« Home « Kết quả tìm kiếm

Brain metastases

Tìm thấy 20+ kết quả cho từ khóa "Brain metastases"

The risk and prognostic factors for brain metastases in esophageal cancer patients: An analysis of the SEER database

tailieu.vn

Results showed homogeneous and heteroge- neous associated factors for brain metastases develop- ment and prognosis. The nomogram had good performance for predicting brain metastases develop- ment. Imaging examination of the central nervous sys- tem should be considered for esophageal cancer patients with a high brain metastases risk.. BrM: Brain metastases.. Brain metastases from esophageal squamous cell carcinoma: clinical characteristics and prognosis.

Preoperative stereotactic radiosurgery for brain metastases: The STEP study protocol for a multicentre, prospective, phase-II trial

tailieu.vn

Epidemiology of brain metastases. https://doi.org/10.1007/s y.. Management of brain metastases. https://doi.org/10.1053/j.seminoncol . The management of brain metastases. https://doi.org/10.1016/S . https://doi.org/10.1016/j.canrad . https://doi.org/10.1093/neuros/. https://doi.. Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial. https://doi.org/1 0.1001/jama .

The incidence, risk factors and predictive nomograms for early death of lung cancer with synchronous brain metastasis: A retrospective study in the SEER database

tailieu.vn

Conclusions: We established a comprehensive nomogram to predict early death in lung cancer patients with synchronous brain metastases. Keywords: Lung cancer, Brain metastases, Nomogram, Early death. Currently, there is no reliable treatment for lung cancer with synchronous brain metastasis (LCBM).. Death within a short period of time after diagnosis is defined as early death. And many patients with LCBM die early death due to intracranial hypertension and tumor-related epilepsy [12].

Phase II trial of nab-paclitaxel in metastatic breast cancer patients with visceral metastases

tailieu.vn

Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer. https://doi.org CCR-10-1564.. https://doi.org/10.1016/j.pneurobio . Shah N, Mohammad AS, Saralkar P, Sprowls SA, Vickers SD, John D, et al.. Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases. https://doi.org/10.1016/j.phrs

A new nomogram and risk classification system for predicting survival in small cell lung cancer patients diagnosed with brain metastasis: A large population-based study

tailieu.vn

Pembrolizumab for patients with melanoma or non-small-cell lung cancerand untreated brain metastases: early analysis of a non-randomised, open-label, phase 2 trial. https://doi.org/1 0.1016/S . https://doi.org/10.1016/. Tumor infltrating lymphocytes and PD-L1 expression in brain metastases of small cell lung cancer (SCLC). https://doi.. org/10.1007/s . https://doi.org/10.1111/j.14 64-410X x..

Clinicopathological characteristics and survival outcomes in patients with synchronous lung metastases upon initial metastatic breast cancer diagnosis in Han population

tailieu.vn

Risk factors and survival of patients with liver metastases at initial metastatic breast Cancer diagnosis in Han population. Incidence, risk factors and survival of patients with brain metastases at initial metastatic breast cancer diagnosis in China. Development and validation of a nomogram for predicting survival of advanced breast cancer patients in China. Breast cancer subtypes predispose the site of distant metastases.

Spatial and space-time clusters of brain tumor and CNS incidence and mortality in the contiguous USA: 2000–2014

tailieu.vn

Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma

An open-label expanded access program of afatinib in EGFR tyrosine kinase inhibitornaïve patients with locally advanced or metastatic non-small cell lung cancer harboring EGFR mutations

tailieu.vn

In patients with brain metastases (n = 27), median PFS was 14.0 months (95% CI 11.0–. 22.1 months. In patients with brain metastases and common EGFR mutations (n = 24), median PFS was 14.1 months (95% CI 11.7–22.8 months). The ORR in patients with brain metastases was 89%. In patients with un- common EGFR mutations (any uncommon mutation:.

Chapter 085. Neoplasms of the Lung (Part 15)

tailieu.vn

Usually, in addition to radiotherapy for brain metastases and cord compression, dexamethasone (25–100 mg/d in four divided doses) is also given and then rapidly tapered to the lowest dosage that relieves symptoms.. Because of the high frequency of brain metastases, the use of prophylactic cranial irradiation (PCI, given to the whole brain before metastatic disease becomes manifest) has been considered.

