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Chủ đề : Cervical cancer


Có 20+ tài liệu thuộc chủ đề "Cervical cancer"

The quality of life in women with cervical cancer and precancerous lesions of Han and ethnic minorities in Southwest China

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The quality of life in women with cervical cancer and precancerous lesions of Han and ethnic minorities in Southwest China. Background: As patients with cervical cancer and precancerous lesions can be diagnosed at early stage and live longer, it is imperative to understand their health-related quality of life so that better cancer-related policies could be promoted and reasonable distribution of...

Survival impact of additional chemotherapy after adjuvant concurrent chemoradiation in patients with early cervical cancer who underwent radical hysterectomy

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Survival impact of additional chemotherapy after adjuvant concurrent chemoradiation in patients with early cervical cancer who underwent radical hysterectomy. The study ( n = 61) and control groups ( n = 137) had similar patient age, histologic cancer type, 2009 FIGO stage, and tumor size. However, minimally invasive surgery was performed less frequently in the study group than in the...

Lymphatic leakage after pelvic lymphadenectomy for cervical cancer: A retrospective case-control study

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Lymphatic leakage after pelvic. lymphadenectomy for cervical cancer:. Background: The study aims to evaluate the clinical features and management of postoperative lymphatic leakage (PLL) in patients with cervical cancer who received pelvic lymphadenectomy.. Methods: This retrospective study screened consecutive patients with cervical cancer (stage Ia2-IIb).. P = 0.013), a decrease in hemoglobin level of ≥ 20 and <. Keywords: Lymphatic...

Bioinformatics analysis of the transcriptional expression of minichromosome maintenance proteins as potential indicators of survival in patients with cervical cancer

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Bioinformatics analysis of the transcriptional expression of. Methods: To explore the role of MCMs and their related genes in cervical cancer, various bioinformatics methods were performed. First, the ONCOMINE and UALCAN databases were used to analyze the mRNA expression of different MCMs. The Human Protein Atlas database was used to analyze the protein expression of MCMs in normal and tumor...

Effectiveness comparisons of various therapies for FIGO stage IB2/IIA2 cervical cancer: A Bayesian network meta-analysis

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therapies for FIGO stage IB2/IIA2 cervical cancer: a Bayesian network meta-analysis. Background: Cervical cancer is a common malignancy of the female genital tract. Treatment options for cervical cancer patients diagnosed at FIGO (2009) stage IB2 and IIA2 remains controversial.. Thirteen randomized controlled trials of FIGO (2009) IB2 and IIA2 cervical cancer patients were included in the final analysis. Conclusion: These...

HPV-specific risk assessment of cervical cytological abnormalities

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HPV-specific risk assessment of cervical cytological abnormalities. Background: Cytology and HPV genotype screening play an important role in cervical cancer detection. Methods: Two thousand two hundred twenty-four females were analyzed for cytology and HPV genotypes test.. A total of 688 patients were detected with HPV infection, 619 with HR-HPV infection and 112 with LR-HRV infection. HPV-52 was found to be...

Association study of relationships of polymorphisms in the miR-21, miR-26b, miR-221/222 and miR-126 genes with cervical intraepithelial neoplasia and cervical cancer

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Association study of relationships of polymorphisms in the miR-21 , miR-26b, miR-221/222 and miR-126 genes with cervical intraepithelial neoplasia and cervical cancer. Methods: Ten single-nucleotide polymorphisms (SNPs) in the miR-21 , miR-26b , miR-221/222 and miR-126 genes (rs1292037, rs13137 in miR-21 . rs2227255, rs2227258 in miR-26b . rs2858061, rs34678647, rs2858060, rs2745709 in miR- 221/222 . rs2297537, rs2297538 in miR-126 )...

Cervical cancer screening “see and treat approach”: Real-life uptake after invitation and associated factors at health facilities in Gondar, Northwest Ethiopia

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Cervical cancer screening “ see and treat approach. Background: Although cervical cancer is a preventable disease, screening coverage in Ethiopia is far below the target. Thus, this study was conducted to assess uptake and associated factors with the cervical cancer screening “ see and treat approach ” among eligible women in public health facilities in Gondar town, Northwest Ethiopia.. Participants...

The importance of choosing the right strategy to treat small cell carcinoma of the cervix: A comparative analysis of treatments

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strategy to treat small cell carcinoma of the cervix: a comparative analysis of treatments. Background: Standard treatments for small cell carcinoma of the cervix (SCCC) have not been established. The median age of the included patients was 47 (range: 24 – 83) years. Of 53 patients who had undergone chemotherapy, 35 and 18 received SCCC and non-SCCC regimens as their...

