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Chủ đề : Circular RNA


Có 10+ tài liệu thuộc chủ đề "Circular RNA"

Genome-wide identification of circular RNAs in peanut (Arachis hypogaea L.)

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However, there have been no related studies on the number of circRNAs and their overall characteristics including circRNA abundance and expression profiles in peanut, which is one of the most important edible oil seed crops in the world.. Conclusions: We present the first systematical investigation of the genomic characteristics and expression profiles of circRNAs in peanut. 2019 Open Access This...

Dynamic expression and functional analysis of circRNA in granulosa cells during follicular development in chicken

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Dynamic expression and functional analysis of circRNA in granulosa cells during. follicular development in chicken. The granulosa cells of follicles play a determining role in ovarian development.. The majority of the splice lengths of circRNAs were 200 – 500 nt and mainly produced from intron and CDS regions. During follicle growth, differentially expressed (DE) circRNAs showed dynamic changes which were...

Differentially expressed non-coding RNAs induced by transmissible gastroenteritis virus potentially regulate inflammation and NF-κB pathway in porcine intestinal epithelial cell line

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Differentially expressed non-coding RNAs induced by transmissible gastroenteritis virus potentially regulate inflammation and NF- κ B pathway in porcine intestinal. A total of 523 mRNAs, 65 microRNAs (miRNAs), and 123 circular RNAs (circRNAs) were differentially expressed. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed differentially expressed mRNAs were linked to inflammation-related pathways, including NF- κ B, Toll-like receptor, NOD-like...

CircMarker: A fast and accurate algorithm for circular RNA detection

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CircMarker: a fast and accurate algorithm for circular RNA detection. Non-canonical splicing joins 3’ and 5’ and forms the so-called circular RNA.. It is now believed that circular RNA plays important biological roles such as affecting susceptibility of some diseases.. During the past several years, multiple experimental methods have been developed to enrich circular RNA while degrade linear RNA. Although...

Changing expression profiles of long noncoding RNAs, mRNAs and circular RNAs in ethylene glycol-induced kidney calculi rats

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Background: To explore long non-coding RNA (lncRNA), mRNA and circular RNA (circRNA) expression profiles and their biological functions in the pathogenesis of kidney stones in ethylene glycol-induced urolithiasis rats.. Results: The expression of 1440 lncRNAs, 2455 mRNAs and 145 circRNAs was altered in the kidneys of urolithiasis rats. mRNAs coexpressed with lncRNAs were involved in many kidney diseases, e.g., Ephb6...

Construction and comprehensive analysis of a ceRNA network to reveal potential prognostic biomarkers for lung adenocarcinoma

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The DEGs in the ceRNA network of hsa_circ_0049271 enriched in biological processes of cell proliferation and the Jak-STAT signaling pathway. We also detected 7 mRNAs in the ceRNA network of hsa_circ_0049271 that were significantly associated with the overall survival of LUAD patients ( P <. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. The Creative Commons Public Domain Dedication...

Plasma circN4BP2L2 is a promising novel diagnostic biomarker for epithelial ovarian cancer

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Plasma circN4BP2L2 is a promising novel diagnostic biomarker for epithelial ovarian cancer. By circRNA-sequencing analysis, we previously found that circN4BP2L2 was signifi- cantly decreased in epithelial ovarian cancer (EOC) tissues, and was predictive of disease progression. CircN4BP2L2 could significantly separate EOC from benign (AUC = 0.82, P <. 0.01) or normal (AUC = 0.90, P <. Early stage EOC vs...