stem borer, Chilo suppressalis (Walker), and their contribution to chlorantraniliprole resistance. Constitutive overexpression of the cytochrome P450 gene CYP6A1 in a house fly strain with metabolic resistance to insecticides.

Physiological and transcriptomic analyses reveal the roles of secondary metabolism in the adaptive responses of Stylosanthes to manganese toxicity

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Among them, a set of genes en- coding homologs to ATP-binding cassette (ABC) transporters were regulated by Mn toxicity. Therefore, genes encoding ABC trans- porters are probably involved in stylo leaves defense against Mn toxicity.. Furthermore, genes encoding cation/H + exchangers were found to be up-regulated by Mn toxicity in this.