Có 20+ tài liệu thuộc chủ đề "phân tích hoá học"
tailieu.vn Xem trực tuyến Tải xuống
Câu 9 phân tích đặc điểm các phản ứng chuyển hoá thuốc ở pha 1?. Chất A có thể có hoặc ko có hoạt tính sinh ra chất B có thể có hoặc ko có hoạt tính chất C,D dếu là chất ko có hoạt tính sinh học .Một chát mẹ A sinh ra các hất chuyển hoá B or...
tailieu.vn Xem trực tuyến Tải xuống
4.7 Areas of the peaks and data treatment software 105. 15.10 Shielding and deshielding of the nuclei 342. 17.9 Advantages and limitations of the ELISA test in. 22.4 Confidence interval of the mean 506. (b) introduction of the sample. (d) recovery of the products following separation.. In an ideal case, t R is independent of the quantity injected.. (a) The...
tailieu.vn Xem trực tuyến Tải xuống
14.3 DISSOCIATION OF THE SAMPLE INTO ATOMS OR IONS 311. 14.3 Dissociation of the sample into atoms or ions. For the solution, a pump regulates the flow of the aerosol. Details of the spark chamber in the open position. The uncertainty E 2 leads to an imprecision of the corresponding wavelength.. The images of the entrance aperture 2 are in...
tailieu.vn Xem trực tuyến Tải xuống
Các cân bằng trong dung dịch. hàm lƣợng các dung dịch phân tích.. Mô tả sự điện ly trong dung dịch.. Sự điện ly trong dung dịch.. Sự điện ly trong dung dịch 1.1.1. Ví dụ: dung dịch HCl, NaCl. Còn những dung dịch FeCl 2 , Cu(OH) 2. Hằng số phân ly dung dịch 1.1.2.1. trong dung dịch phân...
tailieu.vn Xem trực tuyến Tải xuống
see also Selectivity. see also Multidimensional HPLC;. see also. see also DryLab. see Detectors,. see Detectors, conductivity. see Detectors, charged-aerosol. see also Data. see also Error, sources. see also Sample. see also Calibration, limits. see also Calibration,. see Detectors, UV. see also Computer-simulation software gradient optimization, 483–485 isocratic predictions from gradient data,. see also Dwell volume Dwell volume . see...
tailieu.vn Xem trực tuyến Tải xuống
INTRODUCTION TO MODERN LIQUID. A John Wiley &. Sons, Inc., Publication. Copyright © 2010 by John Wiley &. Sons, Inc. Published by John Wiley &. Sons, Inc., Hoboken, New Jersey.. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except...
tailieu.vn Xem trực tuyến Tải xuống
3.6.4.1 Column Switching Fraction Collectors Waste Diversion, 124 3.7 Column Ovens, 125. 3.10.1 System-Performance Tests Installation Qualification,. 3.10.2 Preventive Maintenance, 138. 3.10.2.1 Periodic Maintenance Suggestions for Routine. 3.10.3.1 Personnel Record Keeping Specific Repair. 4.9 Chemiluminescent Nitrogen Detector, 174 4.10 Chiral Detectors, 175. 5.1 Introduction, 200 5.2 Column Supports, 200. 5.3.3 Column Functionality (Ligand Type), 225 5.4 Column Selectivity, 227. 5.4.4.3...
tailieu.vn Xem trực tuyến Tải xuống
with Michael Swartz 12.1 Introduction, 532. 12.2 Terms and Definitions Accuracy Precision, 536. 12.2.2.1 Repeatability, 536. 12.2.2.2 Intermediate Precision Reproducibility, 537. 12.2.2.4 Ruggedness Specificity, 539. 12.2.4 Limit of Detection and Limit of Quantification, 539. 12.2.5 Linearity and Range Robustness, 540. 12.3 System Suitability, 542 12.4 Documentation, 543. 12.4.1 Validation Protocol Test Method Validation Report, 545. 12.5 Validation for Different Pharmaceutical-Method...
tailieu.vn Xem trực tuyến Tải xuống
17.3.5 Module Substitution Put It Back, 821. 17.4 Common Symptoms of HPLC Problems Leaks, 822. 17.4.1.1 Pre-pump Leaks Pump Leaks, 823. 17.4.1.3 High-Pressure Leaks Autosampler Leaks Column Leaks Detector Leaks Abnormal Pressure, 830. 17.4.2.1 Pressure Too High Pressure Too Low Pressure Too Variable Variation in Retention Time, 833. 17.4.3.1 Flow-Rate Problems Column-Size Problems Mobile-Phase Problems Stationary-Phase Problems Temperature Problems Retention-Problem....
