Có 20+ tài liệu thuộc chủ đề "Intensive care unit"
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with idiopathic pulmonary fibrosis treated with antifibrotic medications. Background: Idiopathic Pulmonary Fibrosis is a chronic, progressive interstitial lung disease for which there is no cure. Historical outcomes for hospitalized patients with Idiopathic Pulmonary Fibrosis are grim. insurance database, we created a one-to-one propensity score matched cohort of patients with idiopathic pulmonary fibrosis treated and untreated with an antifibrotic who underwent...
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Cyclophosphamide for interstitial lung. disease-associated acute respiratory failure:. Background: Treatment for interstitial lung disease (ILD) patients with acute respiratory failure (ARF) is challenging, and literature to guide such treatment is scarce. The reported in-hospital mortality rates of ILD patients with ARF are high (62–66. Cyclophosphamide is considered a second-line treatment in steroid-refractory ILD-associated ARF.. The first aim of this study...
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variation rate is associated with mortality among critically ill patients with acute. This study aims to explore the relationship between dynamic changes in MP and prognosis in critically ill patients.. 10 J/min on admission in the ICU were included. [(peak inspiratory pressure + positive end-expiratory pressure)/2] and the MP variation rate. as ([baseline MP − 24-h MP]/baseline MP. Patients were...
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Validation of APACHE II, APACHE III and SAPS II scores in in-hospital and one year mortality prediction in a mixed intensive care unit in Poland: a cohort study. Background: There are several scores used for in-hospital mortality prediction in critical illness. We aimed to validate APACHE II, APACHE III and SAPS II scores in short- and long-term mortality prediction in...
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Background: It is not clear whether there are valuable inflammatory markers for prognosis judgment in the intensive care unit (ICU). The AUC-ROC values of PCT and CRP for discriminating ICU mortality were confidence interval [CI and CI respectively. In the multivariable analysis, only APACHE II score (odds ratio, 1.166. P = 0.001), were significantly associated with an increased risk of...
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Persistently higher serum sCD40L levels are associated with outcome in septic patients. Methods: Time changes in sCD40L levels were assessed for 3 days after ICU admission in 49 patients with SS and compared with those in 19 SWS patients. Serum sCD40L concentration was detected by ELISA. Results: SS had significantly higher sCD40L levels than SWS and control patients. We observed...
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Development and validation of a predictive score for ICU delirium in critically ill. Background: The incidence of delirium in intensive care unit (ICU) patients is high and associated with a poor prognosis. We validated the risk factors of delirium to identify relevant early and predictive clinical indicators and developed an optimized model.. Methods: In the derivation cohort, 223 patients were...
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Effectiveness of securing central venous catheters with topical tissue adhesive in patients undergoing cardiac surgery: a randomized controlled pilot study. Topical tissue. adhesives form a thin film of coating that becomes bound to keratin in the epidermis. This study aimed to evaluate fixation of CVCs with topical tissue adhesive in patients (prone to bleed) undergoing cardiac surgery regarding its ability...
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Parallel veno-venous and veno-arterial extracorporeal membrane circuits for coexisting refractory hypoxemia and cardiovascular failure: a case report. Background: The complexity of extracorporeal membrane oxygenation (ECMO) techniques continues to evolve.. cardiovascular and pulmonary physiology of the patients. Case presentation: We present the case of a 25-year-old morbidly obese male patient admitted for severe acute respiratory distress syndrome (ARDS) and refractory hypoxemia,...
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However, caffeine withdrawal and the therapeutic use of caffeine in intensive care and in the perioperative period have not been well summarised. Our objective was to conduct a scoping review of caffeine withdrawal and use in the intensive care unit (ICU) and postoperative patients.. Methods: PubMed, Embase, CINAHL Complete, Scopus and Web of Science were systematically searched for studies investigating...
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Risk factors for unplanned reintubation caused by acute airway compromise after general anesthesia: a case-control study. Background: This study aimed to identify the risk factors and evaluate the prognosis of unplanned reintubation caused by acute airway compromise (AAC) after general anesthesia.. Methods: This case-control study included surgical patients who underwent unplanned reintubation in the operating room and postanesthesia care unit...
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Association between the modified Nutrition Risk in Critically Ill (mNUTRIC) score and clinical outcomes in the intensive care unit: a secondary analysis of a large prospective observational. The modified nutrition risk in the critically ill score (mNUTRIC) was proposed as an appropriate nutritional assessment tool in critically ill patients, but it has not been fully demonstrated and widely used. Our...
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Outcome after intubation for septic shock with respiratory distress and hemodynamic compromise: an observational study. The purpose of this study was to evaluate the impact of intubation in patients with respiratory distress and predominant hemodynamic instability within 24 h after ICU admission for septic shock.. Methods: We conducted a retrospective analysis of a prospective registry of adult patients with septic...
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Association between enterocyte injury. and fluid balance in patients with septic shock:. Background: The required fluid volume differs among patients with septic shock. This study aimed to evaluate the association between enterocyte injury and positive fluid balance in patients with septic shock.. Methods: This study was a post hoc exploratory analysis of a prospective observational study that assessed the association...
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Acute kidney injury risk prediction score for critically-ill surgical patients. Background: There has been a global increase in the incidence of acute kidney injury (AKI), including among critically-ill surgical patients. AKI prediction score provides an opportunity for early detection of patients who are at risk of AKI. however, most of the AKI prediction scores were derived from cardiothoracic surgery. Therefore,...
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Effect of sedation with dexmedetomidine or propofol on gastrointestinal motility in lipopolysaccharide-induced endotoxemic mice. Methods: Sedative/Anesthetic Scores and vital signs of lipopolysaccharide (LPS)-induced endotoxemic mice were measured during sedation with propofol or dexmedetomidine. Endotoxemic mice were divided into 10% fat emulsion, propofol, saline, and dexmedetomidine group. Results: 40 mg·kg − 1 propofol and 80 μ g·kg − 1 dexmedetomidine induced...
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Emergency tracheal intubation during off- hours is not associated with increased. Our aim was to evaluate the 30-d hospitalization mortality of subjects undergoing ETI during daytime or off-hours and to analyze the possible risk factors affecting mortality.. All adult inpatients who received ETI in the general ward were included. department in which ETI was performed (surgical ward or medical ward),...
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Background: To compare patients hospitalised in the intensive care unit (ICU) after surgery for community- acquired intra-abdominal infection (CA-IAI) and hospital-acquired intra-abdominal infection (HA-IAI) in terms of mortality, severity and complications.. Patients with CA-IAI had an increased 28-day mortality rate compared to those with HA-IAI (30% vs 15%, respectively (p = 0.009. At 90 days, the mortality rates were 36.7...
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Continuous EEG monitoring by a new. simplified wireless headset in intensive care unit. Background: In critically ill patients continuous EEG (cEEG) is recommended in several conditions. In Study group, cEEG was recorded by CerebAir®. assembled by an ICU physician, while in Control group a simplified 8-electrodes-EEG recording positioned by an EEG technician was performed.. Results: Time for electrodes applying was...
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Predictors of 1-year mortality in patients on prolonged mechanical ventilation after. Objectives: The requirement of prolonged mechanical ventilation (PMV) is associated with increased medical care demand and expenses, high early and long-term mortality, and worse life quality. However, no study has assessed the prognostic factors associated with 1-year mortality among PMV patients, not less than 21 days after surgery. This...