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Innate immunity


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The Komodo dragon (Varanus komodoensis) genome and identification of innate immunity genes and clusters

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Conclusions: Genes with important roles in host-defense and innate immunity were identified in this newly sequenced Komodo dragon genome, suggesting that these organisms have a robust innate immune system. Importantly, many of the antimicrobial peptide genes were found in gene clusters.

Innate immunity in the simplest animals – placozoans

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Evolution of the lectin-complement pathway and its role in innate immunity. https://doi.org/10.1038/nri800.. https://doi.org/10.1093/bioinformatics/btu031.. https://doi.org/10.1093/bioinformatics/bti125.. https://doi.. https://doi.org/10.1016/. https://doi.org/10.1016/j.dci.. https://doi.org/10.1016/j.fsi..

The draft genome of horseshoe crab Tachypleus tridentatus reveals its evolutionary scenario and well-developed innate immunity

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Innate immunity in the horseshoe crab.. Clotting cascade and defense molecules found in the hemolymph of the horseshoe crab. The secret in the blue blood. Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. In: Proceedings of the Eleventh International Conference on Language Resources and Evaluation (LREC 2018)

RNA-Seq analysis of differentially expressed genes relevant to innate and adaptive immunity in cecropin P1 transgenic rainbow trout (Oncorhynchus mykiss)

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Cecropin B, which was first identified in cecropia moth, Hyalophora cecropia, is one of the antimicrobial peptide (AMP) family member proteins playing an essential role in the innate immunity of insects [2].. Cecropin P1, identified from nema- tode inhabiting in the porcine small intestine, was found to be more potent against Gram-negative bacteria than Gram-positive bacteria [5], and was thus chosen as transgenic target gene in our laboratory for production of transgenic rainbow trout..

Gene expression kinetics of Exaiptasia pallida innate immune response to Vibrio parahaemolyticus infection

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Therefore, com- parative studies of the innate immune response in corals, Hydra, Nematostella, and Exaiptasia have the potential to help us understand how certain aspects of innate immunity evolved and may also point to alter- native paths to activation of well conserved key factors of immunity..

Immune profiles of male giant panda (Ailuropoda melanoleuca) during the breeding season

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Our results suggest that most immune-related genes were up-regulated and more related to innate immune than adaptive immune.. Conclusions: Our results indicated that breeding male giant pandas presented an immunoenhancement in innate immunity, enhanced antigen presentation and processing in cellular immunity compared to non-breeding males.. The humoral immunity of male giant pandas may show a tendency to decrease during the breeding season.

Tiem Chung Mien Dich 2015

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TIÊM CHỦNG BS Đỗ Cao Vân Anh Câu hỏi Miễn dịch: Immunity, bắt nguồn từ Immunitas tiếng La tinh có nghĩa là miễn trừ. là m)t b*c +ĩ ng-i ha ng/0i 1nh, 23 +4ng 5à làm 5i6c 7 89r9l9y, luc9+t9r+hir9, mi;n am n/?c 1nh. @ng là b*c +ĩ 2Au tiBn nghiBn cCu 5à +D dEng 5ắc Fin 2G Hhng ch4ng b6nh 2Ju mKa. Miễn dịch Bẩm sinh ( Tự nhiên) (innate immunity. àng rà 5Jt lN àng rà hóa hOc àng rà +inh hOc(hàng rà tế bà. àng rà thG chPt QiBm hRng 2Sc hi6u hu !ư"c (adaptive immunity

Lesson Some points updated on myocarditis

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Exposure of intracellular antigens (cardiac myosin) and an innate immune response comprised of altered regulatory T cell function, NK cells, interferon gamma, nitric oxide…. Heart specific immune response characterized by antibodies to pathogen, host cardiac proteins and autoreactive T cells.. Immune Pathogenesis of Chronic DCM. Acute Myocarditis. Dilated Cardiomyopathy. Innate Immunity/TLRs Anti-viral response. Pathogenesis of DCM After Enteroviral Infection. Coxsackie B virus.

Encyclopedia Of Animal Science - I

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The cells of the immune system and their responses to infection are obviously complex, but can be partitioned into two separate but interacting components those that provide innate immunity and those that provide acquired (or adaptive) immunity (Fig. The component of the immune system that protects the host animal but does not distinguish one pathogen from another provides innate immunity.

