Tìm thấy 20+ kết quả cho từ khóa "Cancer cells"
tailieu.vn Xem trực tuyến Tải xuống
(A) OVCAR3 ovarian cancer cells on tissue culture dish were exposed to ultrasound. cancer cells were added with fluorescence labeled Taxol analog (488-PTX) (1 nM) for 60 min. OVCAR3 ovarian cancer cells were added with fluorescence la- beled Taxol analog (488-PTX) (1 nM) for 60 min.
tailieu.vn Xem trực tuyến Tải xuống
The expression of OPRK1 in breast cancer cells and normal human mammary epithelial cellsin vitro. The cell lines of breast cancer cells including MDA- MB-231, MDA-MB-435 and MCF-7 cells as well as nor- mal human mammary epithelial cells of MCF-10A was. used to determine the protein expression of OPRK1 by western blot and RT-qPCR. After qualification of proteins expression, the OPRK1 expressions were higher in breast cancer cells than normal cells.
tailieu.vn Xem trực tuyến Tải xuống
In brief, colon cancer cells were seeded in 96-well plates at a density of 2500 cells/well. Colon cancer cells were dispersed as single cells, then seeded in 6-well plates (1500 cells/well). Briefly, colon cancer cells were digested as single cells, then seeded in 0.35% top agar at 10000 cells/well in 6-well plates. Cell cycle of colon cancer cells was evaluated by flow cy- tometry. cycle of colon cancer cells was then evaluated by Gallios Flow Cytometer (Beckman Coulter)..
tailieu.vn Xem trực tuyến Tải xuống
Therefore, the inhibition of survivin is thought to be a promising therapeutic strategy in cancer treatment (Peeryet al., 2017).. Moreover, CAPE has been demonstrated to selectively kill cancer cells (He et al. Murtaza et al. Therefore, it was aimed herein to investigate the anticancer effects of CAPE on RKO colorectal cancer cells and determine changes in the survivin expression following CAPE treatment..
tailieu.vn Xem trực tuyến Tải xuống
Thus, we may conclude that FMNL2 silencing inhib- ited cell proliferation in human breast cancer cells.. FMNL2 silencing inhibited EdU incorporation and induced cell cycle arrest in human breast cancer cells. Therefore, our findings demonstrated that FMNL2 silencing inhibited EdU in- corporation and induced cell cycle arrest in human breast cancer cells.. FMNL2 overexpression elevated cell proliferation in human breast cancer cells.
tailieu.vn Xem trực tuyến Tải xuống
However, the efficacy of the combination of BZM and MTX for prostate cancer treatment remains undeter- mined. Human prostate cancer LNCaP, 22RV1, PC-3 cells were obtained from ATCC (Manassas, VA, USA). CFSE- labelled prostate cancer cells were treated with indicated treatments for 24 h. To construct the mice Xenograft model, prostate cancer cells were implanted subcutaneously into the flanks of 6-week-old male SCID mice.
tailieu.vn Xem trực tuyến Tải xuống
Oncogenic role of ALX3 in cervical cancer cells through KDM2B-mediated histone demethylation of CDC25A. This work focused on the function of CDC25A in cervical cancer cell growth and the molecules involved.. The CDC25A expression in cancer and normal tissues was predicted in the GEPIA database and that in CSCC and normal cells was determined by RT-qPCR and western blot assays.
tailieu.vn Xem trực tuyến Tải xuống
In colon cancer cells, increased cNrf2 (nuclear factor- like 2) expression promotes colorectal cancer with more aggressive tumors via upregulating PSMD4 (Lin et al., 2016). PSMD4 increases cell proliferation via regulation of the PTEN/Akt pathways in hepatocellular carcinoma (HCC) cells. These two parameters are a strong prognosis indicator in HCC (Jiang et al., 2019). Hypoxia increased transcriptional activity of all PSMD4 promoter constructs.
tailieu.vn Xem trực tuyến Tải xuống
Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells. We aimed to investigate the role of the EGFR and Src-mediated STAT3 signalling pathway in tamoxifen-resistant breast cancer cells.. Results: TamR cells showed decreased expression of estrogen receptor and increased expression of EGFR. TamR cells showed an acceleration of the G1 to S phase transition.
tailieu.vn Xem trực tuyến Tải xuống
MDA-MB-231 cells were found more sensitive to the compound compared to MCF-7 cells. In correlation with our result, Pilco-Ferreto and Calaf (2016) showed that MDA-MB-231 breast cancer cells were more sensitive to one of the quinone-based drugs, doxorubicin, compared to MCF-7 breast cancer cells. After our cytotoxicity results, we carried out advanced analyses to elucidate the compound’s mechanism of action.. The cell death mode was found to be apoptosis in MDA-MB-231 cells.
