Có 60+ tài liệu thuộc chủ đề "cơ chế thần kinh"
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Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S et al (2000) Inflammation and Alzheimer’s disease. Andjelkovic AV, Pachter J (1998) Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease. Angstwurm K, Hanisch U-K, Gassemi T, Bille MB, Prinz M, Dirnagl U, Kettenmann H,...
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et al., 1988). Winter et al., 2008).. Interestingly, 99% of blood serotonin is contained in platelets (Anderson et al., 1987) and studies have shown that there is an approximate 50%. controls (McBride et al., 1998). Hypotheses for increased serotonin include increased synthesis of serotonin by tryptophan hydroxylase (TPH1), increased uptake of serotonin into platelets via serotonin transporters (5-HTT), diminished release...
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Absence of association between a polymor- phic GGC repeat in the 5 untranslated region of the reelin gene and autism. Lam KS, Aman MG, Arnold LE (2006) Neurochemical correlates of autistic disorder: a review of the literature. Laprade N, Soghomonian JJ (1999) Gene expression of the GAD67 and GAD65 isoforms of glu- tamate decarboxylase is differently altered in subpopulations of...
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First, the ESE Finder (http://rulai.cshl.org/ESE/) calculates the similarity of a given nucleotide sequence to the consensus sequences of four splicing trans-factors, SF2/ASF, SC35, SRp40, and SRp55 (Cartegni et al., 2003. Smith et al., 2006).. Second, the RESCUE-ESE Web server (http://genes.mit.edu/burgelab/rescue-ese/) shows the similarity of a given sequence to ESE elements of unidentified splicing trans-factors (Fairbrother et al., 2002). The same...
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Nucleic Acids Res Smith PJ, Zhang C, Wang J, Chew SL, Zhang MQ et al (2006) An increased specificity score. Szabo A, Dalmau J, Manley G, Rosenfeld M, Wong E et al (1991) HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal. Takahara K, Schwarze U, Imamura Y, Hoffman GG, Toriello H et al...
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activation (Guo et al., 1996. Ortiz et al., 2008). Ganong et al., 1983;. Horvath et al., 1994. Kalso et al., 1991. Kuraishi et al., 1985. Reimann et al., 1999).. Khasar et al., 1999. Moon et al., 1999). Dopamine (4-(2-aminoethyl) benzene-1,2-diol) constitutes about 80% of the cat- echolamine content in the brain (Pivonello et al., 2007. Vallone et al., 2000).. Carta...
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nociception acting on GlyRs (Pellicer et al., 2007). Both IT and intraperitoneal (IP) administration of taurine relieves nociceptive stimulation effects, and pain stimulus releases taurine in the spinal cord (Hornfeldt et al., 1992. Ishikawa et al., 2000. Serrano et al., 1998. Skilling et al., 1990. Smullin et al., 1990).. Degradation of the essential amino acid tryptophan along the kynurenine pathway...
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NRM, or amygdala generates antinociception in the acute pain test (Reny-Palasse et al., 1989. Webster et al., 1983). Pan et al., 2008. Pinter et al., 2006). Pinter et al., 2006. Sandor et al., 2006). Yu et al., 2004). Than et al., 2000).. Ramaswamy et al., 1985). Vergnano et al., 2008). therefore it may attenuate proinflammatory cytokine-mediated neuropathic pain (Dixit et...
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several brain areas as well (Ballet et al., 1998. Olgiati et al., 1983. Shimada et al., 1989). Xu et al., 2003. Yu et al., 2003). Li et al., 2008. Morton et al., 1991. Santicioli et al., 1993).. Delgado et al., 2003. Narita et al., 1996). Mabuchi et al., 2004. Martin et al., 2003).. Narita et al., 1996. Ohsawa et al.,...
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Yao et al., 2002a).. IL-2 produces analgesic effect in both CNS and PNS (Jiang et al., 2000b. Yao et al., 2002a). Jiang et al., 2000a. Wu et al., 1999b). Wang et al., 1996. Wu et al., 1999b. Yao et al., 2002b. Fiorentino et al., 1991. Hart et al., 1989). Vale et al., 2003). IT or intra-PAG administration of fractalkine to...
