Có 13+ tài liệu thuộc chủ đề "Cell cycle"
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Results: In the present study, analyses of physiological responses and transcriptional events between IL10 – 1 (resistant line) and CC3 (susceptible line) were conducted after M. incognita in IL10 – 1, which were the primary differences compared with CC3. Furthermore, Gene ontology (GO) analysis revealed that genes encoding cell wall proteins were up-regulated in IL10 – 1 and that the...
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accelerate cell cycle progression in advanced hepatocellular carcinoma. Two lncRNAs, the highly expressed lncRNA in recurrent HCC (HERH)-1 and HERH-4, were upregulated in the advanced HCC cells. HERH-1/4 enhanced proliferation and promoted DNA replication and G1-S transition during the cell cycle in HCC cells. Conclusions: The oncogenic lncRNA HERH-1/4 promoted CCNA2 expression at the transcriptional and post- transcriptional levels and...
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Infiltration of CD1a-positive dendritic cells in advanced laryngeal cancer correlates with unfavorable outcomes post-. Background: The prognosis of advanced laryngeal cancer is unfavorable despite advances in multidisciplinary therapy. Tumor-infiltrating CD1a + DCs have been reported to be associated with clinical outcomes in carcinomas of various organs, but the clinical impact of CD1a + DCs in laryngeal cancer remains to be...
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Genetic predisposition to male breast cancer in Poland. Background: Breast cancer in men accounts for fewer than 1 % of all breast cancer cases diagnosed in men and women. Genes which predispose to male breast cancer include BRCA1 and BRCA2. Methods: We estimated the prevalence of 20 alleles in six genes ( BRCA1 , BRCA2 , CHEK2 , PALB2 ,...
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Background: Minichromosome maintenance complex component 6 (MCM6), as an important replication permission factor, is involved in the pathogenesis of various tumors. Here we studied the expression of MCM6 in neuroblastoma and its influence on tumor characteristics and prognosis.. Methods: Publicly available datasets were used to explore the influence of the differential expression of MCM6 on neuroblastoma tumor stage, risk and...
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Molecular and cellular characterization of two patient-derived ductal carcinoma in situ (DCIS) cell lines, ETCC-006 and ETCC- 010. Here we have conducted a detailed molecular and cellular characterization of two, patient-derived, ductal carcinoma in situ (DCIS) cell lines, ETCC-006 and ETCC-010.. Methods: Human DCIS cell lines, ETCC-006 and ETCC-010, were compared against a panel of cell lines including the immortalized,...
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Oncogenic role of ALX3 in cervical cancer cells through KDM2B-mediated histone demethylation of CDC25A. This work focused on the function of CDC25A in cervical cancer cell growth and the molecules involved.. The CDC25A expression in cancer and normal tissues was predicted in the GEPIA database and that in CSCC and normal cells was determined by RT-qPCR and western blot assays....
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Regulation of E2F1 activity via PKA-mediated phosphorylations. E2F family members play an important role in the regulation of the cell cycle and apoptosis. Hazar-Rethinam et al., 2011). Kaelin et al., 1992). The expression of activator E2F members is regulated by the cell cycle, and their level reaches to a maximum at the G1/S phase of the cell cycle (DeGregori et...
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doi:10.3906/biy-2002-30. Many factors, including inflammatory bowel disease, colon involvement, epigenetic changes, and family history, are closely related to the progression of CRC (Johnson et al., 2013). Increased age and a lifestyle including high meat consumption, low vegetable consumption, low physical activity, and high alcohol and food consumption are major factors that influence CRC development (Cunningham et al., 2010).. of signaling...
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Effects of bradykinin on proliferation, apoptosis, and cycle of glomerular mesangial cells via the TGF-β1/Smad signaling pathway. Glomerular mesangial cells are primary effector cells for the progression of chronic progressive kidney diseases into renal fibrosis (Lee et al., 2018). Mesangial cells are activated by multiple factors-triggered inflammatory cytokines to cause hyperproliferation, which enlarges the kidney mesangial area and decreases the...
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doi:10.3906/biy-2009-6. Arid4b alters cell cycle and cell death dynamics during mouse embryonic stem cell differentiation. Embryonic stem cells (ESC) are pluripotent and self- renewing cells that originate from the inner cell mass (ICM) of the developing blastocyst. The ESC state is transcriptionally maintained by pluripotency transcription factors (TFs) and chromatin factors (Masui et al., 2007). Sin3a is a multisubunit corepressor...
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apoptosis and cell cycle of peripheral blood lymphocytes, and immunologic function. The effects of WAGs on peripheral blood lymphocytes, however, remain yet controversial. The present study was undertaken to examine the effects of occupational sevoflurane exposure on the peripheral blood lymphocytes of medical personnel who work in the operating room.. Methods: A cohort of 56 medical residents were divided into...
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prediction in patients with clear cell renal cell carcinoma. Background: It is of great urgency to explore useful prognostic markers for patients with clear cell renal cell carci- noma (ccRCC). Prognostic models based on ferroptosis-related gene (FRG) in ccRCC is poorly reported for now.. We carried out least absolute shrinkage and selection operator analysis to screen out prognosis-related FRGs and...