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Fatty liver

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Comparative transcriptomic analysis reveals an association of gibel carp fatty liver with ferroptosis pathway

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D: Nonalcoholic fatty liver disease. org/10.1186/s . samples in PC1 belong to fatty liver. NL: normal liver, FL: fatty liver.. Additional file 2: Table S1 DEGs (FDR ≤ 0.001) in normal liver and fatty liver.

Integrated analysis of the methylome and transcriptome of chickens with fatty liver hemorrhagic syndrome

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Briefly, for the fatty liver susceptible line, the initial Jingxing-Huang chickens (F0 generation) were induced by a high-fat diet, while the chickens were fed a basal diet for control line. In F1 generation, male chickens with FLHS in the fatty liver group and non-FLHS chickens in the control group were assessed. Apparent feature of fatty liver and normal liver. (a) Phenotype of fatty liver. Global methylation pattern (mCHG and mCHH) in fatty liver and normal liver.

Protein acetylation in mitochondria plays critical functions in the pathogenesis of fatty liver disease

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Relationships between fatty liver and fertility and some periparturient diseases in commercial Dutch dairy herds. Relevance of apolipoproteins in the development of fatty liver and fatty liver-related peripartum diseases in dairy cows. Serum paraoxonase-1 as biomarker for improved diagnosis of fatty liver in dairy cows. Natural history of nonalcoholic fatty liver disease: a prospective follow-up study with serial biopsies..

Changes of intestinal bacterial microbiota in coronary heart disease complicated with nonalcoholic fatty liver disease

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In fatty liver mice, serum ALT positively correlated with the abundance of Coprococcus [39]. The abundance of Bifidobacterium longum subsp infantis was lower in CHD patients than in HCs and was further decreased in CHD-NAFLD patients. Correlation analysis found it nega- tively correlated with the abundance of Akkermansia. In our study, the abundance of Akkermansia in the overall CHD patients was lower than that in HCs, which was consistent with previous studies [20, 21]..

Global analysis of expression, maturation and subcellular localization of mouse liver transcriptome identifies novel sex-biased and TCPOBOP-responsive long non-coding RNAs

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Finally, top enriched terms for the genes most highly enriched in the polyA-selected chromatin-bound fraction include ribosomal protein, oxidative phosphor- ylation/mitochondria, non-alcoholic fatty liver disease, and mRNA-splicing (Table S2F). 64-fold higher relative levels in the non-polyA-selected than in the polyA-selected fraction (Fig. All of these lncRNAs show their highest expression in the chromatin-bound, non-polyA-selected fraction across all four treatment groups (Fig.

Nhận xét tình trạng đề kháng insulin trên bệnh nhân gan nhiễm mỡ

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Kết quả: Chỉ số kháng nonalcoholic fatty liver disease insulin trong nhóm đối tượng nghiên cứu là Introduction: Survey on insulin resistance 77,5%, chỉ số kháng insulin tăng dần theo in patient with nonalcoholic fatty liver mức độ gan nhiễm mỡ (độ 1, 2, 3 lần lượt là disease.

Unique adaptations in neonatal hepatic transcriptome, nutrient signaling, and onecarbon metabolism in response to feeding ethyl cellulose rumen-protected methionine during late-gestation in Holstein cows

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Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Free radicals, lipid peroxidation and the antioxidant system in the blood of cows and newborn calves around calving. Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease. Energy metabolism and thermoregulation in the newborn calf. Neonatal immune development in the calf and its impact on vaccine response.

Ontogeny of hepatic metabolism in mule ducks highlights different gene expression profiles between carbohydrate and lipid metabolic pathways

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It would therefore be very interesting to determine the precise impact of the embry- onic thermal stimulus on the number of hepatic cells at birth and after overfeeding in order to accurately modu- late the final yield of fatty liver through a specific pro- gramming protocol.. In oviparous animals, the nutrition of the developing embryo depends entirely on the resources from yolk and albumen.

Tiểu luận Vai trò Fructose - Thực phẩm chức năng - Công nghệ thực phẩm IUH

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loét đại tràng Bowel Disease 10 ICQC The International Carbohydrate Quality Consortium 11 IDF International Diabetes Liên đoàn Đái tháo đƣờng Federation Quốc tế 20 LA n-6 linoleic acid (18:2n-6) 13 LCPUFAs Long-chain Các acid béo không no nhiều polyunsaturated fatty acids nối đôi mạch dài 7 LDL Low density Lipoprotein Cholesterol xấu 22 MA Mead acid (20:3n-9) 2 NAFLD Nonalcoholic fatty liver Bệnh gan nhiễm mỡ không do disease rƣợu 30 NDA Nutrition andAllergies Dinh dƣỡng và dị ứng 21 OA n-9 oleic

Mối liên quan giữa biến thể gen ADIPOQ rs266729 và bệnh đái tháo đường típ 2 ở người Việt Nam

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Association of Adiponectin Gene Polymorphism with Nonalcoholic Fatty Liver Disease in Taiwanese Patients with Type 2 Diabetes. Adiponectin gene polymorphisms and their effect on the risk of myocardial infarction and type 2 diabetes: an association study in an Italian population. Common adiponectin gene variants show different effects on risk of cardiovascular disease and type 2 diabetes in European subjects.