Prognostic factors of brain metastasis and survival among HER2-positive metastatic breast cancer patients: A systematic literature review

tailieu.vn

Breast cancer brain metastases:. Lin NU, Dieras V, Paul D, et al. Murthy R, Borges VF, Conlin A, Chaves J, Chamberlain M, Gray T, et al.. Murthy RK, Loi S, Okines A, et al. Modi S, Saura C, Yamashita T, et al. Freedman RA, Gelman RS, Anders CK, Melisko ME, Parsons HA, Cropp AM, et al. Kim ES, Bruinooge SS, Roberts S, Ison G, Lin NU, Gore L, et al

Chapter 083. Cancer of the Skin (Part 7)

tailieu.vn

Melanoma can metastasize to any internal organ, the brain being a particularly common site. Metastatic melanoma is generally incurable, with survival in patients with visceral metastases generally <1 year. Patients with soft tissue and nodal metastases fare better than those with liver and brain metastases. Metastases limited to regional nodes (AJCC stage III disease) warrant a therapeutic lymph node dissection..

Feasibility and effectiveness of afatinib for poor performance status patients with EGFR-mutation-positive non-small-cell lung cancer: A retrospective cohort study

tailieu.vn

This outcome could be explained by the finding that afatinib is effective for patients with bone and brain metastases [18]. Systemic treatments other than TKIs are effective in patients with good PS without brain me- tastasis. however, in the absence of brain metastasis, the outcomes of patients with poor PS in our study might not be comparable to that of patients with good PS in other studies [18]. Table 2 Univariate and multivariate analysis of prognostic factors in patients (PFS).

Chapter 081. Principles of Cancer Treatment (Part 6)

tailieu.vn

Radiation therapy can also palliate disease symptoms in a variety of settings: relief of bone pain from metastatic disease, control of brain metastases, reversal of spinal cord compression and superior vena caval obstruction, shrinkage of painful masses, and opening of threatened airways. In high-risk settings, radiation therapy can prevent the development of leptomeningeal disease and brain metastases in acute leukemia and lung cancer..

Association between oligo-residual disease and patterns of failure during EGFR-TKI treatment in EGFR-mutated non-small cell lung cancer: A retrospective study

tailieu.vn

Previous studies have suggested that patients with brain metastases have a higher risk of developing newer brain metastases and have a poorer prognosis [31]. ECOG PS 0 – 1 and having one metastatic organ at baseline were independent predictive factors of oligo-residual disease in patients with EGFR-mutated NSCLC.

Chapter 085. Neoplasms of the Lung (Part 17)

tailieu.vn

Cranial radiation often decreases the signs and symptoms of brain metastases. In the case of symptomatic, progressive lesions in the chest or at other critical sites, if radiotherapy has not yet been given to these areas, it may be administered in full doses (e.g., 40 Gy to the chest tumor mass).. Often this histologic diagnosis is made in some patients only on review of the resected surgical specimen.

Brigatinib versus other second-generation ALK inhibitors as initial treatment of anaplastic lymphoma kinase positive non-small cell lung cancer with deep phenotyping: Study protocol of the ABP trial

tailieu.vn

The variance minimization method will be used for patient allocation, adjusting for the confounders brain metastases (presence vs. Overall, 58 patients will be enrolled per treatment arm..

Efficacy of osimertinib for preventing leptomeningeal metastasis derived from advanced EGFR-mutated non-small cell lung cancer: A propensity-matched retrospective study

tailieu.vn

Comparative analysis of first-line treatment regimens for advanced EGFR-mutant non-small cell lung cancer patients with stable brain metastases. https://doi.org/10.21037/apm-20-1136..

The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma

tailieu.vn

In contrast with the potential role of APC/CTNNB1 mutations in established brain metastases from other solid cancers [38], our results show rare (5%) activa- tion of β-catenin. We thus conclude that al- though APC/CTNNB1 mutations may contribute to the development of parenchymal brain metastases, melanoma-intrinsic β-catenin signaling plays a less significant role..

Chapter 085. Neoplasms of the Lung (Part 16)

tailieu.vn

Patients with brain metastases, hemoptysis, and bleeding disorders or who need anticoagulation are also not eligible to receive the agent. Clinical responses have been seen in a large fraction of the small subset of patients with tumors bearing mutations in the EGFR.. Patients with limited stage disease have high response rates (60–80%) and a 10–30% complete response rate.. The response rates in patients with extensive disease are somewhat lower (50%) and almost always partial responses.

Đánh giá chất lượng cuộc sống người bệnh ung thư phổi di căn não được điều trị xạ phẫu Gamma Knife tại Bệnh viện K

tailieu.vn

Foroni et al, (2005), Analysis of long-term outcomes and prognostic factors in patients with non-small cell lung cancer brain metastases treated by gamma knife radiosurgery, J Neurosurg, 102 Suppl, tr. Natvig et al, (2017), Predictors of quality of life and survival following Gamma Knife surgery for lung cancer brain metastases: a prospective study, J Neurosurg . et al, (2012), Quality of life in patients with brain metastases using the EORTC QLQ-BN20 and QLQ-C30, J.