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Protein kinase C

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Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA)

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Additional overactive kinases, which have not yet been investigated in detail in the context of BCR-ABL1, included CDC2-Like Kinase 1/2 (CLK1/2), Glycogen Synthase Kinase 3B (GSK3B), Monopolar Spindle 1 kinase (MPS1), also known as TTK Protein Dual Specificity Protein Kinase, and Protein Kinase C Beta (PRKCB)..

Sevofurane and isofurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas

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Yu J, Ogawa K, Tokinaga Y, et al. triphosphate–stimulated, Rho/Rho-kinase–mediated contraction of isolated rat aortic smooth muscle. Yu J, Tokinaga Y, Ogawa K, et al. induced, protein kinase C–mediated but not Ca 2+ -elicited contraction of rat aortic smooth muscle. Qi F, Ogawa K, Tokinaga Y, et al. Yang S, Wu Q, Huang S, et al. Miyamoto Y, Feng GG, Satomi S, et al. Fujii K, Ogawa K, Tokinaga Y, et al.

Metabolic and transcriptome responses of RNAi-mediated AMPKα knockdown in Tribolium castaneum

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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Roles of the Snf1/Rkin1/AMP-activated protein kinase family in the response to environmental and nutritional stress. Complexes between the LKB1 tumor suppressor, STRAD α / β and MO25 α / β are upstream kinases in the AMP-activated protein kinase cascade. Calmodulin-dependent protein kinase kinase- β is an alternative upstream kinase for AMP-activated protein kinase.

Biochemistry, 4th Edition P107

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One of these, protein kinase C, is de- scribed in Section 32.5.

Genome-wide characterization and expression profiling of MAPK cascade genes in Salvia miltiorrhiza reveals the function of SmMAPK3 and SmMAPK1 in secondary metabolism

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Mitogenactivated protein kinase cascades in plant: a new nomenclature. The tomato mitogen-activated protein kinase SlMPK1 is as a negative regulator of the high-temperature stress response. In Silico analysis reveals 75 members of mitogen-activated protein kinase kinase kinase gene family in Rice. Rice mitogen-activated protein kinase gene family and its role in biotic and abiotic stress response.

Biochemistry, 4th Edition P108

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A role for protein kinase C in cellular growth and division is demon- strated through its strong activation by phorbol esters (Figure 32.37). The phorbol esters mimic DAG, bind to the regulatory pseudosubstrate domain of the enzyme, and activate protein kinase C..

Chức năng của miR-146b-5p trong Chondrocyte

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HCMCOUJS-Kỹ thuật và Công nghệ STT Genes Tên gene 1 RAC1 Ras-related C3 botulinum toxin substrate 1 2 TRAF6 TNF receptor-associated factor 6 Adhesion signalling 1 LPP Lipoma-preferred partner 2 CCN4 CCN family member 4 3 TLN Talin-2 3 NPTN Neuroplastin Apoptosis pathway 1 CASP7 Caspase-7 2 PRKCE Protein kinase C epsilon type Cadherin signalling pathway 1 FZD1 Frizzled-1 2 PTPN1 Tyrosine-protein phosphatase non-receptor type 1 3 FZD3 Frizzled-3 4 FZD9 Frizzled-9 5 YES1 Tyrosine-protein kinase Yes

Biochemistry, 4th Edition P72

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Four protein kinases are involved in phosphorylation of glycogen synthase: casein kinase, AMP-dependent protein kinase, protein kinase A, and glycogen synthase kinase 3 (GSK3).. The action of PP1 inactivates glycogen phosphorylase and activates glycogen synthase.. Glycogen synthase I (active). Glycogen synthase D. Glycogen synthesis. FIGURE 22.17 (a) Binding of insulin to plasma mem- brane receptors in the liver and muscles triggers protein kinase cascades that stimulate glycogen synthesis..

Transcriptome sequencing and whole genome expression profiling of hexaploid sweetpotato under salt stress

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Protein kinases (PKs) differentially expressed under salt stress. SNF1-related protein kinase was up-regulated during 6 h (7 unigenes) and 48 h (4 unigenes) of salt stress expressed in two forms including SNF1-related protein kinase cata- lytic subunit alpha KIN10-like and SNF1-related protein kinase regulatory subunit gamma-1. One unigene aligned to Phosphatidylinositol 4-phosphate 5-kinase was up- regulated during 6 and 48 h after salt stress.

Transcriptomic insights into the effects of CytCo, a novel nematotoxic protein, on the pine wood nematode Bursaphelenchus xylophilus

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Gene Ontology enrichment analysis showed that the CytCo treatment substantially affected DEGs involved in muscle contraction, lipid localization, and the mitogen-activated protein kinase cascade.

