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Chủ đề : Drosophila melanogaster


Có 17+ tài liệu thuộc chủ đề "Drosophila melanogaster"

Dense time-course gene expression profiling of the Drosophila melanogaster innate immune response

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profiling of the Drosophila melanogaster innate immune response. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. BMC Genomics https://doi.org/10.1186/s . In this study, we performed a dense time-course RNA- seq analysis of the Drosophila transcriptional response to commercial E. coli-derived crude lipopolysaccharide (LPS), which activates the Imd pathway [21], to better understand the dynamics of activation and resolution of...

The genetic basis of diurnal preference in Drosophila melanogaster

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The genetic basis of diurnal preference in Drosophila melanogaster. Background: Most animals restrict their activity to a specific part of the day, being diurnal, nocturnal or crepuscular. The genetic basis underlying diurnal preference is largely unknown. Although time is one of the most important dimensions that define the species ecological niche, it is often a neglected research area [1]. Most...

A catalog of CasX genome editing sites in common model organisms

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A catalog of CasX genome editing sites in common model organisms. In this paper I characterized the CasX-compatible genome editing sites in the reference genomes of yeast (Saccharomyces cerevisiae), flatworms (Caenorhabditis elegans), flies (Drosophila melanogaster), zebrafish (Danio rerio), mouse (Mus musculus), rats (Rattus norvegicus), and humans (Homo sapiens). I also annotated sites in the GRCm38 reference and 15 additional mouse...

How do Wolbachia modify the Drosophila ovary? New evidences support the “titration-restitution” model for the mechanisms of Wolbachia-induced CI

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titration-restitution ” model for the mechanisms of Wolbachia-induced CI. However, eggs carrying the same strain of Wolbachia can rescue this embryonic death, thus producing viable Wolbachia-infected offspring. which hypothesized that Wolbachia titrated-out some factors from the sperm and the Wolbachia in the egg would restitute the factors after fertilization. Results: By RNA-seq analyses, we first compared the transcription profiles of...

Aging in the Drosophila ovary: Contrasting changes in the expression of the piRNA machinery and mitochondria but no global release of transposable elements

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Aging in the Drosophila ovary: contrasting changes in the expression of the piRNA. Background: Evolutionary theory indicates that the dynamics of aging in the soma and reproductive tissues may be distinct. In the soma, changes in the landscape of heterochromatin have been proposed to have an important role in aging. A role for changes in the chromatin landscape in the...

Identification and characterization of novel conserved RNA structures in Drosophila

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melanogaster made use of sequence-based alignments and employed a sliding window approach, inevitably biasing identification toward RNAs encoded in the more conserved parts of the genome.. While a sixth of the CRSs were ubiquitously expressed, we found that most were expressed in specific developmental stages or cell lines. Conclusions: This study provides a more comprehensive view of the ncRNA transcriptome...

Analysis of Drosophila melanogaster testis transcriptome

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morphological changes of the developing cysts in Drosophila melanogaster testis. The apical tip of the testis is enriched with somatic hub cells, germ-line stem cells enclosed by cyst progenitor cells and the dividing gonialblast cells. each one, are found in the middle region of the testis.. Enzymes and structural components of the mitochon- dria are synthesized mainly from the nuclear...

Transcriptome analysis reveals mechanisms of geroprotective effects of fucoxanthin in Drosophila

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Transcriptome analysis reveals mechanisms of geroprotective effects of fucoxanthin in Drosophila. Background: We have previously showed that the carotenoid fucoxanthin can increase the lifespan in Drosophila melanogaster and Caenorhabditis elegans. However, the molecular mechanisms of the geroprotective effect of fucoxanthin have not been studied so far.. Results: Here, we studied the effects of fucoxanthin on the Drosophila aging process at...

Transcription start site profiling uncovers divergent transcription and enhancerassociated RNAs in Drosophila melanogaster

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Full list of author information is available at the end of the article. Prior to RNA polymerase II (RNA pol II) engaging with DNA at the TSS, nucleosome depletion directly upstream of the TSS facilitates assembly of the PIC and other general transcription factors. In general, sites of initiation unassociated with annotated gene promoters have a high propensity for nucleosome...

A cis-regulatory element promoting increased transcription at low temperature in cultured ectothermic Drosophila cells

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Full list of author information is available at the end of the article. Our identification and functional dissection of the pst_E1 enhancer demonstrate the utility of resources and assay. At the transcriptional level, considerable progress has been made in case of the heat shock response (HSR), which was discovered early on. transcriptional induction of all of the many heat-shock induced...

SWI/SNF regulates half of its targets without the need of ATP-driven nucleosome remodeling by Brahma

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Background: Brahma (BRM) is the only catalytic subunit of the SWI/SNF chromatin-remodeling complex of Drosophila melanogaster. However, recent studies have provided evidence for a non-catalytic function of BRM in the transcriptional regulation of a few specific genes.. Results: Here we have used RNA-seq and ChIP-seq to identify the BRM target genes in S2 cells, and we have used a catalytically...

Order Diptera as a model in the studies of insect immunity: a review

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With respect to studies of insect immunity, two of the main pathways of immune response initiation, the Toll and IMD pathways, were elucidated first in Drosophila (De Gregorio et al., 2002. Parthier et al., 2014). Myllymäki et al., 2014). They are, however, sensitive to infection with the Drosophila C virus (DCV) (Dostert et al., 2005).. In Drosophila, the PGRP-SA group...

The effect of streptomycin on survival, development, and some biochemical aspects of Drosophila melanogaster

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The effect of streptomycin on survival, development, and some biochemical aspects of Drosophila melanogaster. While insects can able to tolerate applied antibiotic agents in various ways related to dietary concentrations, the right proportion of additional antibiotics on artificial diets should be able to prevent microbial contamination but not exert their negative effects on the insect (Thakur et al., 2016. Nair...

Knock-down gen Ubiquitin Carboxy-terminal Hydrolase (duch) gây giảm biểu hiện tyrosine hydroxylase trong tế bào thần kinh sản sinh dopamine và cảm ứng apoptosis trên mô hình ruồi giấm Drosophilamelanogaster

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KNOCK­DOWN GEN Ubiquitin Carboxy­terminal Hydrolase (duch) GÂY GI M BI U HI N TYROSINE HYDROXYLASE Ả Ể Ệ. TRONG T BÀO TH N KINH S N SINH DOPAMINE VÀ C M NG Ế Ầ Ả Ả Ứ APOPTOSIS TRÊN MÔ HÌNH RU I GI M Ồ Ấ Drosophilamelanogaster. Đ ng Ng c Ánh S ặ ọ ươ ng, Tr n ...