Tìm thấy 18+ kết quả cho từ khóa "Pancreatic ductal adenocarcinoma"
tailieu.vn Xem trực tuyến Tải xuống
Prognostic value of immune factors in the tumor microenvironment of patients with pancreatic ductal adenocarcinoma. Results: PDAC patients with a high density of TILs in the TME or PD-1-positive T cells in tertiary lymphoid aggregates (TLAs) demonstrated a significantly better prognosis than those with a low density of TILs or PD-1- negativity, respectively.
tailieu.vn Xem trực tuyến Tải xuống
Pancreatic fibrosis, acinar atrophy and chronic inflammation in surgical specimens associated with survival. in patients with resectable pancreatic ductal adenocarcinoma. We, therefore, investigated the potential role of histological chronic pancreatitis findings and chronic inflammation on surgical PDAC specimens and disease-specific survival (DSS)..
tailieu.vn Xem trực tuyến Tải xuống
Patients with metastatic pancreatic ductal adenocarcinoma previously treated with gemcitabine-based therapy received nal-IRI (80 mg/m 2 ) with 5-FU/LV every 2 weeks. Results: Fifty-one patients received nal-IRI plus 5-FU/LV between January 2015 and December 2020. Conclusions: Nal-IRI plus 5-FU/LV seems to be effective, with manageable toxicities, following gemcitabine-based treatment in patients with metastatic pancreatic ductal adenocarcinoma.
tailieu.vn Xem trực tuyến Tải xuống
A phase I study of the safety and activity of K-001 in patients with advanced pancreatic ductal adenocarcinoma. The current study aimed to evaluate safety and antitumor activity of K-001 in patients with advanced PDAC.. Methods: In this phase I, open-label trial, patients with advanced PDAC were recruited to a dose-escalation study in a standard 3 + 3 design. Results: Eighteen patients with advanced PDAC were screened, and twelve eligible patients were analyzed in the study.
tailieu.vn Xem trực tuyến Tải xuống
Pancreatic cancer. https://doi.org/10.1016/S . Optimizing the outcomes of pancreatic cancer surgery. https://doi.org/10.1038/s . A systematic review of the prognostic value of lymph node ratio, number of positive nodes and total nodes examined in pancreatic ductal adenocarcinoma. https://doi.org/10.1308/rcsann.2016.0340.. https://doi.org/10.1097/. https://doi.org/10.1245/.
tailieu.vn Xem trực tuyến Tải xuống
Additionally, considering that histo- logically different PAAD types arising from different cells may present differing prognoses, we further evalu- ated the predictive power of the signature in patients with pancreatic ductal adenocarcinoma (PDAC).
tailieu.vn Xem trực tuyến Tải xuống
In terms of availability of effective therapies, pancreatic ductal adenocarcinoma (PDAC) remains a challenging tumor both due to the intracorporeal location of the pancreas and strong resistance that rapidly develops to chemotherapy (Swayden et al., 2018). Most PDAC cases are diagnosed at late stages where the tumor has already metastasized and/or surgical intervention is no longer possible (Moletta et al., 2019).
tailieu.vn Xem trực tuyến Tải xuống
High accuracy differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma by immunoglobulin G glycosylation
tailieu.vn Xem trực tuyến Tải xuống
Also, several mathematical models have been conducted on the anti- tumor effect of Anti-CD25 and 5-FU. 25], the effect of anti-CD25 immunotherapy in combin- ation with 5-FU chemotherapy on pancreatic ductal adenocarcinoma has not assessed so far.
tailieu.vn Xem trực tuyến Tải xuống
Table 1 List of proteins associated with cancer stem cells that were upregulated in spheres compared to adherent cells of pancreatic cancer cell lines. 1 Validation GLRX3 expression in pancreatic cancer cell lines: A-B GLRX3 expression in pancreatic cancer cell lines. A GLRX3 mRNA was expressed in various pancreatic cancer cell lines. B GLRX3 protein was expressed in various pancreatic cancer cell lines.
tailieu.vn Xem trực tuyến Tải xuống
Normal pancreatic tissue ( n = 4), pancreatic cancer tissue ( n = 178. a the expression of S100A in human pancreatic cancer lines (PANC-1, CFAPC-1, MIA PaCa-2 and ASPC-1), and human pancreatic cell line hTERT-HPNE were measured by real-time PCR. b the expression of S100A in pancreatic cancer tissues, which were from three PDAC patients undergoing surgery, were measured by real-time PCR.