Genome-wide survey and expression analysis of calcium-dependent protein kinase (CDPK) in grass Brachypodium distachyon

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Typical CDPK gene family mem- bers were composed of four conserved domains, includ- ing a variable N-terminal domain, a protein kinase domain, an auto-inhibitory domain and a C-terminal regulatory calmodulin-like domain [6]. The protein kinase domain contains a catalytic Ser/Thr protein kinase domain with a ATP binding site and is adjacent to the auto-inhibitory domain, acting as a pseudosubstrate combined with kinase domain to maintain CDPK inactive [18, 19].

Genome-wide investigation of calciumdependent protein kinase gene family in pineapple: Evolution and expression profiles during development and stress

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CPK: Calcium-dependent protein kinase. Evidence for differing roles for each lobe of the calmodulin-like domain in a calcium-dependent protein kinase. The Arabidopsis calcium-dependent protein kinase gene family. The evolutionary history and diverse physiological roles of the grapevine calcium-dependent protein kinase gene family. Membrane-associated protein kinase activities in the developing mesocarp of grape berry.

Characterization and tissue-specific as well as heat-stress expression analysis of CBL-interacting protein kinase genes in Dimocarpus longan Lour

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CBL-interacting protein kinase, the specific target protein kinase of CBL, is a unique family of protein kinases with serine–threonine kinase activity that is found in plants (Luan et al., 2002). The lengths of DlCIPKs from D. In maize, the longest and shortest CIPKs were about 400 and 500 AA, respectively (Wang et al., 2007;. Zhao et al., 2009).

Genome-wide survey of sucrose nonfermenting 1-related protein kinase 2 in Rosaceae and expression analysis of PbrSnRK2 in response to ABA stress

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Background: The members of the sucrose non-fermenting 1-related protein kinase 2 (SnRK2) family are specific serine/threonine protein kinases in plants that play important roles in stress signal transduction and adaptation.. Results: A genome-wide survey and analysis of the genes encoding members of the SnRK2 family were performed in pear ( Pyrus bretschneideri ) and seven other Rosaceae species.

Genome-wide analysis of proline-rich extension-like receptor protein kinase (PERK) in Brassica rapa and its association with the pollen development

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Genome-wide analysis of proline-rich extension-like receptor protein kinase. Background: Proline-rich extension-like receptor protein kinases (PERKs) are an important class of receptor kinases located in the plasma membrane, most of which play a vital role in pollen development.. The biophysical properties of the BrPERKs were investigated.

The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

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Some woodland strawberry PK genes have been characterized and shown to be involved in abi- otic and biotic stress responses including MAPKs [16], AMP-activated protein kinase (AMPK) [17], leucine-rich repeat receptor-like protein kinase (LRR-RLK) [18], and calcium-dependent protein kinase (CDPK) [19].. We determined the structure and chromosomal distribution of the PK genes, as well as made predictions on the subcellular localization of the putative PK proteins.

Keratin 14 is a novel interaction partner of keratinocyte differentiation regulator: receptor-interacting protein kinase 4

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HaCaT cells were transfected with Flag-RIPK4 and GST-KRT14 together (C).. lot analysis showed that RIPK4 KO had approximately 20% of RIPK4 protein compared to the parental cell line, which indicates that deletion destabilizes the protein (Sup- plementary Figure 1B)..

A leucine-rich repeat-receptor-like kinase gene SbER2–1 from sorghum (Sorghum bicolor L.) confers drought tolerance in maize

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Overexpression of the leucine-rich receptor-like kinase gene LRK2 increases drought tolerance and tiller number in rice. threonine protein kinases in signaling: analysis of the erecta receptor-like kinase of Arabidopsis thaliana [review]. structure and macromolecular composition of the seed coat of the musaceae

Comparative transcriptome analysis of soybean response to bean pyralid larvae

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Glyma.08G010400.1 SAUR family protein . Glyma.06G006500.1 SAUR family protein . Glyma.04G006600.1 SAUR family protein . Glyma.06G282000.1 SAUR family protein. Glyma.05G220200.4 Protein kinase 8.92. Glyma.14G116000.7 Protein kinase 7.77. Glyma.07G253900.1 Protein kinase A 7.99. Glyma.17G029200.1 Protein kinase A – 8.43. Glyma.18G242700.2 Protein kinase A. Glyma.17G029200.1 Protein kinase A. Glyma.18G054100.1 Serine/threonine-protein kinase WNK .

The effect of R547, a cyclin-dependent kinase inhibitor, on hepatocellular carcinoma cell death

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Cyclin-dependent kinases (CDKs) are members of the serine/threonine protein kinase family.. They have very important roles in cell cycle regulation and transcription (Sanchez-Martinez et al., 2015). At the G1 phase of the cell cycle, the CDK4/cyclin D and CDK6/. cyclin D complexes regulate the termination of the cycle Abstract: Hepatocellular carcinoma (HCC) is the third main cause of cancer-related death. Cyclin-dependent kinases (CDKs) and their cyclin partners regulate the cell cycle.