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Molecular subtype


Tìm thấy 11+ kết quả cho từ khóa "Molecular subtype"

Association of body composition with odds of breast cancer by molecular subtype: Analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study

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Association of body composition with odds of breast cancer by molecular subtype:. analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study. Background: The association between obesity and breast cancer (BC) has been extensively studied among US, European and Asian study populations, with often conflicting evidence. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/..

Discovering lncRNA mediated sponge interactions in breast cancer molecular subtypes

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Steps B-F are conducted for each breast cancer subtype separately. c Venn diagram of ceRNA interactions discovered in each of the breast cancer molecular subtype. out to discover subtype-specific breast cancer ceRNA interactions where lncRNAs can act as miRNA sponges to reduce the amount of miRNAs available to target mRNAs.. 1a and identify ceRNAs specific to four molecular subtypes of breast cancer: Luminal A, Luminal B, HER2, and Basal..

Online database for brain cancer-implicated genes: Exploring the subtype-specific mechanisms of brain cancer

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Although many existing clin- ical and histological methods identify brain cancer sub- types, molecular subtype information can independently and reliably confirm or refute those identifications, thus providing more accurate diagnostic evidence.. Although thousands of published articles have focus on brain cancer, a literature-based effort that scrutinizes both the common and unique genetic information of each brain cancer subtype does not exist.

Molecular and cellular characterization of two patient-derived ductal carcinoma in situ (DCIS) cell lines, ETCC-006 and ETCC010

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Before comparing the molecular details of those cell lines, we first examined overall cell morphology by comparing ETCC-006 and. Moreover, ETCC-006 cells were phenotypically striking because of their apparent flatness when visualized under the microscope. The difference in morphology between ETCC-006 and ETCC-010 is interesting since they both have the same genetic background, highlighting tumor heterogeneity within DCIS lesions [31].. Molecular subtype of DCIS cell lines.

Morphologic and molecular correlates of EZH2 as a predictor of platinum resistance in high-grade ovarian serous carcinoma

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Neither mRNA nor protein EZH2 expression was associated with overall survival (mRNA P = 0.44, protein P = 0.57) or HGSOC molecular subtype-specific survival.. file 1) with EZH2 expression levels in the RTT logistic model (see Methods). Of the modifier genes, 72% (n = 118) negatively modified or decreased the prognostic significance of EZH2, including arginine methyltransferase CARM1, and 28% positively modified (increased) the prognostic significance of EZH2 such as lncRNA MALAT1 (Fig..

Precision treatment exploration of breast cancer based on heterogeneity analysis of lncRNAs at the single-cell level

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PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer. Breast Cancer Res Treat. https://doi.org/10.1007/. Practical Approach to Triple-Negative Breast Cancer. Presenting Features of Breast Cancer Differ by Molecular Subtype. Breast cancer: basics, screening, diagnostics and treatment.. Triple negative breast cancer: looking for the missing link between biology and treatments. https://doi.org/10.18632/.

A stemness-based eleven-gene signature correlates with the clinical outcome of hepatocellular carcinoma

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In this study, we identified the molecular subtypes of HCC based on the expression of stemness-related genes (SRGs), which provided a new molecular subtype classification of HCC, and further studied the genomic background of the molecular char- acteristics of HCC.

TFEB, SIRT1, CARM1, Beclin-1 expression and PITX2 methylation in breast cancer chemoresistance: A retrospective study

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Differences in autophagy-related activity by molecular subtype in triple-negative breast cancer. Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel. PITX2 DNA-methylation predicts response to anthracycline-based adjuvant chemotherapy in triple-negative breast cancer patients

The impact of young age (

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Breast cancer recurrence according to molecular subtype. Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer upon five years of endocrine therapy.. Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies.

Clinical verification of body mass index and tumor immune response in patients with breast cancer receiving preoperative chemotherapy

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Prognostic role of body mass index is different according to menopausal status and tumor subtype in breast cancer patients. Body mass index and survival after breast cancer diagnosis in Japanese women.. Breast cancer risk factors, survival and recurrence, and tumor molecular subtype:. Breast Cancer Res. Body mass index, waist- to-hip ratio and late outcomes: a report from the Shanghai breast Cancer survival study.

Refinement of breast cancer molecular classification by miRNA expression profiles

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Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res. Fan C, Oh DS, Wessels L, Weigelt B, Nuyten DS, Nobel AB, et al.. Concordance among gene-expression-based predictors for breast cancer. Haibe-Kains B, Desmedt C, Piette F, Buyse M, Cardoso F, Van't Veer L, et al.. Comparison of prognostic gene expression signatures for breast cancer.. Dowsett M, Sestak I, Lopez-Knowles E, Sidhu K, Dunbier AK, Cowens JW, et al.

Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 5)

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A notable example of the effect of host receptors on the pathogenesis of infection comes from comparative binding studies of avian influenza A virus subtype H5N1 and influenza A virus strains expressing hemagglutinin subtype H1. The H1-subtype strains, which tend to be highly pathogenic and transmissible from human to human, bind to a receptor composed of two sugar molecules: sialic acid linked α-2-6 to galactose. This receptor is. highly expressed in the airway epithelium.

Subtype-Independent ANP32E Reduction During Breast Cancer Progression in Accordance with Chromatin Relaxation

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Methods: We applied a series of unsupervised computational methods to identify chromatin and molecular differ- ences associated with discrete physiologies across human breast cancer tumors.. Conclusions: Our results indicate that ANP32E may function through chromatin state regulation to control breast cancer differentiation and tumor plasticity.

TÍNH ĐA TYPE, ĐA SUBTYPE CỦA VIRUS GÂY BỆNH LỞ MỒM LONG MÓNG , YẾU TỐ PHỨC TẠP

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Các chủng virus trên đều khác nhau về mặt kháng nguyên nên khi phòng bệnh bằng vaccin cần xác định được type, subtype của virus phù hợp với loại virus đang lưu hành thì việc tiêm phòng mới có kết quả..

KHẢO SÁT SỰ LƯU HÀNH VÀ BƯỚC ĐẦU GIẢI TRÌNH TỰ GENE CỦA VIRUS CÚM GIA CẦM SUBTYPE H5N1 TẠI TỈNH CÀ MAU VÀ SÓC TRĂNG

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Ở tỉnh Sóc Trăng có sự lưu hành của virus cúm gia cầm subtype H5 với tỷ lệ 1,67. Ở tỉnh Cà Mau không phát hiện sự lưu hành của virus cúm gia cầm subtype H5N1.

Correlation between vascular endothelial growth factor pathway and immune microenvironment in head and neck squamous cell carcinoma

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(D-F) Functional enrichment analysis revealed that immune-related GO terms ranked top in cellular components, biological process, and biological process molecular func- tions in HPV-positive HNSCC.. GSEA Molecular Signatures Database (https://www.gsea- msigdb.org/gsea/index.jsp). STRING database (https://string-db.org). ESTIMA TE algorithm, (https://bioinformatics.mdanderson.org/estimate/index.html)..

Molecular Physics

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Structure of the Spectra of Diatomic Molecules. 4.3 Orientation of the molecular axis (Z axis) in the labora- tory frame X , Y , Z. of the nuclear frame- work,. 4.2 Structure of the Spectra of Diatomic Molecules I 131. of the vibrational function ?,bVib(R. the vibrational part of the matrix element Eq. 4.2 Structure of the Spectra of Diatomic Molecules I 133.

Introduction to molecular biology

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Galperin, The Molecular Biology Database Collection: 2005 update, NAR – www.bioinfo.no/links www.bioinfo.no/links , list of useful biological links , list of useful biological links