Comparison of survival outcomes with or without Para-aortic lymphadenectomy in surgical patients with stage IB1-IIA2 cervical cancer in China from 2004 to 2016

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Comparison of survival outcomes with or without Para-aortic lymphadenectomy in surgical patients with stage IB1-IIA2 cervical cancer in China from 2004 to 2016. Background: Current opinions on whether surgical patients with cervical cancer should undergo para-aortic lymphadenectomy at the same time are inconsistent. The present study examined differences in survival outcomes with or without para-aortic lymphadenectomy in surgical patients with...

Contemporary treatment patterns and survival of cervical cancer patients in Ethiopia

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Contemporary treatment patterns and survival of cervical cancer patients in Ethiopia. Background: Cervical cancer is the second commonly diagnosed cancer and the second leading cause of cancer death in women in Ethiopia, with rates among the highest worldwide. However, there are limited data on cervical cancer treatment patterns and survival in the country. Herein, we examine treatment patterns and survival...

SNX10 and PTGDS are associated with the progression and prognosis of cervical squamous cell carcinoma

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To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.. RRA package was download (http://cran.r-project.org/) [9]. Search Tool for the Retrieval of Interacting Genes Data- base (STRING) [11] (http://www.string-db.org/) was used to assess PPI...

A clinical study of pegylated recombinant human granulocyte colony stimulating factor (PEG-rhG-CSF) in preventing neutropenia during concurrent chemoradiotherapy of cervical cancer

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Methods: From August 2018 to April 2020, 60 patients who were pathologically confirmed as cervical cancer were randomly divided into two groups at a ratio of 2:1: PEG-modified-rhG-CSF experimental group and control group.. The primary endpoints were the incidence of grade 3 – 4 neutropenia. Secondary endpoints included the duration of grade 3 – 4 neutropenia, the incidence of grade...

Assessing service availability and readiness to manage cervical cancer in Bangladesh

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Assessing service availability and readiness to manage cervical cancer in Bangladesh. Background: The second most common cancer among females in Bangladesh is cervical cancer. The national strategy for cervical cancer needs monitoring to ensure that patients have access to care. In order to provide accurate information to policymakers in Bangladesh and other low and middle income countries, it is vital...

SOX14 hypermethylation as a tumour biomarker in cervical cancer

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SOX14 hypermethylation as a tumour biomarker in cervical cancer. The aim of this study was to identify and validate the potential value of SOX14 methylation in the early detection of cervical cancer.. Methods: First, we extracted the data for SOX14 methylation and expression within cervical cancer from The Cancer Genome Atlas (TCGA) database and analysed them via UALCAN, Wanderer, MEXPRESS...

Bioinformatics analysis of differentially expressed genes and pathways in the development of cervical cancer

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Bioinformatics analysis of differentially expressed genes and pathways in the development of cervical cancer. Background: This study aimed to explore and identify key genes and signaling pathways that contribute to the progression of cervical cancer to improve prognosis.. DEGs were enriched in 22 biological processes, 16 cellular components and 9 molecular functions in precancerous lesions and cervical cancer. Conclusions: These...

Ultrasound-guided fine needle aspiration cytology of Para-aortic lymph node metastasis in uterine cervical cancer: Diagnostic accuracy and impact on clinical decision making

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Ultrasound-guided fine needle aspiration cytology of Para-aortic lymph node. metastasis in uterine cervical cancer:. Cytological results obtained with US-FNAC were classified by the same experienced cellular pathologists. The effect of US-FNAC on clinical decision making was evaluated.. Results: Cytological results of US-FNAC were categorized as malignancy ( n = 62. All patients tolerated the US-FNAC procedure well and only nine...

Development and validation of a clinical prediction model for endocervical curettage decision-making in cervical lesions

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Background: In the absence of practical and reliable predictors for whether the endocervical curettage (ECC) procedure should be performed, decisions regarding patient selection are usually based on the colposcopists ’ clinical judgment instead of evidence. The ECC. The ECC prediction model was developed based on the following predictors: age, menopause, symptom of contact bleeding, severity of TCT, HPV status, cervix...

Oncogenic role of ALX3 in cervical cancer cells through KDM2B-mediated histone demethylation of CDC25A

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Oncogenic role of ALX3 in cervical cancer cells through KDM2B-mediated histone demethylation of CDC25A. This work focused on the function of CDC25A in cervical cancer cell growth and the molecules involved.. The CDC25A expression in cancer and normal tissues was predicted in the GEPIA database and that in CSCC and normal cells was determined by RT-qPCR and western blot assays....

Feasibility and first results of a prospective cohort study to investigate cisplatinassociated ototoxicity amongst cancer patients in South Africa

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Background: Cervical cancer, one of the most common cancers affecting females in South Africa, commonly requires a cisplatin-based-treatment regimen, which has been associated with ototoxic side effects. However, cisplatin-associated ototoxicity is largely under-reported in South Africa, despite its impact of hearing loss having serious overt ramifications on the quality of life of these patients. Objective: To present details of the...