tailieu.vn Xem trực tuyến Tải xuống
Influence of resection margins and treatment on survival in patients with pancreatic cancer: meta-analysis of randomized controlled trials.. Increased survival in pancreatic cancer with nab-paclitaxel plus gemcit- abine. Conroy T, Desseigne F, Ychou M, Bouche O, Guimbaud R, Becouarn Y, et al.. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. Proposed Modifica- tion of the 8th Edition of the AJCC Staging System for Pancreatic Ductal Adenocarcinoma.
tailieu.vn Xem trực tuyến Tải xuống
MiR-615 inhibits cell proliferation, migration and invasion by targeting EGFR in human glioblastoma. miR-615 inhibits prostate cancer cell proliferation and invasion by directly targeting Cyclin D2. miR-615-5p is epigenetically inactivated and functions as a tumor suppressor in pancreatic ductal adenocarcinoma. Hsa_cir- cRNA_002144 promotes growth and metastasis of colorectal cancer through regulating miR-615-5p/LARP1/mTOR pathway
tailieu.vn Xem trực tuyến Tải xuống
Body mass index and risk, age of onset, and survival in patients with pancreatic cancer. McWilliams RR, Matsumoto ME, Burch PA, et al. Yuan C, Bao Y, Wu C, et al. Prediagnostic body mass index and pancreatic cancer survival. Varghese AM, Singh I, Singh R, et al. Obesity and survival in population-based patients with pancreatic cancer in the San Francisco Bay Area. Olson SH, Chou JF, Ludwig E, et al. Kasenda B, Bass A, Koeberle D, et al
tailieu.vn Xem trực tuyến Tải xuống
A study on pancreatic ductal adenocarcinoma using WGCNA identified 5 modules and found 10 hub genes that may indicate a poor prognosis [10].. In this study, we applied this method to identify key modules and hub genes associated with cSCC and AK.. We also tested whether the expression of hub genes could predict survival outcomes in other cancers using TCGA pan-cancer data.. We selected the genes with standard deviations in the top 50% for further ana- lysis.
tailieu.vn Xem trực tuyến Tải xuống
A study conducted by Lembeck et al. [2], showed a significant association between high MPV and worse prognosis in patients with pancreatic ductal adenocarcinoma regardless of the normalized level of other well-known prognostic markers. Although review by Budak et al. Aydogan et al. Amin et al. [13] found that higher level of PDW in patients with vaso-oc- clusive crisis in the course of sickle cell disease can be contributed to megakarycote hyperplasia..
tailieu.vn Xem trực tuyến Tải xuống
Conditional survival in patients with pancreatic ductal adenocarcinoma resected with curative intent. org/10.1002/cncr.26553.. Spolverato G, Kim Y, Ejaz A, Alexandrescu S, Marques H, Aldrighetti L, et al.. https://doi.org/10.1001/jamasurg.2015.0219.. https://doi.org . Margonis G, Buettner S, Andreatos N, Wagner D, Sasaki K, Barbon C, et al.. https://doi.org/10.1097/SLA .
tailieu.vn Xem trực tuyến Tải xuống
High expression of AFAP1-AS1 is associated with poor survival and short-term recurrence in pancreatic ductal adenocarcinoma. The up-regulation of long non-coding RNA AFAP1-AS1 is associated with the poor prognosis of NSCLC patients. Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
tailieu.vn Xem trực tuyến Tải xuống
Pancreatic Cancer. Pancreatic Cancer: Introduction. These tumors occur twice as frequently in the pancreatic head compared to the rest of the organ, and tend to be aggressive, often presenting when locally inoperable or after distal metastases have occurred. Patients with pancreatic cancer have a poor prognosis, with a 5-year survival of only 5%. The discussion of pancreatic cancer here will be limited to ductal adenocarcinomas.
tailieu.vn Xem trực tuyến Tải xuống
ductal adenocarcinoma (Vychytilova-Faltejskova et al., 2015), Esophageal Squamous Cell Carcinoma (ESCC) (Wang et al., 2015b), and colorectal cancer (Wang et al., 2015a).