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the cannabimimetic effects have largely been attributed to the indirect entourage effect on the endocannabinoid system (Mechoulam et al., 1998). Vasquez et al., 2001).. A profound basal release of PGD2 in the spinal cord has been reported, and peripheral nociceptive stimu- lation and systemic inflammation increases spinal PGD2 biosynthesis (Grill et al., 2008. Willingale et al., 1997). Activation of DP1...
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Thus the specific response of a cell to a ligand will be determined as the sum of many variables, and net effect of different ligands depends upon all of these factors. Not all of the endogenous ligands have been discovered, and even fewer data are available about their interactions, therefore researchers need to continue identifying key cellular and molecular factors...
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Drew GM, Siddall PJ, Duggan AW (2004) Mechanical allodynia following contusion injury of the rat spinal cord is associated with loss of GABAergic inhibition in the dorsal horn. Eur J Pharmacol . Front Biosci Dubois A, Savasta M, Curet O, Scatton B (1986) Autoradiographic distribution of the D1 agonist. [H-3] Skf 38393, in the rat-brain and spinal cord - comparison...
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Kamei J, Hitosugi H, Kawashima N, Misawa M, Kasuya Y (1993b) Antinociceptive effects of intrathecally administered endothelin-1 in mice. Kanjhan R, Housley GD, Burton LD, Christie DL, Kippenberger A, Thorne PR, Luo L, Ryan AF (1999) Distribution of the P2X(2) receptor subunit of the ATP-gated ion channels in the rat central nervous system. Kastin AJ, Stephens E, Ehrensing RH, Fischman...
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Niederberger E, Schmidtko A, Gao W, Kuhlein H, Ehnert C, Geisslinger G (2007) Impaired acute and inflammatory nociception in mice lacking the p50 subunit of NF-kappaB. Nijsen M, Ongenae N, Meulemans A, Coulie B (2005) Divergent role for CRF1 and CRF2 receptors in the modulation of visceral pain. Obara I, Przewlocki R, Przewlocka B (2004) Local peripheral effects of mu-opioid...
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Suarez C, Tornadu IG, Cristina C, Vela J, Iglesias AG, Libertun C, Diaz-Torga G, Becu-Villalobos D (2002) Angiotensin and calcium signaling in the pituitary and hypothalamus. Sugden D (1983) Psychopharmacological effects of melatonin in mouse and rat. Suh HW, Song DK, Choi YS, Kim YH (1996) Effects of intrathecally injected histamine recep- tor antagonists on the antinociception induced by morphine,...
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ing the ventrolateral orbital cortex opioid-induced inhibition of mirror-neuropathic pain in the rat. Zhuo M, Gebhart GF (1990) Spinal cholinergic and monoaminergic receptors mediate descending inhibition from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat. Zubrzycka M, Janecka A (2008) Interactions of galanin with endomorphin-2, vasopressin and oxytocin in nociceptive modulation of the trigemino-hypoglossal reflex in rats....
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Axonal loss is also observed in the demyelinating type 1 CMT (Bjartmar et al., 1999). In addition, there is a reversion of the Na v channel from a mature Na v 1.6 expression to an immature Na v 1.2 isoform and this may limit axonal injury (Craner et al., 2004a, b). During myelin repair, a thinner myelin sheath is produced...
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More details on CGT are in the paragraph related to myelin lipids, below.. These data indicate the importance of both molecules in the initiation of myelination. how- ever, they could also mean that MAG and Fyn act in concert or independently in initiating myelination (Biffiger et al., 2000).. Interestingly, P0 is essential for normal spacing of PNS compact myelin (reviewed...
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domains: MAG is selectively targeted to periaxonal membranes, PLP to compact myelin, CNP to noncompact regions of the myelin internode, and MBP mRNA to oligodendrocyte processes (Trapp et al., 2004). The lack of myelin recovery may be due primarily to deficiency in the genesis of OPCs and in their maturation in the adult CNS (Franklin, 2002. Stangel and Hartung, 2002)...