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Chủ đề : mitochondrial DNA


Có 15+ tài liệu thuộc chủ đề "mitochondrial DNA"

Yes, we can use it: A formal test on the accuracy of low-pass nanopore long-read sequencing for mitophylogenomics and barcoding research using the Caribbean spiny lobster Panulirus argus

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Background: Whole mitogenomes or short fragments (i.e bp of the cox1 gene) are the markers of choice for revealing within- and among-species genealogies. Second, I explored the accuracy of the long-read assembled genomes by comparing them to a ‘ gold ’ standard reference mitogenome retrieved from the same individual using Illumina sequencing. To accomplish these goals, I used the Caribbean...

Association of mitochondrial DNA haplogroups J and K with low response in exercise training among Finnish military conscripts

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haplogroups J and K with low response in exercise training among Finnish military conscripts. Background: We have previously suggested that some of the mutations defining mitochondrial DNA (mtDNA) haplogroups J and K produce an uncoupling effect on oxidative phosphorylation and thus are detrimental for elite endurance performance. Here, the association between haplogroups J and K and physical performance was determined...

Genome sequencing of the neotype strain CBS 554.65 reveals the MAT1–2 locus of Aspergillus niger

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Genome sequencing of the neotype strain CBS 554.65 reveals the MAT1 – 2 locus of Aspergillus niger. Its genome was one of the first Aspergillus. Results: The genome of CBS 554.65 was sequenced with PacBio. The assembly covered all the 8 centromeric regions of the chromosomes. A nucleotide alignment showed a different orientation of the MAT1 – 1 locus of...

Big data analysis of human mitochondrial DNA substitution models: A regression approach

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Background: We study Phylotree, a comprehensive representation of the phylogeny of global human mitochondrial DNA (mtDNA) variations, to better understand the mtDNA substitution mechanism and its most influential factors.. Partitioning a model by a factor ’ s value results in several sub-models (one for each value), where the likelihoods of the sub-models can be combined to form a score for...

Analysis of the canid Y-chromosome phylogeny using short-read sequencing data reveals the presence of distinct haplogroups among Neolithic European dogs

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Analysis of the canid Y-chromosome phylogeny using short-read sequencing data reveals the presence of distinct. Background: Most genetic analyses of ancient and modern dogs have focused on variation in the autosomes or on the mitochondria. Similar to that of the mitochondria and previous more limited studies of Y diversity, we observe several deep splits in the Y-chromosome tree which may...

A Sequel to Sanger: Amplicon sequencing that scales

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The present study tests the capacity of single molecule, real-time (SMRT) sequencing implemented on the SEQUEL platform to overcome these limitations, employing 658 bp amplicons of the mitochondrial cytochrome c oxidase I gene as a model system.. Be- cause of the latter constraint, Sanger sequencing is still widely used for amplicon characterization [6–9] despite its relatively high cost [10]. However,...

Multiple independent structural dynamic events in the evolution of snake mitochondrial genomes

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Multiple independent structural dynamic events in the evolution of snake. mitochondrial genomes. However, little attention has been paid to the changes in gene arrangement patterns in the snake ’ s mitogenome. Our purpose was to further investigate the evolutionary implications and possible rearrangement mechanisms of the mitogenome within snakes.. Within Scolecophidia, the O L was lost several times in Typhlopidae...

Independent impacts of aging on mitochondrial DNA quantity and quality in humans

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Conversely, mtDNA copy number decreased by an average of 0.4 copies per year ( β. Multiple regression analyses also showed that age had independent effects on mtDNA copy number decrease and heteroplasmy accumulation. Finally, mtDNA copy number was positively associated with serum bicarbonate level ( P = 4.46e-5), and inversely correlated with white blood cell count ( P = 0.0006)....

Analysis of genetic variation in an important pest, Tuta absoluta, and its microbiota with a new bacterial endosymbiont

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Saidov et al., 2018).. Mansour et al., 2018). Kanle Satishchandra et al., 2019), as well as solanaceous weeds (Shashank et al., 2018). The interactions between bacterial microorganisms and their hosts are important in terms of the host’s fitness, ecology, and evolutionary biology (Gurung et al., 2019).. Stouthamer et al., 1999). Moran et al., 2008. Charlat et al., 2009. Richardson et...

Neutrophil extracellular trap formation and nuclease activity in septic patients

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Neutrophil extracellular trap formation and nuclease activity in septic patients. Thus, we tested the hypotheses that 1) NET formation from neutrophils of septic patients is increased compared to healthy volunteers, both without stimulation and following incubation with mitochondrial DNA (mtDNA), a damage-associated molecular pattern, or phorbol 12-myristate 13-acetate (PMA. Methods: Following ethic committee approval, we included 18 septic patients and...

First record of Ahaetulla mycterizans (Linnaeus, 1758) (Serpentes: Colubridae) from the Lesser Sunda region, Indonesia, based on molecular and morphological identification

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First record of Ahaetulla mycterizans (Linnaeus, 1758) (Serpentes: Colubridae) from the Lesser Sunda region, Indonesia, based on molecular and morphological identification. The arboreal snake genus Ahaetulla (Link, 1807) is composed of 8 species distributed in most countries of the Asian region, including Indonesia, Malaysia, Thailand, Myanmar, India, Sri Lanka, and throughout the Indochinese Peninsula (Das, 2015. Mohapatra et al., 2017).....

Cytochrome B based genetic relationship of wild boars from Dak Nong province of Vietnam

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CYTOCHROME B BASED GENETIC RELATIONSHIP OF WILD BOARS FROM DAK NONG PROVINCE OF VIETNAM. This study aimed to estimate the genetic relationship of wild boars from Dak Nong province by cytochrome b. The sequence alignment showed 26 single-nucleotide polymorphisms (SNPs) between haplotypes from Dak Nong with others from Asia and Europe. The haplotype DKN3 and Vietnamese native wild boar haplotypes...

ADN cho biết tổ tiên của mình

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ADN cho biết tổ tiên của mình. Ngày nay chỉ cần chưa tới một khoản tiền vài trăm đô la là người ta có thể góp phần chấm dứt bao tranh cãi tốn giấy mực về nguồn gốc của tổ tiên minh từ nhiều thập kỷ qua. ít ra, đó là khoản tiền cần có để một người tìm lại...