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Metastatic colorectal cancer


Tìm thấy 13+ kết quả cho từ khóa "Metastatic colorectal cancer"

REMARRY and PURSUIT trials: Liquid biopsyguided rechallenge with anti-epidermal growth factor receptor (EGFR) therapy with panitumumab plus irinotecan for patients with plasma RAS wild-type metastatic colorectal cancer

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Plasma ctDNA RAS mutation analysis for the diagnosis and treatment monitoring of metastatic colorectal cancer patients. https://doi.org/10.1093/annonc/mdx125.. Grasselli J, Elez E, Caratù G, Matito J, Santos C, Macarulla T, et al.. Concordance of blood- and tumor-based detection of RAS mutations to guide anti-EGFR therapy in metastatic colorectal cancer. https://doi.org/10.1093/annonc/mdx112..

MONARCC: A randomised phase II study of panitumumab monotherapy and panitumumab plus 5-fluorouracil as firstline therapy for RAS and BRAF wildtype metastatic colorectal cancer: A study by the Australasian Gastrointestinal Trials Group (AGITG)

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Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Kopetz S, Grothey A, Yaeger R, Van Cutsem E, Desai J, Yoshino T, et al.. Encorafenib, Binimetinib, and Cetuximab in BRAF V600E – mutated colorectal Cancer. KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.

Association of emergence of new mutations in circulating tumuor DNA during chemotherapy with clinical outcome in metastatic colorectal cancer

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In this study, by analysis of somatic mutations with a panel covering 1021 genes using the NGS method, we ex- plored the potential association of the detection of new mu- tations in ctDNA during chemotherapy with poor prognosis in the patients with metastatic colorectal cancer..

Second-line chemotherapy after early disease progression during first-line chemotherapy containing bevacizumab for patients with metastatic colorectal cancer

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Keywords: Metastatic colorectal cancer, Bevacizumab continuation beyond progression, Early disease progression, Second-line chemotherapy. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material.

HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer

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Goldberg RM, Rothenberg ML, Van Cutsem E, Benson AB, 3rd, Blanke CD, Diasio RB, Grothey A, Lenz HJ, Meropol NJ, Ramanathan RK et al : The continuum of care: a paradigm for the management of metastatic colorectal cancer. Zacharakis M, Xynos ID, Lazaris A, Smaro T, Kosmas C, Dokou A, Felekouras E, Antoniou E, Polyzos A, Sarantonis J et al: Predictors of survival in stage IV metastatic colorectal cancer. Genetic alterations in colorectal cancer.

The implementation of colorectal cancer screening interventions in low-and middleincome countries: A scoping review

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Burden of colorectal cancer in central and South America. https://doi.org/10.1016/j.canep . Colorectal cancer in Mexico: should a middle income country invest in screening or in treatment. Latin American Expert Summit for Metastatic Colorectal Cancer. Improving outcomes in the treatment and management of metastatic colorectal cancer in Latin America. Differences in colorectal cancer surveillance epidemiology and screening. Colorectal cancer in Russia.

Randomized phase II study of SOX+B-mab versus SOX+C-mab in patients with previously untreated recurrent advanced colorectal cancer with wild-type KRAS (MCSGO-1107 study)

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Exploring the effect of primary tumor sidedness on therapeutic efficacy across treatment lines in patients with metastatic colorectal cancer:. https://doi.org/10.1093/annonc/mdx738.. https://doi.org/10.1093/a nnonc/mdm607.. https://doi.org/10.1056/NEJMoa1305275.. metastatic colorectal cancer. Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO):. https://doi.org/10.1016/S .

Colorectal cancer survival among Ministry of National Guard-Health Affairs (MNG-HA) population 2009–2017: Retrospective study

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Decrease in incidence of colorectal cancer among individuals 50 years or older after recommendations for population-based screening. https://doi.org/10.1016/j.cgh . Colorectal cancer in the Kingdom of Saudi Arabia:. org/10.7314/APJCP . Primary tumor resection in patients with incurable localized or metastatic colorectal cancer: a systematic review and meta-analysis. https://doi.org/10.1007/s .