Multi-omics analysis reveals the glycolipid metabolism response mechanism in the liver of genetically improved farmed Tilapia (GIFT, Oreochromis niloticus) under hypoxia stress

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In this study, some of the DE genes in the liver of GIFT in response to acute hypoxia stress were related to the biosynthesis of unsat- urated fatty acids and fatty acid degradation. In animals, ELOVL6 is one of the key genes in the biosyn- thesis of unsaturated fatty acids and its expression levels are related to regulation of this pathway.

Targeted mutagenesis of Δ5 and Δ6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)

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LC-HUFA: Long-chain highly unsaturated fatty acids. FADS2: Fatty acid desaturases 2. Δ 5fad: Δ 5 fatty acid desaturase. Δ 6fad: Δ 6 fatty acid desaturase. https://doi.org/10.1016/j.aquaculture . https://doi.org/10.1038/srep21892.. https://doi.org . https://doi.org/10.1093/jn . https://doi.org/10.1111/mec.14533.. Genetic effects of fatty acid composition in muscle of Atlantic salmon. https://doi.org/10.1016/j.bbalip .

Endogenous circadian time genes expressions in the liver of mice under constant darkness

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Drug metabolism in the liver.. Sex differences in the circadian variation of cytochrome p450 genes and. Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock

Transcriptomic analyses suggest a dominant role of insulin in the coordinated control of energy metabolism and ureagenesis in goat liver

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The effect of implantation of anabolic steroids into suckling and ruminating lambs on the metabolism of alanine in livers perfused in the presence or absence of volatile fatty acids. Regulation of enzymes of the urea cycle and arginine metabolism. Hepatic glutamine metabolism under the influence of the portal ammonia concentration in the perfused rat liver. Production of volatile fatty acids in the rumen and cecum-colon of steers as affected by forage:concentrate and forage physical form.

Transcriptome analyses of liver in newlyhatched chicks during the metabolic perturbation of fasting and re-feeding reveals THRSPA as the key lipogenic transcription factor

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Sterol response element-binding protein 1c (SREBP1c) is involved in the polyunsaturated fatty acid suppression of hepatic S14 gene transcription

Integrative analysis of transcriptomic data related to the liver of laying hens: From physiological basics to newly identified functions

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In the present study (Additional file 2), many genes involved in fatty acid synthesis are over-expressed at sexual maturity (FAR1, ACSBG2, ELOVL2, HADHB, ELOVL1, PEX11A, ACSM3, LPPR5, ACPL2, PECR. Similarly, the expression of some genes involved in the intracellular fatty acids binding and lipid transport [67] is also stimulated (FABP3, OSBPL3, TEX2, DBI, COL4A3BP, TTPA, MTTPL, Additional file 2).

Global investigation of estrogen-responsive genes regulating lipid metabolism in the liver of laying hens

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Conclusions: These results increase our understanding of the functional network of estrogen in chicken liver and also reveal aspects of the molecular mechanism of estrogen-related lipid metabolism.. Liver is the central organ of lipid metabolism, especially in chicken, where more than 90% of the de novo synthe- sis of fatty acids takes place [1–3].

Dynamic accumulation of fatty acids in duck (Anas platyrhynchos) breast muscle and its correlations with gene expression

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Genetic architecture of fatty acid composition in the longissimus dorsi muscle revealed by genome-wide association studies on diverse pig populations. Transcriptome analyses reveal genes and pathways associated with fatty acid composition traits in pigs. Effects of dietary n-6:n-3 PUFA ratios on lipid levels and fatty acid profile of Cherry Valley ducks at 15-42 days of age. chemical and fatty acid composition of meat and liver of wild ducks ( Anas platyrhynchos.

Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver

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Analysis of the microarray data shows that Sod, the SOD-copper chaperone (Ccs), and catalase display lower levels of transcription in fluke-infected liver compared with the liver from non-infected animals (Fig. In response to the high oxidative stress-induced envir- onment of the liver, the immature flukes express an anti- oxidant defence system that is comparable to that of its mammalian hosts (Fig.

VAI TRÒ CUẢ OMEGA-3 FATTY ACIDS TRONG VIỆC ĐIỀU TRỊ VÀ PHÒNG NGỪA BỆNH

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Omega-3 fatty acid và n-6 fatty acids là những chất béo không bão hoà (polyunsaturated fatty acids-PUFA) vì chúng không thể tổng hợp được trong cơ thể. Nguồn gốc chính cuả 18-carbon fatty acids (linoleic acid-LNA) là hạt flaxeed, hạt đậu nành, canola, và hạt bông gòn, hạt lúa mì và dầu walnut. Cá và dầu cá là nguồn gốc của 20- và 22- fatty acids. Sự biến đổi của n-3 và n-6 fatty acids dùng những diếu-tố giống nhau.