tailieu.vn Xem trực tuyến Tải xuống
However, in cancer cells, E2F6 has been shown to play a dual role as a transcriptional activator and repressor (Xu et al., 2007).. Here, we show that expression of E2F6 in breast tumor tissues and breast cancer cell lines is higher than in normal cells, supporting the view that E2F6 can be overexpressed in breast carcinomas (Palacios et al., 2005).
tailieu.vn Xem trực tuyến Tải xuống
The effects of PIKfyve inhibitor YM201636 on claudins and malignancy potential of nonsmall cell cancer cells. Lung cancer is one of the most common cancer type that is expected to be diagnosed in men and women in 2020 (Siegel, et al. Phosphorylation of the phosphatidylinositol-3-phosphate (PI3P) by PIKfyve generates phosphatidylinositol 3,5-bisphosphate [PtdIns(3,5)P2] or phosphatidylinositol 5-phosphate (PtdIns5P) (Shisheva, 2001). al., 2006.
tailieu.vn Xem trực tuyến Tải xuống
Bortezomib has been reported to induce apoptosis in cancer cells as an inhibitor of proteasome, and even green tea effectively antagonizes its ability to induce apoptosis in cancer cells by the bonds with the boronic acid portion of the bortezomib, with its epigallocatechin-3-gallate structure (Glynn et al., 2015)..
tailieu.vn Xem trực tuyến Tải xuống
When cancer cells acquire mesenchymal traits and simultaneously express epithelial features, this interphase state is described as hybrid E/M (Kroger et al., 2019). However, the function of E-cadherin in cancer remains elusive due to the existence of opposing results reported by different studies.
tailieu.vn Xem trực tuyến Tải xuống
Genome-wide segregation of single nucleotide and structural variants into single cancer cells. Background: Single-cell genome sequencing provides high-resolution details of the clonal genomic modifications that occur during cancer initiation, progression, and ongoing evolution as patients undergo treatment. One limitation of current single-cell sequencing strategies is a suboptimal capacity to detect all classes of single- nucleotide and structural variants in the same cells..
tailieu.vn Xem trực tuyến Tải xuống
For apoptosis analyses, cells were collected and stained by PI and FITC conjugated Annexin (TACS Annexin V-FITC kit, R&D system. Then, Cells were analyzed on a FACSAria (BD Biosciences, San Jose, CA) and cell distri- butions were modeled and calculated in FlowJo.. β -Lap-induced cytotoxicity in pancreatic cancer cells is NQO1-dependent. To test tumor specificity of β-lap, pancreatic cancer cells (MiaPaCa2, BxPC3, HS766T, or S2–013 cells) were used to examine the roles of NQO1.
tailieu.vn Xem trực tuyến Tải xuống
Results from Table 1 showed that stichoposide D exhibited strong inhibitory activity on the growth of NTERA-2 cells with the IC µM. not only inhibits cancer cells to growth but also significantly affects to cancer stem cells’. Chemical structure of stichoposide D isolated from the Vietnamese S. Determination of cytotoxic activities of stichoposide D on cancer cells and CSCs by SRB assay.. Stichoposide D triggers apoptosis in NTERA- 2 cancer stem cells.
tailieu.vn Xem trực tuyến Tải xuống
The differences in colony formation ability on soft agar of HeLa cells are presented. activity of these diterpenoids had been presented on liver cancer cells and colorectal cancer cells by inducing apoptosis via activating related signaling pathways [9-11].. However, so far, the effects of CK-EE on cervical cancer cells as well as on zebrafish (a living organism) have not been examined yet..
tailieu.vn Xem trực tuyến Tải xuống
Overexpression of lncRNA BRE-AS1 inhibits cancer cell proliferation, migration, and invasion by downregulating miR-21.. miR-21: MicorRNA-21. Western blot analysis of the expression of tumor suppressor PTEN, which is a target of miR-21 in cells of TNBC cell lines BT-549 (A) and HCC70 (B). The role of miR-21 in cancer. Diagnostic and prognostic value of circulating miR-21 for cancer: a systematic review and meta-analysis.
tailieu.vn Xem trực tuyến Tải xuống
Earlier studies reported that DOX downregulates PD-L1 expression on the cell surface of MDA-MB-231 breast cancer cells (Ghebeh et al., 2010). Because the DOX effect on PD-L1 expression in CRC cells is not known, we investigated the expression level of PD-L1 on DOX treatment in HCT116 colon cancer cells. We found that PD-L1 expression increased positively in DOX-treated HCT116 colorectal cancer cells and decreased in MDA- MB-231 breast cancer cells both in RNA and protein levels (Figure 1).