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Chủ đề : Immune response


Có 20+ tài liệu thuộc chủ đề "Immune response"

Multi-species transcriptome meta-analysis of the response to retinoic acid in vertebrates and comparative analysis of the effects of retinol and retinoic acid on gene expression in LMH cells

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Multi-species transcriptome meta-analysis of the response to retinoic acid in. vertebrates and comparative analysis of the effects of retinol and retinoic acid on gene expression in LMH cells. BMC Genomics https://doi.org/10.1186/s . A meta-analysis of the effects of retinoic acid on gene expression in different vertebrate tissues. The results of each respective differential expression analysis from chicken hepatocellular carcinoma (LMH)...

Immune-related genes of the larval Holotrichia parallela in response to entomopathogenic nematodes Heterorhabditis beicherriana LF

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Immune-related genes of the larval Holotrichia parallela in response to entomopathogenic nematodes. parallela PGRP-SC1, PPAE-I and GST are involved in the immune responses to resist H. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in...

Dense time-course gene expression profiling of the Drosophila melanogaster innate immune response

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profiling of the Drosophila melanogaster innate immune response. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. BMC Genomics https://doi.org/10.1186/s . In this study, we performed a dense time-course RNA- seq analysis of the Drosophila transcriptional response to commercial E. coli-derived crude lipopolysaccharide (LPS), which activates the Imd pathway [21], to better understand the dynamics of activation and resolution of...

Transcriptome profiling of immune response to Yersinia ruckeri in spleen of rainbow trout (Oncorhynchus mykiss)

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response to Yersinia ruckeri in spleen of rainbow trout ( Oncorhynchus mykiss. Background: Yersinia ruckeri is a pathogen that can cause enteric redmouth disease in salmonid species, damaging global production of economically important fish including rainbow trout (Oncorhynchus mykiss). Herein, we conducted the transcriptomic profiling of spleen samples from rainbow trout at 24 h post-Y. ruckeri infection via RNA-seq in...

Exposure to hypoxia causes stress erythropoiesis and downregulates immune response genes in spleen of mice

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Clustering analysis of the. The spleen is also a reservoir of red blood cells (RBC), and can store 15–25% of the total RBC volume [3, 4]. In response to exercise, apnea, or simu- lated altitude, stored RBCs are ejected and the volume of the spleen decreases in humans [8, 9]. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. The...

Transcriptome analysis reveals modulation of the STAT family in PEDV-infected IPEC-J2 cells

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Transcriptome analysis reveals modulation of the STAT family in PEDV-infected IPEC-J2 cells. Such diseases cause considerable economic losses in the global swine industry. Enhancing our knowledge of PEDV-induced transcriptomic responses in host cells is imperative to understanding the molecular mechanisms involved in the immune response. Results: In total, 854 genes were significantly differentially expressed after PEDV infection, including 716 upregulated...

New insights into the Manila clam and PAMPs interaction based on RNA-seq analysis of clam through in vitro challenges with LPS, PGN, and poly(I:C)

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To understand the molecular basis of the immune response to pathogen-associated molecular patterns (PAMPs) in R. philippinarum response to different PAMPs. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.. Recently, the whole-genome...

Transcriptomic analysis of immune response to bacterial lipopolysaccharide in zebra finch (Taeniopygia guttata)

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Background: Despite the convergence of rapid technological advances in genomics and the maturing field of ecoimmunology, our understanding of the genes that regulate immunity in wild populations is still nascent.. Taking advantage of the fully sequenced genome of zebra finch, total RNA was isolated, sequenced, and partially annotated in these tissue/cells.. Results: In hypothalamus, there were 707 significantly upregulated transcripts,...

Signatures of selection for resistance to Haemonchus contortus in sheep and goats

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Signatures of selection for resistance to Haemonchus contortus in sheep and goats. The environmental conditions in the southern United States are ideal for the survival of the most pathogenic gastrointestinal nematode, Haemonchus contortus. This selection process increases the prevalence of particular alleles in sheep and goats and creates unique genetic patterns in the genome of these species. Directional selection was...

Genome-wide localization of the polyphenol quercetin in human monocytes

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Genome-wide localization of the. Background: Quercetin is a polyphenol of great interest given its antioxidant activity and involvement in the immune response. We demonstrate that upon binding to DNA or genome-associated proteins, quercetin acts as a cis-regulatory transcription factor for the expression of genes that are involved in the cell cycle, differentiation and development.. Polyphenols in gen- eral, and quercetin...

DNA methylation analysis of porcine mammary epithelial cells reveals differentially methylated loci associated with immune response against Escherichia coli challenge

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differentially methylated loci associated with immune response against Escherichia coli challenge. In the present study, we sought to determine DNA methylation changes induced by the mastitis causing Escherichia coli ( E. 0.01) differentially methylated CpG sites at 3 h and 24 h after E. Significantly, hypomethylated CpG sites were found in the promoter regions of immune response genes such as...

Acting locally - affecting globally: RNA sequencing of gilthead sea bream with a mild Sparicotyle chrysophrii infection reveals effects on apoptosis, immune and hypoxia related genes

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The systemic reaction in the spleen was much higher than that at the parasite attachment site (local) (1240), and higher than in liver (334). Vegetable and animal production face the challenge to feed the rapidly growing human population, and aquaculture is expected to be a major provider, with a constant increase in volume and number of farmed species in the...

Identification and analysis of long noncoding RNAs in response to H5N1 influenza viruses in duck (Anas platyrhynchos)

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Background: Long non-coding RNAs (lncRNAs) are important component of mammalian genomes, where their numbers are even larger than that of protein-coding genes. 22,630) have more lncRNA genes than protein-coding genes in the. Recently, mammalian lncRNAs were reported to play critical roles in immune response to influenza A virus infections. We then collected 151,970 assembled transcripts from RNA-Seq data of 21...

Comparative transcriptomic analysis of bovine papillomatosis

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US Department of Agri- culture (USDA) data show that Brazil is the second lar- gest producer of commercial beef of the world, with annual production of 2.586 million tons. These data show the strategic position of cattle in the country’s economy. The process of viral infection is coupled to replication of the viral genome. Studies have shown that the virus...

Multiple environmental stressors induce complex transcriptomic responses indicative of phenotypic outcomes in Western fence lizard

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Malaria infection elicited enriched expression of multiple immune-related functions likely corresponding to increased white blood cell (WBC) counts. Conclusions: Despite these findings, the lizards demonstrated immune resilience to malaria infection under food limitation with transcriptional results indicating a fully competent immune response to malaria, even under bio- energetic constraints. responses that were retained in the TNT x malaria combined exposure....

Daphnia galeata responds to the exposure to an ichthyosporean gut parasite by down-regulation of immunity and lipid metabolism

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Background: Regulatory circuits of infection in the emerging experimental model system, water flea Daphnia and their microparasites, remain largely unknown. Here we provide the first molecular insights into the response of Daphnia galeata to its highly virulent and common parasite Caullerya mesnili, an ichthyosporean that infects the gut epithelium. control) Daphnia, at two time points (4 and 48 h) after...