Genomic architecture of haddock (Melanogrammus aeglefinus) shows expansions of innate immune genes and short tandem repeats

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A detailed characterization of the TLR gene repertoire – membrane- bound receptors belonging to the pattern recognition re- ceptors (PRRs) family and an important component of the innate immunity [14. An extreme expansion of MHCI genes – with more than 100 copies in some species – is another peculi- arity of the immune system that Atlantic cod shares with many of the other gadiform species [11]. compensating for the loss of the MHCII genes [17].

Chapter 132. Infections Caused by Listeria monocytogenes (Part 2)

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Mice that survive sublethal infection clear the infection within a week, with consequent sterile immunity. Knockout mice have been used to show that interferon γand tumor necrosis factor (TNF) are essential in controlling infection. While innate immunity is sufficient to control infection, the acquired. immune response is required for sterile immunity. Immunity is cell-mediated;. The bacteria grow and spread from cell to cell.

Identification and analysis of long noncoding RNAs and mRNAs in chicken macrophages infected with avian infectious bronchitis coronavirus

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We conducted in vitro studies to assess the changes in the expression of genes related to innate immunity in IBV-infected HD11 cells using high- throughput sequencing. We stud- ied the lncRNA-related immune response in IBV- infected HD11 cells.

Transcriptomic analysis of sea cucumber (Holothuria leucospilota) coelomocytes revealed the echinoderm cytokine response during immune challenge

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The innate immunity of sea cucumber includes multiple immune- related factors, such as, antimicrobial peptides (e.g. In sea cucumber, the cellular immunity is executed by coelomocytes, and the humoral immunity is based on a variety of macromolecules in the coelomic cavity that secreted by coelomocytes [10–12].

Sử dụng thức ăn bổ sung chất chiết lá lựu (Punica granatum) phòng bệnh hoại tử gan tụy cấp tính trên tôm thẻ chân trắng (Litopenaeus vannamei)

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Results showed that (i) dietary supplementation of disease in whiteleg shrimp pomegranate extract could increase the growth rate and innate immunity of (Litopenaeus vannamei) whiteleg shrimp. (ii) dietary supplementation of 2% pomegranate extract could significantly increase survival rate of whiteleg shrimp after being challenged to Vibrio parahaemolyticus. The obtained results suggested potential Từ khóa: applications of the pomegranate extract in commercial shrimp farming.

A transcriptomic snapshot of early molecular communication between Pasteuria penetrans and Meloidogyne incognita

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Several of the differentially expressed transcripts were putatively involved in nematode innate immunity, signaling, stress responses, endospore attachment process and post-attachment behavioral modification of the juveniles. We found that adhesion of Pasteuria endospores to the cuticle induced a down- regulated protein response in the nematode.

Integrated analysis of lncRNA and mRNA in liver of Megalobrama amblycephala post Aeromonas hydrophila infection

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For example, lncRNAs are in- volved in the host response to viral infection and innate immunity during SARS-CoV infection in mouse [18]. Additionally, it’s shown that lncRNAs are specific- ally involved in the mammalian cell response toward bacterial infections [11].. Be- sides, antisense lncRNA PU.1 is found to be involved in the adaptive immunity of zebrafish [22].

Morphological characterization of hemocyte types in some species belonging to Tettigoniidae and Pamphagidae (Insecta: Orthoptera)

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Insect immunity: evolutionary roots of the mammalian innate immune system. Ultrastructural and functional characterization of circulating hemocytes from Galleria mellonella larva: cell types and their role in the innate immunity

ĐẠI CƯƠNG VỀ MIỄN DỊCH HỌC (Kỳ 2)

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Các cơ chế đề kháng của cơ thể bao gồm miễn dịch bẩm sinh (innate immunity) có vai trò bảo vệ cơ thể ngay lập tức (ngay khi mới sinh ra cũng như ngay khi nhiễm trùng mới xẩy ra) chống lại nhiễm trùng và miễn dịch thích ứng (adaptive immunity) là trạng thái miễn dịch xuất hiện chậm hơn và tham gia vào bảo vệ cơ thể chống nhiễm trùng ở giai đoạn muộn hơn nhưng hiệu quả hơn (Hình 1.3)..

Transcriptome analysis reveals modulation of the STAT family in PEDV-infected IPEC-J2 cells

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As a non-negligible component of the JAK-STAT signaling pathway, STAT factors play an indispensable role in innate immunity to viral infection. Each member of the STAT family can be activated by multiple cytokines and their associated JAKs.