tailieu.vn Xem trực tuyến Tải xuống
Figure 2.16a AU absorbance units (UV detection). Equation (9.4) B column hydrogen-bond basicity. CEC capillary electrochromatography CCC countercurrent chromatography CLND chemiluminescent nitrogen detector C m solute concentration in mobile phase CMPA chiral mobile-phase additive. Equation (2.19) DMSO dimethylsulfoxide. F opt optimum mobile-phase flow rate (mL/min) (Section 2.4.1) F s column-comparison function. Equation (6.3) G gradient compression factor. Equation (9.15a) H...
tailieu.vn Xem trực tuyến Tải xuống
Figure 1.4 Recent examples of HPLC capability. (a) Fast separation of six proteins, using gra- dient elution with a 150 × 4.6-mm column packed with 1.5-μm-diameter pellicular particles [5]. (b) initial separation of peptides and proteins from human fetal fibroblast cell by gradi- ent cation-exchange chromatography. (c) further separation of fraction 7 (collected between 24–28 min) on a second column...
tailieu.vn Xem trực tuyến Tải xuống
Zlatkis, eds., 75 years of Chromatography—A Historical Dialog, Elsevier, Amsterdam, 1979.. Gehrke, ed., Chromatography—A Century of Discovery Elsevier, Amsterdam, 2001.. 81), Dekker, New York, 1999.. BASIC CONCEPTS AND THE CONTROL OF SEPARATION. 2.3.2 Role of Separation Conditions and Sample Composition, 28 2.4 PEAK WIDTH AND THE COLUMN PLATE NUMBER N, 35. 2.5.3 Optimizing the Column Plate Number N, 61 2.5.4...
tailieu.vn Xem trực tuyến Tải xuống
where K = (C s /C m ) is the equilibrium constant for Equation (2.2), and = (V s /V m ) is the phase ratio—the ratio of stationary and mobile-phase volumes within the column. values of k can help us interpret and improve the quality of a separation. A solute molecule must be present in either the mobile or...
tailieu.vn Xem trực tuyến Tải xuống
Figure 2.10 Origin and measurement of peak width. (b) peak 3 of Figure 2.6 as a function of %B, shown with the same time scale for each peak.. Because an ideal chromatographic peak has the shape of a Gaussian curve (Section 2.4.2), peak width is sometimes described in terms of the standard deviation σ of the Gaussian curve, where. (2.9c)...
tailieu.vn Xem trực tuyến Tải xuống
Figure 2.13 Knox equation. (a) Plot of reduced plate height h versus reduced velocity ν with A = 1, B = 2, and C = 0.05. All plots based on Equation (2.17) with A = 1, B = 2, and C = 0.05.. Column conditions can be defined as column length and diameter, particle size, and flow rate. Together these...
tailieu.vn Xem trực tuyến Tải xuống
Figure 2.18 Separation as a function of mobile phase %B. methanol-water mixtures as mobile phase. a shorter run time.. However, the term ‘‘optimized’’ is often used in the literature to indicate a relatively improved or preferred separation rather than an absolute best separation.. We will continue this usage in the present book. Sample retention k in isocratic elution is usually...
tailieu.vn Xem trực tuyến Tải xuống
present, it will be necessary to add a buffer to the mobile phase so as to control its pH. pK a values for sample compounds, if available, can be useful during method development (Chapter 7). The molecular weight of the sample may also affect the choice of separation conditions for initial experiments (Sections . Depending on the equipment that is...
tailieu.vn Xem trực tuyến Tải xuống
Gradient elution refers to a continuous change in the mobile phase during separation, such that the retention of later peaks is continually reduced. An illustration of the power of gradient elution is shown in Figure 2.25c, where all peaks for the sample of Figure 2.25a, b are separated to baseline in a total run time of slightly more than 7...
tailieu.vn Xem trực tuyến Tải xuống
3.2.2 Mobile-Phase Filtration, 91 3.3 MOBILE-PHASE DEGASSING, 92. Today there is less distinction between HPLC systems than in the past, and it can be safely said that there are no ‘‘bad’’ HPLC systems currently on the market. Users in the past often would select specific equipment modules from different vendors and, in a mix-and-match approach, would design their own ‘‘ideal’’...