Factors associated with emergency-onset diagnosis, time to treatment and type of treatment in colorectal cancer patients in Norway

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Rectal cancer patients living in Southern and Eastern Norway, experienced a 5.9-day (95%CI longer waiting time to radiotherapy than the national median.. 0.001) among colorectal cancer patients. The odds of receiving surgery was lower for metastatic colorectal cancer patients (OR CI . In addition, male and married colon cancer patients experienced a 30% (OR CI and 39% (OR CI increased odds of SACT (Supplementary Table 5).

Metastatic colo-rectal cancer: Real life experience from an Indian tertiary care center

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Colorectal cancer (CRC) is important cause of cancer re- lated morbidity and mortality. No established screening colorectal cancer programme exist. This is the first study from Indian sub-continent highlighting the treatment outcome of metastatic colorectal cancer from a tertiary care cancer centre..

Chapter 087. Gastrointestinal Tract Cancer (Part 17)

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Andre T et al: Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colorectal cancer. Compton C et al: American Joint Committee on Cancer Prognostic Factors Consensus Conference. Cunningham D et al: Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. DeGramont A et al: Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer.

Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P40

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Hurwitz HI, Fehrenbacher L, Hainsworth JD et al (2005) Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer. Simkens L, Tol J, Koopman M et al (2008) Current questions in the treatment of advanced colorectal cancer: the CAIRO studies of the Dutch Colorectal Cancer Group.

Improved Outcomes in Colon and Rectal Surgery part 32

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A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. Andre T, Boni C, Mounedji-Boudiaf L et al. Saltz LB, Cox JV, Blanke C et al. Giantonio BJ, Levy DE, O’Dwyer PJ et al. Giantonio BJ, Catalano PJ, Meropol NJ et al. Bevacizumab in combination with chemother- apy: first-line treatment of patients with metastatic colorec- tal cancer. Saltz LB, Lenz HJ, Kindler HL et al.

Artificial intelligence for pre-operative lymph node staging in colorectal cancer: A systematic review and meta-analysis

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Lymph node evaluation in colorectal cancer patients: a population- based study. https://doi.org/10.1 093/jnci/dji020.. https://doi.org/10.6004/jnccn.2018.0021.. https://doi.org/10.. https://doi.org/10.1016/j.crad . https://doi.org/10.1111/codi.14794.. https://doi.org/10.3348/kjr . https://doi.org/10.1097/DCR . https://doi.org/10.5152/dir . A deep learning nomogram kit for predicting metastatic lymph nodes in rectal cancer.. https://doi.org/10.1002/cam4.3490..

Gut microbiome and its role in colorectal cancer

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The Impact of the Gut Microbiome on Colorectal Cancer. Significance of the gut microbiome in multistep colorectal carcinogenesis. Disruption of the gut ecosystem by antibiotics

Mapping psychosocial interventions in familial colorectal cancer: A rapid systematic review

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Predictive testing for hereditary nonpolyposis colorectal cancer:. Genetic counseling outcomes: perceived risk and distress after coun- seling for hereditary colorectal cancer. Codori AM, Zawacki KL, Petersen GM, Miglioretti DL, Bacon JA, Trimbath JD, et al. Genetic testing for hereditary colorectal cancer in children:. Assessment of education and counselling offered by a familial colorectal cancer clinic.

Polygenic risk prediction models for colorectal cancer: A systematic review

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Screen- ing for colorectal cancer: a systematic review and meta-analysis. Clin Colorectal Cancer. Risk predic- tion models for colorectal cancer: a systematic review. Risk prediction models for colorectal cancer incorporating common genetic variants: a systematic review. Colorectal cancer. Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish family-cancer database.

Upregulated NLGN1 predicts poor survival in colorectal cancer

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Colorectal cancer (CRC) has seen a obvious increase in the annual global incidence rate and is the third most common cancer worldwide [1]. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.. The role of NLGN1 in cancer is largely unknown.

A case-control study of Dietary Approaches to Stop Hypertension (DASH) diets, colorectal cancer and adenomas among Iranian population

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Colorectal cancer family history in first degree relatives (yes). DASH score components control Colorectal cancer Adenomas p -value*. Table 4 OR and 95% confidence interval for risk of colorectal cancer, adenoma and colorectal cancer plus adenoma based on quartile of energy-adjusted DASH score. Colorectal cancer Women.