Có 20+ tài liệu thuộc chủ đề "Gastric cancer"
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Methods: We retrospectively analyzed 1515 MPA patients in SEER database. Results: No significant differences were noted in OS and CSS time. The MPA patients who were treated with surgery and chemotherapy exhibited longer OS and CSS time periods than those without treatment. MPA patients treated with radiotherapy exhibited similar OS and CSS time with those without radiotherapy. Conclusions: MPA was...
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adenocarcinoma – the phase III “ PREVENT. (FLOT9) trial of the AIO /CAOGI /ACO. with localized and locally advanced diffuse or mixed type (Laurens ’ s classification) adenocarcinoma of the stomach and Type II/III GEJ.. Full list of author information is available at the end of the article. with gastric cancer and no peritoneal involvement will not be treated with...
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classification of gastric cancer location for function preserving gastrectomy based on physiological lymphatic flow. Background: The correlation between tumor location and lymphatic flow distribution in gastric cancer has been previously reported, and PTD (Proximal – Transitional – Distal) classification was proposed. In this study, the distribution of dyed lymphatic flow was evaluated for each occupied area of the tumor.. The...
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The long-term survival outcomes of gastric cancer patients with total intravenous. Background: The relationship between the type of anesthesia and the survival outcomes of gastric cancer patients is uncertain. This study compared the overall outcome of gastric cancer patients after surgery with total intravenous anesthesia (TIVA) or inhalation anesthesia (IHA).. Methods: Clinicopathological variables of gastric cancer patients were retrieved from...
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Impact of skeletal muscle mass in patients with unresectable gastric cancer who. Background: The mortality rate of patients with unresectable gastric cancer (UGC) has decreased with the development of chemotherapies and surgical techniques. retrospectively examined the prognostic significance of the pretreatment skeletal muscle mass index (SMI) and nutritional and inflammatory factors in patients with UGC.. The incidence of grade 3...
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A novel ferroptosis-related lncRNA. This study aimed to screen the prognostic ferroptosis-related lncRNAs and to construct a prognostic risk model for GC.. Methods: Ferroptosis-related lncRNAs from The Cancer Genome Atlas (TCGA) GC expression data was downloaded.. First, single factor Cox proportional hazard regression analysis was used to select seven prognostic ferroptosis- related lncRNAs from TCGA database. Results: We constructed a...
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Preferences of first-degree relatives of gastric cancer patients for gastric cancer screening: a discrete choice experiment. Background: It is very necessary to implement gastric cancer screening in China to reduce the mortality of gastric cancer, but there are no national screening guidelines and programs. In addition, the first-degree relatives of gastric cancer patients are at high risk for gastric cancer....
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Adjuvant chemotherapy is an additional option for locally advanced gastric cancer after radical gastrectomy with D2. Background: This study compared the long-term efficacy of different durations of adjuvant chemotherapy for patients with gastric cancer after radical gastrectomy with D2 lymphadenectomy.. Methods: We retrospectively identified 428 patients with stage II – III gastric cancer who underwent D2 gastrectomy between 2009 and...
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Postoperative morbidity and quality of life between totally laparoscopic total. gastrectomy and laparoscopy-assisted total gastrectomy: a propensity-score matched analysis. Background: This study aimed to evaluate the surgical outcome and quality of life (QoL) of totally laparoscopic total gastrectomy (TLTG) compared with laparoscopy-assisted total gastrectomy (LATG) in patients with clinical stage I gastric cancer.. To view a copy of this licence,...
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To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.. Previous studies have demonstrated that single nucleo- tide polymorphisms (SNPs) are associated with chemotherapy-associated toxicity [10–12]. 10.31). 10.08). Nugent et al. Utilizing a classification...
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The prognostic impact of macroscopic serosal change on resectable advanced gastric cancer. Background: Advanced gastric cancer sometimes causes macroscopic serosal change (MSC) due to direct invasion or inflammation. Methods: A total of 1410 patients who had been diagnosed with deeper-than-pathological-T2 gastric cancer and undergone R0 gastrectomy with lymph node dissection at the National Cancer Center Hospital during January 2000 and...
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Results of the observational prospective RealFLOT study. Aim of the study was to describe feasibility and safety of FLOT, pathological complete response rate (pCR), surgical outcomes and overall response rate (ORR) in an. Neutropenia was the most common G 3 – 4 adverse event (AE): 19.9% in the preoperative phase and 16.9% in the postoperative phase. ORR was 45.6% and...
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chemotherapy with docetaxel/cisplatin/S-1 followed by S-1 for stage III gastric cancer. chemotherapy with docetaxel/cisplatin/S-1 (DCS) following S-1 therapy in patients with stage III gastric cancer after curative gastrectomy.. Methods: Patients with stage III gastric cancer who underwent D2 gastrectomy were enrolled. Adjuvant chemotherapy was initiated within 8 weeks of gastrectomy. Conclusion: The DCS regimen can be acceptable as an adjuvant...
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The predictive efficacy of the signature for chemotherapy and immunotherapy was also tested. We found that the low-risk group presented with better survival (Kaplan-Meier analysis, p <. As for the practicality of this signature, the IC50 of cytotoxic chemotherapeutics was significantly higher in the high-risk group. The low-risk group also presented with higher immunophenoscore (IPS) in both the “ CTLA4+...
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LncRNA LINC00342 promotes gastric cancer progression by targeting the miR-545-5p/. Methods: The expression of LINC00342 in GC tissues was evaluated by Quantitative reverse transcription. Silencing of LINC00342 was conducted to investigate the effect of LINC00342 in vitro and in vivo. In addition, a tumor model was used to verify the effect of LINC00342 in tumorigenesis in vivo.. Silencing of LINC00342...
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Results: We found that loss of function of CSK or PTEN conferred lapatinib resistance in HER2-amplified GC cell lines NCI-N87 and OE19, respectively. Moreover, PI3K and MAPK signaling was significantly increased in CSK or PTEN null cells. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. [email protected]. We also demonstrated that the lapatinib resistance involves restoration of the PI3K/AKT and...
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Efficacy of systemic oncological treatments in patients with advanced esophageal or gastric cancers at high risk of dying in the middle and short term: an overview of. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line...
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Identification of novel hub genes associated with gastric cancer using integrated bioinformatics analysis. Background: Gastric cancer (GC) is one of the most common solid malignant tumors worldwide with a high- recurrence-rate. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated...
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prognosis and efficacy of chemotherapy in gastric cancer. Background: Gastric cancer (GC) is a primary reason for cancer death in the world. Gastric cancer (GC) ranks the 6th place in terms of can- cer morbidity, and it is also the 5th cause of cancer deaths in the world [1]. Therefore, the evaluation of the overall survival, progression-free inter- val (PFI)...