« Home « Kết quả tìm kiếm

Electrospray ionization

Tìm thấy 20+ kết quả cho từ khóa "Electrospray ionization"

Impurity profiling of morphine by liquid chromatography-heated electrospray ionization mass spectrometry (LC-HESI-MS)

tailieu.vn

Impurity profiling of morphine by liquid chromatography-heated electrospray ionization mass spectrometry (LC-HESI-MS). Systematic optimization of the chromatographic conditions was carried out using design of experiments.

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 42)

tailieu.vn

Determina- tion of six penicillins in bovine tissues by liquid chromatography-electrospray ionization tandem mass spectro- metry. 13) Fagerquist CK, Lightfield AR (2003) Confirmatory analysis of beta-lactam antibiotics in kidney tissue by liquid chromatography/electrospray ionization selective reaction monitoring ion trap tandem mass spectrometry.. 14) Holstege DM, Puschner B, Whitehead G et al. 15) Ito Y, Ikai Y, Oka H et al.

Tách chiết, phân lập Cephalotaxine và Homoharringtonine từ cây Cephalotaxus

tailieu.vn

Nghiên cứu này nhằm mục đích để tách chiết, phân lập cephalotaxine và homoharingtonine từ cây Cephalotaxus harringtonia bằng cách sử dụng kết hợp các phương pháp sắc ký cột và phương pháp phân tích hiện đại HPLC. (2003), “HPLC-electrospray ionization-MS-MS analysis of Cephalotaxus harringtonia leaves and enhancement of the extraction efficiency of alkaloids therein by SFE”, J. (1972), “Antitumor alkaloids from Cephalotaxus harringtonia: Structure and activity”, Journal of Pharmaceutical Science .

Biochemistry, 4th Edition P15

tailieu.vn

FIGURE 5.13 The three principal steps in electrospray ionization mass spectrometry (ESI-MS). digestion of a specific protein spot on the gel and injection of the digest into the HPLC/tandem MS, gives sequence information that can be used to identify specific proteins. The measured masses of the proteolytic frag- ments can be compared to databases (see following discussion) of peptide masses of known sequence.

Introduction to Modern Liquid Chromatography, Third Edition part 64

tailieu.vn

The use of TFA as buffer with mass-spectrometric detection (LC-MS) can be problematic when using electrospray ionization. This problem can be alleviated by the postcolumn addition of a weaker, less volatile acid such as propionic acid [17]. For modern, type-B alkylsilica columns, peak tailing at low pH usually depends on the weight of injected peptide, with a resulting overloading of the column (due to the mutual repulsion of positively charged solute ions in the stationary phase.

Make-up Solvent Considerations for Prep and Semi-Prep LC/MS Mass-Based ....

tailieu.vn

Solvent choices for electrospray ionization can be separated from those of column separation for systems utilizing a make-up solvent technique to provide required dilution. Main Components: Gilson-Thermo Finnigan NEBULA™ Prep System, consisting of a Gilson 215 Liquid Handler/Autosampler/Fraction Collector, 322 H2 Prep Pump, 307 Make-up Pump, 155 UV/VIS Dual- wavelength Detector with 0.2-mm flow cell, and Thermo Finnigan MSQ Mass Spectrometer..

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 28)

tailieu.vn

J Chromatogr B Igarashi K, Shigee Y, Kasuya F et al. (1997) Analysis of haloperidol and its neurotoxic pyridinium metabolite in. 17) Hoja H, Marquet P, Verneuil B et al. (1997) Determination of haloperidol and its reduced metabolite in human plasma by liquid chromatography-mass spectrometry with electrospray ionization

Synthesis, solvatochromism, and biological activity of novel azo dyes bearing 2-pyridone and benzimidazole moieties

tailieu.vn

Mass spectra and MS 2 spectra were obtained by the use of electrospray ionization in the positive ionization mode.. 4-(1 H -Benzo[d]imidazol-2-yl)aniline was synthesized from o -phenylenediamine and p-aminobenzoic acid in the presence of an acid as a dehydrating agent. 1 H NMR (DMSO-d 6 ) δ /ppm:. Both azo compounds were synthesized according to the procedure described as published before 35 starting from 4-(1H-benzo[d]imidazol-2-yl)aniline.

Phytochemical characterisation of Phlomis linearis Boiss. & Bal and screening for anticholinesterase, antiamylase, antimicrobial, and cytotoxic properties

tailieu.vn

Structural characterization of flavonol 3, 7-di-O-glycosides and determination of the glycosylation position by using negative ion electrospray ionization tandem mass spectrometry. Journal of Mass Spectrometry 2006. Journal of Agricultural and Food Chemistry 2005. Journal of Chromatography A 2000. Journal of Essential Oil Research 2020. Journal of Agricultural and Food Chemistry 2017. Chemical composition and antimicrobial activity of the essential oil of Phlomis ferruginea Ten.

Evaluation of Asparagus adscendens accessions for root yield and shatavarin IV content in India

tailieu.vn

The quantitative analysis of shatavarin IV was performed with Thermo Fisher Scientific made Quantum Access MAX triple stage quadrupole mass spectrometer (Thermo Fisher Scientific, Waltham, MA, USA) with a heated electrospray ionization (HESI) source. A Dionex UltiMate 3000 Rapid Separation’s made ultrahigh-performance liquid chromatograph (UHPLC) system equipped with an autosampler, a quaternary pump system and column compartment was used for separation of the shatavarin IV..

