Có 40+ tài liệu thuộc chủ đề "Breast Cancer"
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Only patients with HER2+ breast cancer without BM. 50 years in Maurer et al. [26] and Brufsky et al.. Breast Cancer Assay) [21], distant relapse in ≤2 years [22], first distant relapse at a visceral site [23], and nodal involvement [26]. anti-HER2 treatment. In Ahn et al. [17], Berghoff et al. [30], and Brufsky et al. Niwinska et al. Braccini...
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The aim of this study was to estimate the prevalence of different types of CVD in women diagnosed with BC compared to cancer-free controls as well as the incidence of CVD after BC diagnosis. We followed 16,505 cancer-nạve BC patients diagnosed from 2003 to 2007 5 years before and up to 10 years after BC diagnosis compared to 165,042 cancer-free...
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Exposure to low intensity ultrasound removes paclitaxel cytotoxicity in breast and ovarian cancer cells. Results: In exploring methods to modulate activity of paclitaxel in causing cancer cell death, we unexpectedly found that a brief exposure of paclitaxel-treated cells in culture to low intensity ultrasound waves prevented the paclitaxel-induced cytotoxicity and death of the cancer cells. To view a copy of...
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Weight changes according to treatment in a diverse cohort of breast cancer patients. Background: Weight changes are common among breast cancer patients. The majority of studies to date have focused on weight gain after a breast cancer diagnosis and its implications on health in survivors. Fewer studies have examined weight loss and its related characteristics. We evaluated weight changes during...
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Results: Confirmatory factor analysis confirmed Watson ’ s original structure underlying the Mini-MAC items:. Absolute, incremental, and parsimonious fit indices showed a highly significant level of acceptance confirming a good performance of the measurement model. and both convergent and discriminant validity tests indicated that the Arabic version of the Mini-MAC had a good performance and may serve as a valid...
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Short-term serial assessment of electronic patient-reported outcome for depression and anxiety in breast Cancer. Purpose: The incidence of depression and anxiety is higher in patients with breast cancer than in the general population. We evaluated the degree of depression and anxiety and investigated the changes in patients with breast cancer during the treatment period and short-term follow-up period.. Methods: Overall,...
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Association of body composition with odds of breast cancer by molecular subtype:. analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study. Background: The association between obesity and breast cancer (BC) has been extensively studied among US, European and Asian study populations, with often conflicting evidence. To view a copy of this...
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Herein, we aimed to explore the expression pattern and clinical implications of BATF2 in breast cancer (BC).. Methods: We assessed the differences in BATF2 mRNA expression between cancerous and noncancerous tissues in BC using GEPIA and UALCAN data and in BATF2 protein expression pattern using Human Protein Atlas (HPA) data.. The association between the differentially expressed BATF2 mRNA and BC...
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Cognitive functioning and its associated factors among breast cancer patients on chemotherapy at Tikur Anbessa specialized hospital, Addis Ababa Ethiopia: an. Background: Breast cancer is the second leading cause of cancer in the world. Cognitive problems are common among breast cancer patients. The study aimed to assess cognitive functioning and its associated factors among breast cancer patients at Tikur Anbessa...
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Rationale and design of the Diet Restriction and Exercise-induced Adaptations in. Full list of author information is available at the end of the article. Methods: Fifty patients with measurable metastases and primary breast cancer starting a new line of intravenous chemotherapy will be randomly assigned to usual care or the combined diet and exercise intervention. Participants assigned to the intervention...
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Highly heterogeneous-related genes of triple-negative breast cancer: potential diagnostic and prognostic biomarkers. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.. https://doi.org/10.1186/s . Triple- negative (ER-, PR-, and HER2-) breast cancer (TNBC), a...
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Identification of the prognostic value of. ferroptosis-related gene signature in breast cancer patients. Background: Breast cancer (BRCA) is a malignant tumor with high morbidity and mortality, which is a threat to women ’ s health worldwide. Ferroptosis is closely related to the occurrence and development of breast cancer.. The Kaplan-Meier (K-M) and Receiver Operating Characteristic (ROC) curves were plotted to...
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Extending screening intervals for women at low risk of breast cancer: do they find it. Background: Trials of risk estimation in breast cancer screening programmes, in order to identify women at higher risk and offer extra screening/preventive measures, are ongoing. It may also be feasible to introduce less frequent screening for women at low-risk of breast cancer. This study aimed...
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Response to neoadjuvant chemotherapy based on pathologic complete response in very young patients with ER-positive breast cancer: a large, multicenter, observational study. While very young patients respond better to chemotherapy, chemotherapy is less effective in ER-positive tumors than in ER-negative tumors. The authors tried to evaluate chemotherapy response of very young patients with ER- positive BC by pathologic complete response...
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Predicting breast cancer drug response using a multiple-layer cell line drug. Therefore, this study aimed to develop a drug response prediction model for BC using multiple data types from both cell lines and drugs.. Methods: We first collected the baseline gene expression profiles of 49 BC cell lines along with IC 50 values for 220 drugs tested in these cell...
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strategy for EGFR/HER2 targeted therapy resistant breast cancer. Methods: To determine novel mechanisms of EGFR/HER2 therapy resistance in breast cancer, gefitinib or lapatinib resistant variants were created from SKBR3 breast cancer cells. Conclusions: Rac inhibition may represent a viable strategy for treatment of EGFR/HER2 targeted therapy resistant breast cancer.. Effect of EGFR therapy on apoptosis in therapy resistant breast cancer...
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Co-occurrence of thyroid and breast cancer is associated with an increased oncogenic SNP burden. Methods: In this retrospective case-control study we compared the genetic profile of patients with a history of breast cancer (n = 15) to patients with co-occurring breast and thyroid cancer (n = 19) using next generation sequencing of 112 hereditary cancer risk genes. Identified variants were...
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Identification of women at risk for. hereditary breast and ovarian cancer in a sample of 1000 Slovenian women: a. Background: An important number of breast and ovarian cancer cases is due to a strong genetic predisposition.. The number of women identified, the characteristics of the high-risk population, and the agreement between the guidelines were explored.. Results: NCCN guidelines identify 13.2%...
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Associations between multimorbidity and depression among breast cancer survivors within the UK Biobank cohort: a cross-. Background: Advances in the early detection of cancer and its treatment have resulted in an increasing number of people living with and beyond breast cancer. Multimorbidity is also becoming more common in this population as more people live longer with breast cancer and experience...
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The role of postmastectomy radiation in patients with ypN0 breast cancer after neoadjuvant chemotherapy: a meta- analysis. Background: It has been demonstrated that postmastectomy radiation therapy (PMRT) was beneficial for breast cancer patients who are axillary lymph node-positive. 95% CI P = 0.007), particularly in patients with stage III breast cancer (RR, 0.16. The images or other third party material...