Proteomic profiling of multidrug-susceptible and resistant strains of Mycobacterium tuberculosis

tailieu.vn

Identification of Mycobacterium tuberculosis H37Rv integral membrane proteins by one­dimensional gel electrophoresis and liquid chromatography electrospray ionization tandem mass spectrometry. Zheng J., Liu L., Wei C., Leng W., Yang J., et al., 2012. A comprehensive proteomic analysis of Mycobacterium bovis bacillus Calmette­Guerin using high resolution Fourier transform mass spectrometry.

HPLC for Pharmaceutical Scientists 2007 (Part 13)

tailieu.vn

Merkle, The effects of sample prepa- ration methods on the variability of the electrospray ionization response for model drug compounds, Rapid Commun. Herman, Generic method for on-line extraction of drug substances in the presence of biological matrices using turbulent flow chromatography, Rapid Commun. Sheinin, Analytical procedures and method validation: Highlights of the FDA’s draft guidance, LCGC .

Luận văn Thạc sĩ Hoá học: Nghiên cứu chiết tách, xác định cấu trúc một số hợp chất chính từ cây cà độc dược (Datura metel)

tailieu.vn

Phổ khối lượng (MS): Phổ khối lượng được ghi trên máy Agilent 1200 HPLC-MSD với nguồn ion hóa Electrospray ionization source-ESI hoặc Atmospheric pressure chemical ionization-APCI của Viện Hóa học các Hợp chất thiên nhiên, Viện Hàn lâm Khoa học và Công nghệ Việt Nam.. Điểm nóng chảy được đo trên máy Kofler micro-hotstage Viện Hóa học các Hợp chất thiên nhiên, Viện Hàn lâm Khoa học và Công nghệ Việt Nam.. Chi tiết quá trình phân lập các hợp chất từ că ̣n chiết MeOH của loài D..

Nghiên cứu xác định Oxalat trong mẫu thực phẩm bằng phương pháp điện di mao quản sử dụng Detector đo độ dẫn không tiếp xúc

repository.vnu.edu.vn

Ruben Rellan-Alvarez (2011), ―Development of a new high-performance liquid chromatography-electrospray ionization time-of-flight mass spectrometry method for the determination of low molecular mass organic acid in plant tissue extracts‖, J.Agric. Verónica Galli, Coral Barbas Capillary electrophoresis for the analysis of short-chain organic acid in coffee‖, Journal of Chromatography A, 1032:.

Neurochemical Mechanisms in Disease P81

tailieu.vn

In mucopolysaccharidosis type I, the analysis of the levels of oligosaccharides derived from GAGs in cultured fibroblasts (as measured by electrospray ionization tandem mass spectrometry) combined with the residual α -L-iduronidase activity have been shown to distinguish patients with and without CNS involvement (Fuller et al., 2005).

HPLC for Pharmaceutical Scientists 2007 (Part 19)

tailieu.vn

Nagabhushan, Structural analysis of the CHO-derived interleukin-4 by liquid-chromatography/electrospray ionization mass spectrometry, J. Cohen, Timeline: Protein kinases—The major drug targets of the twenty-first centry? Nature Rev. Lodish, Analysis of receptor signaling pathways by mass spectrometry: Identifi- cation of Vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors, Proc. Sudarsanam, The protein kinase complement of the human genome, Science .

Comparison of Chilean honeys through MALDI-TOF-MS profiling and evaluation of their antioxidant and antibacterial potential

tailieu.vn

Another technique applied successfully to characterize and to detect adulterant components in honey is the matrix-assisted laser desorp- tion/ionization mass spectrometry (MALDI-MS) technique (Qu et al., 2019). MALDI is one of the two “ soft ” ionization techniques besides electrospray ionization (ESI) which allow for the sensitive detection of diverse molecules by mass spectrometry (Hillenkamp and Peter- Katalinic, 2014).

Chuyen de Phuong phap LC-MS (1)

www.academia.edu

Ngày nay, ph−ơng pháp LC-MS đã 1 Chuyên đề “Ph−ơng pháp LC-MS phân tích các hợp chất hữu cơ” phát triển thành một ph−ơng pháp phân tích hiện đại với các bộ kết nối ion hoá hoá học ở áp suất khí quyển (APCI, Atmospheric-Pressure Chemical Ionization), bộ kết nối ion hóa phun điện (ESI, Electrospray Ionization Interface) cho phép xác định các phân tử có khối l−ợng phân tử lớn, nh− các chất protein, peptit và oligonucleotit và các phân tử này có thể là các ion đa điện tích sử dụng phổ biến trong các

Introduction to Modern Liquid Chromatography, Third Edition part 63

tailieu.vn

Most important, aqueous-organic mobile phases are compatible with electrospray ionization, so RPC is almost always the technique used with detection by mass spectrometry (Section 4.14.1.1). 13.4.1.1 Column Selection. The average selectivity of columns with different ligands is summarized in Table 5.8a and the related text, including values of the column-hydrophobicity parameter H. The most popular columns are based on straight-chain alkyl groups (C 4 , C 8 , C 18.

Electrochemical oxidation of curcuminoids: An experimental and computational investigation

tailieu.vn

Formation of C-E-P1 is also witnessed by electrospray ionization mode (ESI)-mass analysis providing. Electrochemical investigations additionally demonstrated the reversible oxidation and reduction processes observed with anodic peak III and cathodic peak IV that unambiguously depict the formation of the ortho-dioxophenyl-containing product (9) and its reduction to the corresponding catechol (8).